Induction of CPP32-like activity in PC12 cells by withdrawal of trophic support. Dissociation from apoptosis

scientific article published on 01 November 1996

Induction of CPP32-like activity in PC12 cells by withdrawal of trophic support. Dissociation from apoptosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.271.48.30663
P698PubMed publication ID8940042

P50authorDavid S ParkQ60560240
P2093author name stringL A Greene
L Stefanis
M L Shelanski
C Y Yan
S E Farinelli
C M Troy
P2860cites workEstablishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factorQ24561804
P433issue48
P407language of work or nameEnglishQ1860
P921main subjectapoptotic processQ14599311
P304page(s)30663-30671
P577publication date1996-11-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleInduction of CPP32-like activity in PC12 cells by withdrawal of trophic support. Dissociation from apoptosis
P478volume271

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cites work (P2860)
Q52190233A developmental timer that regulates apoptosis at the onset of gastrulation.
Q40938391A dual topoisomerase inhibitor, TAS-103, induces apoptosis in human cancer cells
Q77772404A predominant apoptotic death pathway of neuronal PC12 cells induced by activated microglia is displaced by a non-apoptotic death pathway following blockage of caspase-3-dependent cascade
Q53653335Ataxia telangiectasia-mutated protein can regulate p53 and neuronal death independent of Chk2 in response to DNA damage.
Q36273925Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death.
Q28588398Bax-dependent caspase-3 activation is a key determinant in p53-induced apoptosis in neurons
Q40884748Bcl-xS and Bax induce different apoptotic pathways in PC12 cells
Q37184754Calcium overload is essential for the acceleration of staurosporine-induced cell death following neuronal differentiation in PC12 cells
Q44422893Calpains mediate p53 activation and neuronal death evoked by DNA damage.
Q36342515Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarization
Q77508889Caspase-2 (Nedd-2) processing and death of trophic factor-deprived PC12 cells and sympathetic neurons occur independently of caspase-3 (CPP32)-like activity
Q73419649Caspase-2 mediates neuronal cell death induced by beta-amyloid
Q83002265Caspase-3 activity in hippocampal slices reflects changes in synaptic plasticity
Q40492646Caspase-9 plays a marginal role in serum starvation-induced apoptosis
Q48157353Caspase-dependent and -independent death of camptothecin-treated embryonic cortical neurons
Q33581801Caspases and nitric oxide broadly regulate dendritic cell maturation and surface expression of class II MHC proteins
Q73212113Conformational and molecular basis for induction of apoptosis by a p53 C-terminal peptide in human cancer cells
Q54020659CrmA protects against apoptosis and ceramide formation in PC12 cells.
Q73863849Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons
Q45054555Deacetylation of p53 after nerve growth factor treatment in PC12 cells as a post-translational modification mechanism of neurotrophin-induced tumor suppressor activation
Q28141648Delayed mitochondrial dysfunction in excitotoxic neuron death: cytochrome c release and a secondary increase in superoxide production
Q73315751Delaying caspase activation by Bcl-2: A clue to disease retardation in a transgenic mouse model of amyotrophic lateral sclerosis
Q52533916Differential expression and translocation of protein tyrosine phosphatase 1B-related proteins in ME-180 tumor cells expressing apoptotic sensitivity and resistance to tumor necrosis factor: potential interaction with epidermal growth factor receptor
Q28576044Differential roles of nuclear and cytoplasmic cyclin-dependent kinase 5 in apoptotic and excitotoxic neuronal death
Q52542101Distinction between differentiation, cell cycle, and apoptosis signals in PC12 cells by the nerve growth factor mutant delta9/13, which is selective for the p75 neurotrophin receptor.
Q39765027Effects of ADMA on gene expression and metabolism in serum-starved LoVo cells
Q73295616Enhanced caspase activity during ethanol-induced apoptosis in rat cerebellar granule cells
Q43819951Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death.
Q38525125Hwansodan protects PC12 cells against serum-deprivation-induced apoptosis via a mechanism involving Ras and mitogen-activated protein (MAP) kinase pathway
