Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys

scientific article published on 01 January 1997

Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/NM0197-73
P2888exact matchhttps://scigraph.springernature.com/pub.10.1038/nm0197-73
P698PubMed publication ID8986744

P50authorJacqueline BresnahanQ67524117
P2093author name stringM S Beattie
M J Crowe
J N Masters
S L Shuman
P2860cites workIdentification of programmed cell death in situ via specific labeling of nuclear DNA fragmentationQ24642901
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Neuronal apoptosis: current understanding of molecular mechanisms and potential role in ischemic brain injuryQ40965347
CNTF protection of oligodendrocytes against natural and tumor necrosis factor-induced death.Q46020332
Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection.Q47331040
Secondary cell death and the inflammatory reaction after dorsal hemisection of the rat spinal cordQ48129257
The effects of methylprednisolone and the ganglioside GM1 on acute spinal cord injury in rats.Q54179139
Differential susceptibility of human CNS-derived cell populations to TNF-dependent and independent immune-mediated injury.Q55480343
A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord InjuryQ56775114
Expression of the APC tumor suppressor protein in oligodendrogliaQ58414677
A neuroanatomical analysis of spinal cord injury in the rhesus monkey (Macaca mulatta)Q67524121
Apoptosis and expression of Bcl-2 after compression trauma to rat spinal cordQ71483698
Cellular inflammatory response after spinal cord injury in Sprague-Dawley and Lewis ratsQ71959419
Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal deathQ72549763
In situ demonstration of mature oligodendrocytes and their processes: an immunocytochemical study with a new monoclonal antibody, ripQ93524085
P433issue1
P921main subjectapoptotic processQ14599311
P304page(s)73-76
P577publication date1997-01-01
P1433published inNature MedicineQ1633234
P1476titleApoptosis and delayed degeneration after spinal cord injury in rats and monkeys
P478volume3

Reverse relations

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Q48172017Myelinogenic Plasticity of Oligodendrocyte Precursor Cells following Spinal Cord Contusion Injury
Q37190678N-Methyl-D-aspartate antagonists and apoptotic cell death triggered by head trauma in developing rat brain
Q48595101Naringin treatment improves functional recovery by increasing BDNF and VEGF expression, inhibiting neuronal apoptosis after spinal cord injury.
Q38212924Natural polyphenols and spinal cord injury
Q36499220Necroptosis, a novel type of programmed cell death, contributes to early neural cells damage after spinal cord injury in adult mice
Q89596868Neonatal hydrocephalus leads to white matter neuroinflammation and injury in the corpus callosum of Ccdc39 hydrocephalic mice
Q60684621Nerve Growth Factor Protects Oligodendrocytes from Tumor Necrosis Factor-α-induced Injury through Akt-mediated Signaling Mechanisms
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Q34172960Neuro-immune interactions of neural stem cell transplants: from animal disease models to human trials
Q79936904Neurocyte apoptosis and expressions of caspase-3 and Fas after spinal cord injury and their implication in rats
Q40207513Neuropathological Characteristics of Brachial Plexus Avulsion Injury With and Without Concomitant Spinal Cord Injury.
Q36045235Neuroprotection and acute spinal cord injury: a reappraisal
Q34975626Neuroprotection and its molecular mechanism following spinal cord injury
Q49269113Neuroprotection by chitosan nanoparticles in oxidative stress-mediated injury.
Q92974052Neuroprotection, Recovery of Function and Endogenous Neurogenesis in Traumatic Spinal Cord Injury Following Transplantation of Activated Adipose Tissue
Q47814324Neuroprotective Activities of Saffron and Crocin
Q37963878Neuroprotective Mechanisms of PPARδ: Modulation of Oxidative Stress and Inflammatory Processes
Q37523905Neuroprotective effects of perflurocarbon (oxycyte) after contusive spinal cord injury
Q47892533Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult rat spinal cord.
Q40526881Neutralization of CD95 ligand promotes regeneration and functional recovery after spinal cord injury.
Q35332802New Prophylactic and Therapeutic Strategies for Spinal Cord Injury
Q78094837Nitric oxide protects PC12 cells from serum deprivation-induced apoptosis by cGMP-dependent inhibition of caspase signaling
Q49105945Nitric oxide via macrophage iNOS induces apoptosis following traumatic spinal cord injury.
