Reduction in the toxicity of aminopterin--monoclonal-antibody conjugates by leucovorin

scientific article published on 01 August 1994

Reduction in the toxicity of aminopterin--monoclonal-antibody conjugates by leucovorin is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/BF01525319
P698PubMed publication ID8044832

P2093author name stringG A Pietersz
A J Rowland
P2860cites workEstimation of the antileukemic potency of the antimetabolite aminopterin, administered alone and in combination with citrovorum factor or folic acidQ57153766
Eradication Of Leukaemic Cells (L1210) by Methotrexate and Methotrexate Plus Citrovorum FactorQ59048765
Biodistribution and tumour localization of a methotrexate-monoclonal-antibody 791T/36 conjugate in nude mice with human tumour xenograftsQ68366944
Anti-tumour activity of aminopterin-monoclonal antibody conjugates; in vitro and in vivo comparison with methotrexate-monoclonal antibody conjugatesQ68838535
Alloantigenic phenotype of radiation-induced thymomas in the mouseQ72532752
Monoclonal antibodies to the murine Ly-2.1 cell surface antigenQ72665266
The relation of folic acid reductase to aminopterin toxicityQ76419865
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Antibody conjugates for the treatment of cancerQ35595959
Antibodies as drug carriers for solid tumors: evaluation of drug-anti-SSEA-1 conjugates in the treatment of teratocarcinoma.Q37615757
Isolation of pure IgG1, IgG2a and IgG2b immunoglobulins from mouse serum using protein A-SepharoseQ39218339
Drug-monoclonal antibody conjugates for cancer therapy: potentials and limitationsQ39548934
Studies with high-dose methotrexate--historical backgroundQ39720529
The clinical pharmacology of methotrexateQ40149030
High-dose methotrexate in osteogenic sarcoma: a 5-year experienceQ40876967
Interaction of methotrexate polyglutamates and dihydrofolate during leucovorin rescue in a human breast cancer cell line (MCF-7)Q41731102
Methotrexate therapy of head and neck cancer: improvement in therapeutic index by the use of leucovorin "rescue".Q42231342
Improved therapeutic index with high-dose methotrexate: comparison of thymidine-purine rescue with citrovorum factor rescue in mice.Q48661724
Effect of delayed administration of citrovorum factor on the antileukemic effectiveness of aminopterin in miceQ57153762
P433issue2
P921main subjectmonoclonal antibodyQ422248
P304page(s)135-139
P577publication date1994-08-01
P1433published inCancer Immunology, ImmunotherapyQ5031409
P1476titleReduction in the toxicity of aminopterin--monoclonal-antibody conjugates by leucovorin
P478volume39