Cancer prognostics: past, present and p27

scientific article published on 01 February 1997

Cancer prognostics: past, present and p27 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NM0297-152
P698PubMed publication ID9018230

P2093author name stringP S Steeg
J S Abrams
P2860cites workLaser capture microdissectionQ28293867
Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumorsQ29616203
Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27Q29617346
Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).Q34381917
Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancerQ34415244
Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas.Q34415250
Translational control of p27Kip1 accumulation during the cell cycleQ41213467
To affinity ... and beyond!Q71835102
c-erbB-2 expression and response to adjuvant therapy in women with node-positive early breast cancerQ72673347
Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patientsQ73034313
P433issue2
P304page(s)152-154
P577publication date1997-02-01
P1433published inNature MedicineQ1633234
P1476titleCancer prognostics: past, present and p27
P478volume3

Reverse relations

cites work (P2860)
Q58220589A survival-stratification model of human colorectal carcinomas with beta-catenin and p27kip1
Q38888134Aberrant expression of cell cycle regulatory genes predicts overall and disease free survival in malignant pleural mesothelioma patients.
Q40046781Adenovirus expressing mutant p27kip1 enhanced apoptosis and inhibited the growth of xenografted human breast cancer
Q45874114Adenovirus expressing p27(Kip1) induces growth arrest of lung cancer cell lines and suppresses the growth of established lung cancer xenografts
Q24552430Analysis of the complex relationship between nuclear export and aryl hydrocarbon receptor-mediated gene regulation
Q73821343Association of SYT-SSX fusion types with proliferative activity and prognosis in synovial sarcoma
Q74046042Cancer: looking outside the genome
Q41727409Clinical and molecular prognostic factors in sphincter-preserving surgery for rectal cancer
Q28138175Cyclin D1 in breast cancer
Q37242908Cyclin dependent kinase inhibitor p27Kip1 expression in normal and neoplastic cervical epithelium
Q40869174Cyclin-dependent kinase inhibitor p27(Kip1) expression in thyroid cells obtained by fine-needle aspiration biopsy: a preliminary report
Q34536470Cytoplasmic sequestration of p27 via AKT phosphorylation in renal cell carcinoma.
Q74081812Decreased immunoreactivity for cell-cycle regulator p27(Kip1) in Kaposi's sarcoma correlates with higher stage and extracutaneous involvement
Q36622949Decreasing of p27(Kip1)and cyclin E protein levels is associated with progression from superficial into invasive bladder cancer
Q28139243Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1
Q33859300Discovering novel chemotherapeutic drugs for the third millennium
Q42739357Evaluation of p53, p63, p21, p27, ki-67 in paranasal sinus squamous cell carcinoma and inverted papilloma
Q44452174Fludarabine-induced apoptosis of B chronic lymphocytic leukemia cells includes early cleavage of p27kip1 by caspases
Q34302997Gene interaction enrichment and network analysis to identify dysregulated pathways and their interactions in complex diseases
Q37229689Genetic prognostic markers in colorectal cancer
Q38148142Immunohistochemical evaluation of oral epithelial dysplasia using cyclin-D1, p27 and p63 expression as predictors of malignant transformation
Q35128610Implications of Genetic Testing in the Management of Colorectal Cancer
Q40683948Inhibitory effect of p27KIP1 gene transfer on head and neck squamous cell carcinoma cell lines
Q35202114Myc-enhanced expression of Cul1 promotes ubiquitin-dependent proteolysis and cell cycle progression
Q33545598New concepts in tissue specificity for prostate cancer and benign prostatic hyperplasia
Q57993317Overexpression of cyclin D1 and cdk4 in tumorigenesis of sporadic hepatoblastomas
Q63561085PHLPP2 stabilization by p27 mediates its inhibition of bladder cancer invasion by promoting autophagic degradation of MMP2 protein
Q47929697Prognostic impact of p27KIP1 expression in cyclin D1 positive lymphoproliferative disorders.
Q77214624Prognostic markers in rectal carcinoma
Q42461063Prostate stem cell compartments: expression of the cell cycle inhibitor p27Kip1 in normal, hyperplastic, and neoplastic cells.
Q53419140Reduced expression of p27Kip1 protein is associated with poor clinical outcome of breast cancer patients treated with systemic chemotherapy and is linked to cell proliferation and differentiation.
Q24685645Role of the F-box protein Skp2 in adhesion-dependent cell cycle progression
Q38068794Roles of the Skp2/p27 axis in the progression of chronic nephropathy
Q28137860SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27
Q34321746What we could do now: molecular pathology of colorectal cancer
Q38464269p(21WAF1/CIP1) expression in breast cancers: associations with p53 and outcome
Q73399997p27 expression and gastric carcinoma
Q28343428p27(Kip1) induction and inhibition of proliferation by the intracellular Ah receptor in developing thymus and hepatoma cells
Q73104083p27(Kip1) loss does not predict survival in patients with advanced gastric carcinoma
Q24801901p27Kip1 is expressed in proliferating cells in its form phosphorylated on threonine 187
Q33535200p27kip1: a multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers

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