Q37074091No evidence for chronic demyelination in spared axons after spinal cord injury in a mouse
Q36540686OLIGODENDROCYTE VULNERABILITY FOLLOWING TRAUMATIC BRAIN INJURY IN RATS: EFFECT OF MODERATE HYPOTHERMIA.
Q34238105Olfactory ensheathing cells - another miracle cure for spinal cord injury?
Q35006477Oligodendrocyte fate after spinal cord injury
Q47233535Oligodendrocyte precursor cell transplantation promotes functional recovery following contusive spinal cord injury in rats and is associated with altered microRNA expression
Q36469769Oligodendrocyte vulnerability following traumatic brain injury in rats
Q59330262Oligodendroglia Are Particularly Vulnerable to Oxidative Damage After Neurotrauma In Vivo
Q57839844Oligodendroglial apoptosis occurs along degenerating axons and is associated with FAS and p75 expression following spinal cord injury in the rat
Q48938399Oligodendroglial cell death with DNA fragmentation in the white matter under chronic cerebral hypoperfusion: comparison between normotensive and spontaneously hypertensive rats.
Q36108225Opposite regulation of oligodendrocyte apoptosis by JNK3 and Pin1 after spinal cord injury
Q39805023Optimal location and time for neural stem cell transplantation into transected rat spinal cord
Q37008474Oral administration of a small molecule targeted to block proNGF binding to p75 promotes myelin sparing and functional recovery after spinal cord injury
Q40465118Overexpression of XIAP inhibits apoptotic cell death in an oligodendroglial cell line.
Q51335031PRDM5 Expression and Essential Role After Acute Spinal Cord Injury in Adult Rat.
Q33748155PTEN inhibitor bisperoxovanadium protects oligodendrocytes and myelin and prevents neuronal atrophy in adult rats following cervical hemicontusive spinal cord injury
Q33915855Passive or active immunization with myelin basic protein promotes recovery from spinal cord contusion.
Q33805235Pathology dynamics predict spinal cord injury therapeutic success
Q73336402Peripheral nerve injury induces endoneurial expression of IFN-gamma, IL-10 and TNF-alpha mRNA
Q34619889Peripheral noxious stimulation reduces withdrawal threshold to mechanical stimuli after spinal cord injury: role of tumor necrosis factor alpha and apoptosis
Q44283543Peroxynitrite generated in the rat spinal cord induces apoptotic cell death and activates caspase-3.
Q52674804Pharmacokinetics and safety of oral glyburide in dogs with acute spinal cord injury.
Q37686358Phospholipase A2 and its molecular mechanism after spinal cord injury
Q83307993Phosphorylated neurofilament subunit NF-H as a biomarker for evaluating the severity of spinal cord injury patients, a pilot study
Q35983143Photothrombosis-induced Focal Ischemia as a Model of Spinal Cord Injury in Mice.
Q50501021Platelet-derived growth factor-responsive neural precursors give rise to myelinating oligodendrocytes after transplantation into the spinal cords of contused rats and dysmyelinated mice.
Q38124780Polyethylene glycol repairs membrane damage and enhances functional recovery: a tissue engineering approach to spinal cord injury
Q35157997Post-traumatic inflammation following spinal cord injury
Q75233280Post-traumatic moderate systemic hypothermia reduces TUNEL positive cells following spinal cord injury in rat
Q24671661Posttraumatic therapeutic vaccination with modified myelin self-antigen prevents complete paralysis while avoiding autoimmune disease
Q37134018Potential Therapeutic Targets for PPARgamma after Spinal Cord Injury
Q55480248Potential Utility of Retinal Imaging for Alzheimer’s Disease: A Review.
Q41716847Potential neuroprotective therapy for glaucomatous optic neuropathy
Q33187322Primary cortical motor neurons undergo apoptosis after axotomizing spinal cord injury
Q28574864ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury
Q36873715Progressive damage after brain and spinal cord injury: pathomechanisms and treatment strategies
Q33944968Proliferation of NG2-positive cells and altered oligodendrocyte numbers in the contused rat spinal cord.
