Stimulation of platelet activation and aggregation by a carboxyl-terminal peptide from thrombospondin binding to the integrin-associated protein receptor

scientific article published on 01 January 1997

Stimulation of platelet activation and aggregation by a carboxyl-terminal peptide from thrombospondin binding to the integrin-associated protein receptor is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.272.2.1323
P698PubMed publication ID8995439

P2093author name stringR F Thorne
G F Burns
J V Fecondo
D J Dorahy
P2860cites workPhosphorylation of human pleckstrin on Ser-113 and Ser-117 by protein kinase CQ24336180
Molecular cloning of integrin-associated protein: an immunoglobulin family member with multiple membrane-spanning domains implicated in alpha v beta 3-dependent ligand bindingQ24673765
Integrin-associated protein: a 50-kD plasma membrane antigen physically and functionally associated with integrinsQ24678607
Integrin-associated protein is a receptor for the C-terminal domain of thrombospondinQ28272569
Integrins: a family of cell surface receptorsQ28288125
Constructing proteins by dovetailing unprotected synthetic peptides: backbone-engineered HIV proteaseQ34554337
Role of thrombospondin in platelet aggregationQ34619920
Entactin stimulates neutrophil adhesion and chemotaxis through interactions between its Arg-Gly-Asp (RGD) domain and the leukocyte response integrinQ35612919
Cell attachment to thrombospondin: the role of ARG-GLY-ASP, calcium, and integrin receptorsQ36221030
Leukocyte response integrin and integrin-associated protein act as a signal transduction unit in generation of a phagocyte respiratory burstQ36362394
Biological activities of peptides and peptide analogues derived from common sequences present in thrombospondin, properdin, and malarial proteinsQ36530718
ThrombospondinsQ36689844
Complex formation of platelet thrombospondin with fibrinogenQ36985923
A monoclonal antibody against human thrombospondin inhibits platelet aggregationQ37688937
Identification of a new class of inducible receptors on platelets. Thrombospondin interacts with platelets via a GPIIb-IIIa-independent mechanismQ40920150
Thrombospondin mediates calcium mobilization in fibroblasts via its Arg-Gly-Asp and carboxyl-terminal domainsQ41283869
Thrombospondin sequence motif (CSVTCG) is responsible for CD36 bindingQ41640029
A radioimmunoassay for thrombospondin, used in a comparative study of thrombospondin, beta-thromboglobulin and platelet factor 4 in healthy volunteers.Q46785316
Thrombospondin is the endogenous lectin of human plateletsQ59084076
Thrombospondin binds normally to glycoprotein IIIb deficient plateletsQ67700491
Secreted platelet thrombospondin binds monovalently to platelets and erythrocytes in the absence of free Ca2+Q70464486
Antibodies against a 23Kd heparin binding fragment of thrombospondin inhibit platelet aggregationQ70667344
Topographical Association of the Platelet Fc-receptor with the Glycoprotein IIb-IIIa ComplexQ82276445
Heterogeneity of Platelet Fc-receptor-dependent Response to Activating Monoclonal AntibodiesQ82276653
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)1323-1330
P577publication date1997-01-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleStimulation of platelet activation and aggregation by a carboxyl-terminal peptide from thrombospondin binding to the integrin-associated protein receptor
P478volume272

Reverse relations

cites work (P2860)
Q28299726Activation of CD47 receptors causes proliferation of human astrocytoma but not normal astrocytes via an Akt-dependent pathway
Q37744822Anti-leukemic activity and tolerability of anti-human CD47 monoclonal antibodies
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Q33853953CD47 and TLR-2 cross-talk regulates neutrophil transmigration
Q37043634CD47 gene knockout protects against transient focal cerebral ischemia in mice
Q36771076CD47 signaling pathways controlling cellular differentiation and responses to stress
Q28270624CD47 update: a multifaceted actor in the tumour microenvironment of potential therapeutic interest
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Q42727595Glucose Regulation of Thrombospondin and Its Role in the Modulation of Smooth Muscle Cell Proliferation
Q92470683Immune checkpoint-based therapy in myeloid malignancies: a promise yet to be fulfilled
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Q35853521Lewis Y antigen modified CD47 is an independent risk factor for poor prognosis and promotes early ovarian cancer metastasis
Q36973621Maps of open chromatin highlight cell type-restricted patterns of regulatory sequence variation at hematological trait loci
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Q93009443Neutrophil-Mediated Proteolysis of Thrombospondin-1 Promotes Platelet Adhesion and String Formation
Q44518910Platelet aggregation induced by the C-terminal peptide of thrombospondin-1 requires the docking protein LAT but is largely independent of alphaIIb/beta3.
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Q36384766Thrombospondin-1 stimulates platelet aggregation by blocking the antithrombotic activity of nitric oxide/cGMP signaling
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