The effects of bile salts and lipids on the physicochemical behavior of gemfibrozil

scientific article published on 01 December 1994

The effects of bile salts and lipids on the physicochemical behavior of gemfibrozil is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1023/A:1018967401000
P698PubMed publication ID7899240

P2093author name stringS R Babu
P E Luner
G W Radebaugh
P2860cites workTHE FUNCTION OF BILE SALTS IN FAT ABSORPTION. THE SOLVENT PROPERTIES OF DILUTE MICELLAR SOLUTIONS OF CONJUGATED BILE SALTSQ24532169
THE INTRALUMINAL PHASE OF FAT DIGESTION IN MAN: THE LIPID CONTENT OF THE MICELLAR AND OIL PHASES OF INTESTINAL CONTENT OBTAINED DURING FAT DIGESTION AND ABSORPTIONQ24623308
Influence of food and diet on gastrointestinal drug absorption: a reviewQ39669439
Mechanisms of Surfactant Effects on Drug AbsorptionQ39989790
Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 2. Phase analysis and aggregation states of luminal lipids during duodenal fat digestion in healthy adult human beingsQ41228115
Light-Scattering Studies on Bile Acid Salts I: Pattern of Self-Association of Sodium Cholate, Sodium Glycocholate, and Sodium Taurocholate in Aqueous Electrolyte SolutionsQ45027853
Upper gastrointestinal (GI) pH in young, healthy men and women.Q51615125
Analysis of conjugated and unconjugated bile acids in serum and jejunal fluid of normal subjects.Q51632704
Interaction of drugs with bile components. I. Effects of bile salts on the dissolution behavior of indomethacin and phenylbutazoneQ66984826
Intestinal absorption of griseofulvin from a triolein digestion mixture in ratsQ67343231
Solubilization and dissolution properties of a leukotriene-D4 antagonist in micellar solutionsQ67559210
Partition of lipids between emulsified oil and micellar phases of glyceride-bile salt dispersionsQ72306569
Properties of fatty acids in dispersions of emulsified lipid and bile salt and the significance of these properties in fat absorption in the pig and the sheepQ72511583
Solubilizing properties of bile salt solutions. II. Effect of inorganic electrolyte, lipids, and a mixed bile salt system on solubilization of glutethimide, griseofulvin, and hexestrolQ72798646
Solubilizing properties of bile salt solutions. I. Effect of temperature and bile salt concentration on solubilization of glutethimide, griseofulvin, and hexestrolQ72810933
Physico-chemical state of lipids in intestinal content during their digestion and absorptionQ79410895
Modification of intestinal absorption of drugs by lipoidal adjuvantsQ86839112
P433issue12
P921main subjectlipidQ11367
P304page(s)1755-1760
P577publication date1994-12-01
P1433published inPharmaceutical ResearchQ7180737
P1476titleThe effects of bile salts and lipids on the physicochemical behavior of gemfibrozil
P478volume11

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cites work (P2860)
Q32079756Chromatographic retention of drug molecules on immobilised liposomes prepared from egg phospholipids and from chemically pure phospholipids
Q42638823Direct estimation of the in vivo dissolution of spironolactone, in two particle size ranges, using the single-pass perfusion technique (Loc-I-Gut) in humans
Q33747102Effects of food on clinical pharmacokinetics
Q41060497Gemfibrozil. A reappraisal of its pharmacological properties and place in the management of dyslipidaemia
Q34384372In vitro assessment of oral lipid based formulations
Q34190317Influence of physicochemical properties on dissolution of drugs in the gastrointestinal tract
Q50754829Membrane transport of drugs in different regions of the intestinal tract of the rat.
Q41364364Physiochemical and physiological mechanisms for the effects of food on drug absorption: the role of lipids and pH.
Q77364374Some relationships between the physical properties of various 3-acyloxymethyl prodrugs of phenytoin to structure: potential in vivo performance implications
Q34088713Surface active drugs: self-association and interaction with membranes and surfactants. Physicochemical and biological aspects

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