Q48256973Prominent oligodendrocyte genesis along the border of spinal contusion lesions.
Q35092261Prospects for antiapoptotic drug therapy of neurodegenerative diseases
Q44107673Protective effects of oral creatine supplementation on spinal cord injury in rats.
Q33829332Proteomic and phosphoproteomic analyses of the soluble fraction following acute spinal cord contusion in rats
Q48455614Purification of a multipotent antideath activity from bovine liver and its identification as arginase: nitric oxide-independent inhibition of neuronal apoptosis.
Q58766273Quantitative MRI of rostral spinal cord and brain regions is predictive of functional recovery in acute spinal cord injury
Q90119612Quantitative profiling of regional protein expression in rat retina after partial optic nerve transection using fluorescence difference two‑dimensional gel electrophoresis
Q43075178Quercetin attenuates inflammatory processes after spinal cord injury in an animal model
Q28071816Rat models of spinal cord injury: from pathology to potential therapies
Q28248202Reactive astrocytes protect tissue and preserve function after spinal cord injury
Q36542958Reactive astrocytes undergo M1 microglia/macrohpages-induced necroptosis in spinal cord injury
Q38234624Receptor for advanced glycation end products (RAGE) and its ligands: focus on spinal cord injury
Q51215749Regeneration of the rat spinal cord after thoracic segmentectomy: restoration of the anatomical integrity of the spinal cord.
Q36996629Repetitive magnetic stimulation affects the microenvironment of nerve regeneration and evoked potentials after spinal cord injury
Q88532210RhoA activation in axotomy-induced neuronal death
Q35209243RhoA-inhibiting NSAIDs promote axonal myelination after spinal cord injury
Q52581900Role of Caspase-8 and Fas in Cell Death After Spinal Cord Injury.
Q38595955Role of Diffusion Tensor MR Imaging in Degenerative Cervical Spine Disease: a Review of the Literature
Q36864853Rolipram attenuates acute oligodendrocyte death in the adult rat ventrolateral funiculus following contusive cervical spinal cord injury
Q36790871Salvianolic acid B protects the myelin sheath around injured spinal cord axons
Q34471414Secondary degeneration reduced by inosine after spinal cord injury in rats
Q35083357Secretome analysis of human oligodendrocytes derived from neural stem cells
Q24646208Self-assembling nanofibers inhibit glial scar formation and promote axon elongation after spinal cord injury
Q40590302Sequential loss of myelin proteins during Wallerian degeneration in the rat spinal cord
Q90386364Serial plasma DNA levels as predictors of outcome in patients with acute traumatic cervical spinal cord injury
Q33594010Serial serum leukocyte apoptosis levels as predictors of outcome in acute traumatic brain injury
Q36627516Significant correlation between cerebrospinal fluid nitric oxide concentrations and neurologic prognosis in incomplete cervical cord injury.
Q34679913Skin-derived precursors generate myelinating Schwann cells that promote remyelination and functional recovery after contusion spinal cord injury.
Q80548042Spatiotemporal expression of Dexras1 after spinal cord transection in rats
Q47931237Spatiotemporal patterns and essential role of TNF receptor-associated factor 5 expression after rat spinal cord Injury
Q27026103Sphingolipids in spinal cord injury
Q35002788Spinal cord contusion models
Q43170523Spinal cord decompression reduces rat neural cell apoptosis secondary to spinal cord injury
Q77403293Spinal cord injury in the rat
Q46943223Spinal cord injury is accompanied by chronic progressive demyelination.
Q48291049Spinal cord injury: bridging the lesion and the role of neurotrophic factors in repair.
Q37765474Stem cell therapies for spinal cord injury
Q46158053Stem cells downregulate the elevated levels of tissue plasminogen activator in rats after spinal cord injury
Q49940089Stem cells for spinal cord injuries bearing translational potential.
Q34482689Stem cells for spinal cord regeneration: Current status
Q34098199Strategies for spinal cord injury repair.
