Telomerase: immortality enzyme or oncogene?

scientific article published on 01 February 1995

Telomerase: immortality enzyme or oncogene? is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/NG0295-104
P698PubMed publication ID7719331

P2093author name stringKipling D
P2860cites workSpecific Association of Human Telomerase Activity with Immortal Cells and CancerQ27860801
Telomeres shorten during ageing of human fibroblastsQ29547357
Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activityQ29615388
Telomere length predicts replicative capacity of human fibroblastsQ29615745
Cell cycle control and cancerQ29617536
Telomere reduction in human colorectal carcinoma and with ageingQ34037761
The effects of nucleoside analogs on telomerase and telomeres in TetrahymenaQ34810908
Telomerase activity in human ovarian carcinomaQ35142569
Lethality induced by a single site-specific double-strand break in a dispensable yeast plasmidQ36366668
Restoration of telomeres in human papillomavirus-immortalized human anogenital epithelial cellsQ36645358
Fidelity of mitotic chromosome transmissionQ37056951
Why are human cells resistant to malignant cell transformation in vitro?Q40798787
Subtelomeric as well as telomeric sequences are lost from chromosomes in proliferating B lymphocytesQ41563204
Significant telomere shortening in childhood leukemiaQ45099372
Detection of somatic changes in human renal cell carcinomas with oligonucleotide probes specific for simple repeat motifsQ53482878
Telomere end-replication problem and cell agingQ56508218
In vivo loss of telomeric repeats with age in humansQ68048615
Telomere length variation in normal and malignant human tissuesQ71670309
Telomeric associations and loss of telomeric DNA repeats in renal tumorsQ72076160
P433issue2
P304page(s)104-106
P577publication date1995-02-01
P1433published inNature GeneticsQ976454
P1476titleTelomerase: immortality enzyme or oncogene?
P478volume9

Reverse relations

cites work (P2860)
Q86630527Age-associated decreases in human DNA repair capacity: Implications for the skin
Q78880907An analysis of replicative senescence in dermal fibroblasts derived from chronic leg wounds predicts that telomerase therapy would fail to reverse their disease-specific cellular and proteolytic phenotype
Q41171480Cell senescence and a mechanism of clonal evolution leading to continuous cell proliferation, loss of heterozygosity, and tumor heterogeneity: studies on two immortal colon cancer cell lines.
Q42715561Do telomerase antagonists represent a novel anti-cancer strategy?
Q39479842Human telomerase reverse transcriptase-immortalized porcine monomyeloid cell lines for the production of porcine reproductive and respiratory syndrome virus
Q55283648Inhibitory effects of dietary protocatechuic acid and costunolide on 7,12-dimethylbenz[a]anthracene-induced hamster cheek pouch carcinogenesis.
Q52892198Interactive effects of methyl-deficiency and dietary restriction on liver cell proliferation and telomerase activity in Fischer 344 rats pretreated with aflatoxin B(1).
Q41610038Mammalian Telomerase: Catalytic Subunit and Knockout Mice
Q33822119Melanoma: Stem cells, sun exposure and hallmarks for carcinogenesis, molecular concepts and future clinical implications
Q41057265Preferential Accumulation of Single-Stranded Regions in Telomeres of Human Fibroblasts
Q73853725Telomerase Activity in Human Benign Prostate Tissue and Prostatic Adenocarcinomas
Q71086930Telomerase activity of normal tissues and neoplasms in rat colon carcinogenesis induced by methylazoxymethanol acetate and its difference from that of human colonic tissues
Q34538689Telomerase and telomeres: from basic biology to cancer treatment
Q41738285Telomerase: Putting an End to DNA
Q92701873Telomere Abnormalities in the Pathobiology of Idiopathic Pulmonary Fibrosis
Q41583676Telomere structure and telomerase expression during mouse development and tumorigenesis
Q34224763Telomeres, replicative senescence and human ageing

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