Q33178723Immunolocalization of caspase proteolysis in situ: evidence for widespread caspase-mediated apoptosis of neurons and glia in the postnatal rat brain
Q35059087Induction of apoptosis in cancer cell lines by the Red Sea brine pool bacterial extracts
Q73755030Inhibition of caspase-3 activation by SB 203580, p38 mitogen-activated protein kinase inhibitor in nitric oxide-induced apoptosis of PC-12 cells
Q43814130Inhibitors of trypsin-like serine proteases prevent DNA damage-induced neuronal death by acting upstream of the mitochondrial checkpoint and of p53 induction.
Q44045947Interaction of the c-Jun/JNK pathway and cyclin-dependent kinases in death of embryonic cortical neurons evoked by DNA damage
Q34510381Intracellular, nonreceptor-mediated signaling by adenosine: induction and prevention of neuronal apoptosis
Q44611104Lithium inhibits apoptosis of mouse neural progenitor cells
Q73104356M1 muscarinic receptors block caspase activation by phosphoinositide 3-kinase- and MAPK/ERK-independent pathways
Q74070484Multiple pathways of neuronal death induced by DNA-damaging agents, NGF deprivation, and oxidative stress
Q73101267Nedd2 is required for apoptosis after trophic factor withdrawal, but not superoxide dismutase (SOD1) downregulation, in sympathetic neurons and PC12 cells
Q44659617Need for caspases in apoptosis of trophic factor-deprived PC12 cells
Q40596476Nerve growth factor withdrawal-mediated apoptosis in naive and differentiated PC12 cells through p53/caspase-3-dependent and -independent pathways
Q37441614NeuroD6 genomic signature bridging neuronal differentiation to survival via the molecular chaperone network
Q77343222Neuronal death and survival in two models of hypoxic-ischemic brain damage
Q48739119Neurons in Alzheimer disease emerge from senescence
Q42851045New isolation technique to study apoptosis in human intestinal epithelial cells
Q78094837Nitric oxide protects PC12 cells from serum deprivation-induced apoptosis by cGMP-dependent inhibition of caspase signaling
Q37828672Ordering the multiple pathways of apoptosis
Q36158347Passage Variation of PC12 Cells Results in Inconsistent Susceptibility to Externally Induced Apoptosis
Q77354539Periods of postnatal maturation of hippocampus: synaptic modifications and neuronal disconnection
Q40576035Prion protein fragment 106-126 induces a p38 MAP kinase-dependent apoptosis in SH-SY5Y neuroblastoma cells independently from the amyloid fibril formation.
Q34275921Proteinase families and their inhibitors
Q75426843RAIDD aggregation facilitates apoptotic death of PC12 cells and sympathetic neurons
Q33181921Ribozyme-mediated inhibition of caspase-3 activity reduces apoptosis induced by 6-hydroxydopamine in PC12 cells
Q48094020Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis.
Q59393051Selective inhibitors of apoptotic caspases: implications for novel therapeutic strategies
Q39476761Staurosporine-induced apoptosis of cultured rat hippocampal neurons involves caspase-1-like proteases as upstream initiators and increased production of superoxide as a main downstream effector.
Q38522793Sunghyangjungisan protects PC12 cells against neurotoxicity elicited by withdrawal of trophic support via CRE activation
Q43760336Tau and HMW tau phosphorylation and compartmentalization in apoptotic neuronal PC12 cells
Q34474341The basic helix-loop-helix transcription factor Nex-1/Math-2 promotes neuronal survival of PC12 cells by modulating the dynamic expression of anti-apoptotic and cell cycle regulators.
Q39682246The herpes simplex virus type 2 R1 protein kinase (ICP10 PK) blocks apoptosis in hippocampal neurons, involving activation of the MEK/MAPK survival pathway
Q33870484The neurogenic basic helix-loop-helix transcription factor NeuroD6 confers tolerance to oxidative stress by triggering an antioxidant response and sustaining the mitochondrial biomass.
Q48417812The role of caspase-3 activation in phencyclidine-induced neuronal death in postnatal rats
Q77125943Thrombin perturbs neurite outgrowth and induces apoptotic cell death in enriched chick spinal motoneuron cultures through caspase activation
Q41823292Veratridine induces apoptotic death in bovine chromaffin cells through superoxide production
Q50644266XLX is an IAP family member regulated by phosphorylation during meiosis.

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