Q38679487Subacute Posttraumatic Ascending Myelopathy After an Incomplete Spinal Cord Injury from a Gunshot Wound to the Spine: Case Report and Review of the Literature
Q91667640Subacute Traumatic Ascending Myelopathy in a 28-Year-Old Man: A Rare Case
Q30240006Subacute posttraumatic ascending myelopathy: a literature review
Q34385981Survival, Differentiation, and Migration of High-Purity Mouse Embryonic Stem Cell-derived Progenitor Motor Neurons in Fibrin Scaffolds after Sub-Acute Spinal Cord Injury
Q28741573Syndromics: a bioinformatics approach for neurotrauma research
Q43630109Synthesis and evaluation of a difluoromethylene analogue of sphingomyelin as an inhibitor of sphingomyelinase
Q27001059T cells in the central nervous system: messengers of destruction or purveyors of protection?
Q36985378TLR4 Deficiency Impairs Oligodendrocyte Formation in the Injured Spinal Cord
Q36415334TNFalpha-induced AMPA-receptor trafficking in CNS neurons; relevance to excitotoxicity?
Q81677601Targeted expression of anti-apoptotic protein p35 in oligodendrocytes reduces delayed demyelination and functional impairment after spinal cord injury
Q48597439Tauroursodeoxycholic acid alleviates secondary injury in the spinal cord via up-regulation of CIBZ gene.
Q44538522Temporal and spatial distribution of activated caspase-3 after subdural kainic acid infusions in rat spinal cord
Q48226697Temporal-spatial dynamics in oligodendrocyte and glial progenitor cell numbers throughout ventrolateral white matter following contusion spinal cord injury
Q36499206Temporospatial expression of fibulin-1 after acute spinal cord injury in rats
Q41575599The Effects of Difumarate Salt S-15176 after Spinal Cord Injury in Rats
Q37618338The Function of FGFR1 Signalling in the Spinal Cord: Therapeutic Approaches Using FGFR1 Ligands after Spinal Cord Injury
Q34442409The JNK- and AKT/GSK3β- signaling pathways converge to regulate Puma induction and neuronal apoptosis induced by trophic factor deprivation
Q27863415The LTB4-BLT1 axis mediates neutrophil infiltration and secondary injury in experimental spinal cord injury
Q37781898The Pathogenesis and Treatment of Acute Spinal Cord Injuries in Dogs
Q38598334The Role of Therapeutic Hypothermia After Traumatic Spinal Cord Injury--A Systematic Review
Q37523956The cancer drug tamoxifen: a potential therapeutic treatment for spinal cord injury
Q57212868The combined effect of granulocyte-colony stimulating factor (G-CSF) treatment and exercise in rats with spinal cord injury
Q42376420The combined strategy of mesenchymal stem cells and tissue-engineered scaffolds for spinal cord injury regeneration
Q33685823The complement cascade: Yin-Yang in neuroinflammation--neuro-protection and -degeneration
Q36735140The cyclin-dependent kinase inhibitor p57kip2 is a negative regulator of Schwann cell differentiation and in vitro myelination.
Q92745530The fate and function of oligodendrocyte progenitor cells after traumatic spinal cord injury
Q37118012The importance of NAD in multiple sclerosis
Q27320717The multifaceted effects of agmatine on functional recovery after spinal cord injury through Modulations of BMP-2/4/7 expressions in neurons and glial cells
Q36317961The potential for cellular therapy combined with growth factors in spinal cord injury
Q34745966The prevalence and phenotype of activated microglia/macrophages within the spinal cord of the hyperostotic mouse (twy/twy) changes in response to chronic progressive spinal cord compression: implications for human cervical compressive myelopathy
Q36520580The reactions and role of NG2 glia in spinal cord injury
Q38061012The retina as a window to the brain-from eye research to CNS disorders
Q48416693The role of RhoA in retrograde neuronal death and axon regeneration after spinal cord injury.
Q37433757The role of inducible nitric oxide synthase following spinal cord injury in rat.
Q47640776The role of the miR-99b-5p/mTOR signaling pathway in neuroregeneration in mice following spinal cord injury
Q48305269The role of voltage-gated Ca2+ channels in anoxic injury of spinal cord white matter
Q35044629The temporal and spatial profiles of cell loss following experimental spinal cord injury: effect of antioxidant therapy on cell death and functional recovery.
