Safety, immunogenicity, and efficacy of live attenuated Vibrio cholerae O139 vaccine prototype

scientific article published on 01 April 1995

Safety, immunogenicity, and efficacy of live attenuated Vibrio cholerae O139 vaccine prototype is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0140-6736(95)90698-3
P698PubMed publication ID7715293

P2093author name stringJ J Mekalanos
D T Beattie
D R Spriggs
M K Waldor
D N Taylor
J C Sadoff
T S Coster
K P Killeen
J R Kenner
A Trofa
P2860cites workEmergence of a new cholera pandemic: molecular analysis of virulence determinants in Vibrio cholerae O139 and development of a live vaccine prototypeQ30420490
The Vibrio cholerae O139 serogroup antigen includes an O-antigen capsule and lipopolysaccharide virulence determinantsQ35912594
CTX genetic element encodes a site-specific recombination system and an intestinal colonization factor.Q36262564
Live bacterial vaccines: environmental aspectsQ40534875
Cholera vaccines: fighting an ancient scourgeQ40695834
Field trial of oral cholera vaccines in Bangladesh: serum vibriocidal and antitoxic antibodies as markers of the risk of cholera.Q54695943
Large outbreak of clinical cholera due to Vibrio cholerae non-O1 in BangladeshQ57924349
Development of a live, oral, attenuated vaccine against El Tor choleraQ57924437
Serologic Differentiation Between Antitoxin Responses to Infection with Vibrio cholerae and Enterotoxin-Producing Escherichia coliQ57925766
Magnitude, kinetics, and duration of vibriocidal antibody responses in North Americans after ingestion of Vibrio choleraeQ70313647
O-antigenic lipopolysaccharide of Vibrio cholerae O139 Bengal, a new epidemic strain for recent cholera in the Indian subcontinentQ71600875
Emergence of novel strain of Vibrio cholerae with epidemic potential in southern and eastern IndiaQ72212989
Non-O1 Vibrio choleraeQ72227351
Vibrio cholerae O139 specific gene sequencesQ72677766
P433issue8955
P407language of work or nameEnglishQ1860
P921main subjectvaccineQ134808
Vibrio choleraeQ160821
attenuated vaccineQ1810913
P304page(s)949-952
P577publication date1995-04-01
P1433published inThe LancetQ939416
P1476titleSafety, immunogenicity, and efficacy of live attenuated Vibrio cholerae O139 vaccine prototype
P478volume345

