Thrombin stimulates proliferation of liver fat-storing cells and expression of monocyte chemotactic protein-1: potential role in liver injury

scientific article published on 01 September 1995

Thrombin stimulates proliferation of liver fat-storing cells and expression of monocyte chemotactic protein-1: potential role in liver injury is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/HEP.1840220314
P698PubMed publication ID7657283

P50authorFabio MarraQ37841541
P2093author name stringValente AJ
Grandaliano G
Abboud HE
P2860cites workMolecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activationQ24337851
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
The structure of a complex of recombinant hirudin and human alpha-thrombinQ27684792
A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomasQ28116420
Thrombin stimulates proliferation of cultured rat aortic smooth muscle cells by a proteolytically activated receptorQ30449306
Significance of intravascular coagulation and fibrinolysis in acute hepatic failureQ33466813
Cultured human liver fat-storing cells produce monocyte chemotactic protein-1. Regulation by proinflammatory cytokines.Q33904041
Extracellular matrix gene expression increases preferentially in rat lipocytes and sinusoidal endothelial cells during hepatic fibrosis in vivoQ34263631
Experimental hepatic necrosis: Studies on coagulation abnormalities, plasma clearance, and organ distribution of 125I-labelled fibrinogenQ34476449
Activation of cultured rat hepatic lipocytes by Kupffer cell conditioned medium. Direct enhancement of matrix synthesis and stimulation of cell proliferation via induction of platelet-derived growth factor receptorsQ34580643
Effects of platelet-derived growth factor and other polypeptide mitogens on DNA synthesis and growth of cultured rat liver fat-storing cellsQ34580695
"Mirror image" antagonists of thrombin-induced platelet activation based on thrombin receptor structureQ35597476
Enhancement of incisional wound healing and neovascularization in normal rats by thrombin and synthetic thrombin receptor-activating peptidesQ35601886
Synthetic alpha-thrombin receptor peptides activate G protein-coupled signaling pathways but are unable to induce mitogenesisQ37370158
Hepatic lipocytes: the principal collagen-producing cells of normal rat liverQ37558514
Cell mediated events that control blood coagulation and vascular injuryQ40800548
Thrombin in inflammation and healing: relevance to rheumatoid arthritis.Q40815910
Fat-storing cells as liver-specific pericytes. Spatial dynamics of agonist-stimulated intracellular calcium transientsQ41020565
Specificity of the thrombin receptor for agonist peptide is defined by its extracellular surfaceQ41474475
Retinoic acid suppresses the response to platelet-derived growth factor in human hepatic Ito-cell-like myofibroblasts: a post-receptor mechanism independent of raf/fos/jun/egr activationQ41913191
Phenotypical modulation of liver fat-storing cells by retinoids. Influence on unstimulated and growth factor-induced cell proliferationQ42458330
Regulation of macrophage colony-stimulating factor in liver fat-storing cells by peptide growth factorsQ42460146
Biosynthesis of platelet-activating factor and its 1O-acyl analogue by liver fat-storing cellsQ42500564
Quantitative analysis of proliferating sinusoidal cells in dimethylnitrosamine-induced cirrhosis. An immunohistochemical studyQ45151451
Lipocyte activation and hepatic fibrosisQ68100736
Purification of a monocyte chemotactic factor secreted by nonhuman primate vascular cells in cultureQ68501743
Hepatic sinusoidal cell destruction in the development of intravascular coagulation in acute liver failure of ratsQ69667566
Activation of blood coagulation in Crohn's disease. Increased plasma fibrinopeptide A levels and enhanced generation of monocyte tissue factor activityQ69691382
Identification of monocyte chemotactic activity produced by malignant cellsQ69731360
Early and intensive therapy of intravascular coagulation in acute liver failureQ70033663
Characterization of monocyte chemotactic protein-1 binding to human monocytesQ70140841
Regulation of extracellular matrix synthesis by transforming growth factor beta 1 in human fat-storing cellsQ70767689
Monocyte chemotaxis: stimulation by specific exosite region in thrombinQ71695951
Long-term effects of thrombin require sustained activation of the functional thrombin receptorQ72565417
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectchemotaxisQ658145
P304page(s)780-787
P577publication date1995-09-01
P1433published inHepatologyQ15724398
P1476titleThrombin stimulates proliferation of liver fat-storing cells and expression of monocyte chemotactic protein-1: potential role in liver injury
P478volume22