Q21089854The therapeutic profile of rolipram, PDE target and mechanism of action as a neuroprotectant following spinal cord injury
Q34118301Theiler's virus infection: Pathophysiology of demyelination and neurodegeneration.
Q26749447Therapeutic Effects of Traditional Chinese Medicine on Spinal Cord Injury: A Promising Supplementary Treatment in Future
Q36542728Therapeutic interventions after spinal cord injury.
Q33933379Thoracic rat spinal cord contusion injury induces remote spinal gliogenesis but not neurogenesis or gliogenesis in the brain
Q51736036Three dimensional electron microscopy reveals changing axonal and myelin morphology along normal and partially injured optic nerves.
Q35116558Tight squeeze, slow burn: inflammation and the aetiology of cervical myelopathy
Q35102824To die or not to die for neurons in ischemia, traumatic brain injury and epilepsy: a review on the stress-activated signaling pathways and apoptotic pathways
Q50940964Tolerability and efficacy of erythropoietin (EPO) treatment in traumatic spinal cord injury: a preliminary randomized comparative trial vs. methylprednisolone (MP).
Q27306821Topiramate treatment is neuroprotective and reduces oligodendrocyte loss after cervical spinal cord injury
Q34004263Topography of neuron loss in the retinal ganglion cell layer in human glaucoma
Q31004909Topological data analysis for discovery in preclinical spinal cord injury and traumatic brain injury.
Q42200227Transduction efficiency of neurons and glial cells by AAV-1, -5, -9, -rh10 and -hu11 serotypes in rat spinal cord following contusion injury
Q37712579Transplantation of PDGF-AA-Overexpressing Oligodendrocyte Precursor Cells Promotes Recovery in Rat Following Spinal Cord Injury
Q33720720Transplantation of ciliary neurotrophic factor-expressing adult oligodendrocyte precursor cells promotes remyelination and functional recovery after spinal cord injury.
Q30490845Transplantation of human neural stem cells transduced with Olig2 transcription factor improves locomotor recovery and enhances myelination in the white matter of rat spinal cord following contusive injury
Q37763613Transplantation of umbilical cord blood stem cells for treating spinal cord injury
Q37576550Transplantation-mediated strategies to promote axonal regeneration following spinal cord injury.
Q64061191Traumatic Spinal Cord Injury: An Overview of Pathophysiology, Models and Acute Injury Mechanisms
Q38315209Traumatic injury induces differential expression of cell death genes in organotypic brain slice cultures determined by complementary DNA array hybridization
Q43807452Traumatic injury-induced BMP7 expression in the adult rat spinal cord
Q37574857Treadmill exercise reduces spinal cord injury-induced apoptosis by activating the PI3K/Akt pathway in rats
Q74411614Tumor necrosis factor receptor deletion reduces nuclear factor-kappaB activation, cellular inhibitor of apoptosis protein 2 expression, and functional recovery after traumatic spinal cord injury
Q36312720Umbilical cord blood stem cell mediated downregulation of fas improves functional recovery of rats after spinal cord injury
Q28078778Understanding the NG2 Glial Scar after Spinal Cord Injury
Q38713422Unique spectral signatures of the nucleic acid dye acridine orange can distinguish cell death by apoptosis and necroptosis.
Q78709741Upregulation of phospholipase D1 in the spinal cords of rats with clip compression injury
Q47961640Using Retinal Imaging to Study Dementia
Q79080347Vaccination with dendritic cells pulsed with peptides of myelin basic protein promotes functional recovery from spinal cord injury
Q44554982Vascular endothelial growth factor improves functional outcome and decreases secondary degeneration in experimental spinal cord contusion injury
Q35232779Wallerian degeneration: gaining perspective on inflammatory events after peripheral nerve injury
Q34939468White matter changes linked to visual recovery after nerve decompression
Q37876560Will stem cell therapies be safe and effective for treating spinal cord injuries?
Q41233374Zbtb38 is a novel target for spinal cord injury.
Q27009439microRNAs in spinal cord injury: potential roles and therapeutic implications
Q45329398p53- and Bax-mediated apoptosis in injured rat spinal cord
Q33971766p75 neurotrophin receptor signaling: mechanisms for neurotrophic modulation of cell stress?

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