Reverse relations

cites work (P2860)
Q30370187A defined transposon mutant library and its use in identifying motility genes in Vibrio cholerae.
Q35609627A new type of conjugative transposon encodes resistance to sulfamethoxazole, trimethoprim, and streptomycin in Vibrio cholerae O139.
Q33752525A recombinant live attenuated strain of Vibrio cholerae induces immunity against tetanus toxin and Bordetella pertussis tracheal colonization factor.
Q39877153Accessory human cytomegalovirus glycoprotein US9 in the unique short component of the viral genome promotes cell-to-cell transmission of virus in polarized epithelial cells
Q33975799Active immunization in the United States: developments over the past decade
Q35499586Alterations in Vibrio cholerae motility phenotypes correlate with changes in virulence factor expression.
Q35464775Antibody against the capsule of Vibrio cholerae O139 protects against experimental challenge
Q39516986Association of protease activity in Vibrio cholerae vaccine strains with decreases in transcellular epithelial resistance of polarized T84 intestinal epithelial cells
Q29346616Characterization of enhancer binding by the Vibrio cholerae flagellar regulatory protein FlrC
Q73620155Cholera
Q30235247Cholera.
Q35548775Coexpression of the B subunit of Shiga toxin 1 and EaeA from enterohemorrhagic Escherichia coli in Vibrio cholerae vaccine strains
Q39830834Comparison of immune responses in patients infected with Vibrio cholerae O139 and O1.
Q78862034Construction and characterisation of O139 cholera vaccine candidates
Q39825901Construction and characterization of a potential live oral carrier-based vaccine against Vibrio cholerae O139.
Q35088006Construction and evaluation of V. cholerae O139 mutant, VCUSM21P, as a safe live attenuated cholera vaccine
Q46652410Construction and evaluation of a O139 Vibrio cholerae vaccine candidate based on a hemA gene mutation
Q36480147Construction of a Vibrio cholerae prototype vaccine strain O395-N1-E1 which accumulates cell-associated cholera toxin B subunit
Q34005028Construction of a Vibrio cholerae vaccine candidate using transposon delivery and FLP recombinase-mediated excision
Q36483642Decreased potency of the Vibrio cholerae sheathed flagellum to trigger host innate immunity
Q35469131Development of Shigella sonnei live oral vaccines based on defined rfbInaba deletion mutants of Vibrio cholerae expressing the Shigella serotype D O polysaccharide.
Q35526942Development of a germfree mouse model of Vibrio cholerae infection.
Q39518093Differential interleukin-8 response of intestinal epithelial cell line to reactogenic and nonreactogenic candidate vaccine strains of Vibrio cholerae
Q33722821Differential regulation of multiple flagellins in Vibrio cholerae
Q34009225Diminished diarrheal response to Vibrio cholerae strains carrying the replicative form of the CTX(Phi) genome instead of CTX(Phi) lysogens in adult rabbits
Q30449794Enteric bacterial toxins: mechanisms of action and linkage to intestinal secretion
Q64074204Flagellar Synthesis
Q33996336Flagellum-independent surface migration of Vibrio cholerae and Escherichia coli
Q36191950Going against the grain: chemotaxis and infection in Vibrio cholerae
Q30432626Identification of a vibrio cholerae RTX toxin gene cluster that is tightly linked to the cholera toxin prophage
Q36898523Immunization with Vibrio cholerae outer membrane vesicles induces protective immunity in mice.
Q28485730In vivo covalent cross-linking of cellular actin by the Vibrio cholerae RTX toxin
Q36227993Induction of interleukin-8 in T84 cells by Vibrio cholerae.
Q36422323Lipidation of an FlrC-dependent protein is required for enhanced intestinal colonization by Vibrio cholerae
Q36970778Lipopolysaccharide modifications of a cholera vaccine candidate based on outer membrane vesicles reduce endotoxicity and reveal the major protective antigen.
Q36993624Metalloprotease vsm is the major determinant of toxicity for extracellular products of Vibrio splendidus
Q40695423New developments in the understanding of cholera
Q37953796New-generation vaccines against cholera
Q24235775Oral vaccines for preventing cholera
Q40015233PCR-based detection of Vibrio cholerae O139 Bengal with sequences encoding glycosyltransferases
Q33732722Pathogenic and vaccine significance of toxin-coregulated pili of Vibrio cholerae E1 Tor.
Q30328099Preparation, immunogenicity, and protective efficacy, in a murine model, of a conjugate vaccine composed of the polysaccharide moiety of the lipopolysaccharide of Vibrio cholerae O139 bound to tetanus toxoid
Q36670147Production and sequence validation of a complete full length ORF collection for the pathogenic bacterium Vibrio cholerae
Q30363424Prolonged colonization of mice by Vibrio cholerae El Tor O1 depends on accessory toxins
Q34033623Reduction in capsular content and enhanced bacterial susceptibility to serum killing of Vibrio cholerae O139 associated with the 2002 cholera epidemic in Bangladesh
Q33942939Sensitive microplate assay for detection of bactericidal antibodies to Vibrio cholerae O139
Q34246068Social and news media enable estimation of epidemiological patterns early in the 2010 Haitian cholera outbreak
Q39290834Structural and functional importance of outer membrane proteins in Vibrio cholerae flagellum.
Q33998373Susceptibility of Vibrio cholerae O139 to antibody-dependent, complement-mediated bacteriolysis
Q37481380The Vibrio cholerae flagellar regulatory hierarchy controls expression of virulence factors
Q24614429The incubation period of cholera: a systematic review
Q37523806The utility of human challenge studies in vaccine development: lessons learned from cholera
Q34757562Transcriptional responses of intestinal epithelial cells to infection with Vibrio cholerae
Q39514280Use of lambda phage S and R gene products in an inducible lysis system for Vibrio cholerae- and Salmonella enterica serovar typhimurium-based DNA vaccine delivery systems
Q30332762Vibrio cholerae O139 Bengal: odyssey of a fortuitous variant
Q33598485Vibrio cholerae O139 conjugate vaccines: synthesis and immunogenicity of V. cholerae O139 capsular polysaccharide conjugates with recombinant diphtheria toxin mutant in mice
Q30882964Vibrio cholerae cytolysin causes an inflammatory response in human intestinal epithelial cells that is modulated by the PrtV protease
Q34562952Vibrio cholerae: lessons for mucosal vaccine design
Q35229428Vibriocidal antibody responses in North American volunteers exposed to wild-type or vaccine Vibrio cholerae O139: specificity and relevance to immunity

Search more.