Absence of p75(NTR) expression reduces nerve growth factor immunolocalization in cholinergic septal neurons

scientific article published on 01 November 2000

Absence of p75(NTR) expression reduces nerve growth factor immunolocalization in cholinergic septal neurons is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/1096-9861(20001106)427:1<54::AID-CNE4>3.0.CO;2-F
P698PubMed publication ID11042591

P50authorRebecca Jane RylettQ64856886
Keith A. CrutcherQ40334839
P2093author name stringB E Kalisch
M D Kawaja
K M Krol
P2860cites workA rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous systemQ28505213
The trk proto-oncogene encodes a receptor for nerve growth factorQ28609788
Nerve growth factor nonresponsive pheochromocytoma cells: altered internalization results in signaling dysfunctionQ28755171
Nerve growth factor mediates signal transduction through trk homodimer receptorsQ28854581
Prolonged exposure to elevated levels of endogenous nerve growth factor affects the morphological and neurochemical features of sympathetic neurons of postnatal and adult miceQ30675835
Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene.Q34338664
The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron deathQ34457074
Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF.Q34576586
Development and regional expression of beta nerve growth factor messenger RNA and protein in the rat central nervous systemQ35589318
NGF-stimulated retrograde transport of trkA in the mammalian nervous systemQ36235736
Regulation of nerve growth factor receptor gene expression in sympathetic neurons during developmentQ36235983
Rapid retrograde tyrosine phosphorylation of trkA and other proteins in rat sympathetic neurons in compartmented culturesQ36268164
Differential expression of nerve growth factor receptors leads to altered binding affinity and neurotrophin responsiveness.Q36493889
The retrograde axonal transport of nerve growth factorQ48571703
Loss of AChE- and NGFr-labeling precedes neuronal death of axotomized septal-diagonal band neurons: reversal by intraventricular NGF infusionQ48681099
NGF-Mediated increase of choline acetyltransferase (ChAT) in the neonatal rat forebrain: Evidence for a physiological role of NGF in the brain?Q48792920
In vitro Evidence for two distinct hippocampal growth factors: basis of neuronal plasticity?Q48922736
Analysis of cutaneous sensory neurons in transgenic mice lacking the low affinity neurotrophin receptor p75.Q50532678
Nerve growth factor derived from terminals selectively increases the ratio of p75 to trkA NGF receptors on mature sympathetic neurons.Q50776082
Blocking nerve growth factor binding to the p75 neurotrophin receptor on sympathetic neurons transiently reduces trkA activation but does not affect neuronal survival.Q52527387
Continuous presence of nerve growth factor is required for maintenance of cholinergic septal neurons in organotypic slice culturesQ57176433
Differential role of the low affinity neurotrophin receptor (p75) in retrograde axonal transport of the neurotrophinsQ59783976
p75NGFR and cholinergic neurons in the developing forebrain: a re-examinationQ61204161
Expression of the NGF receptor gene in sensory neurons and their cutaneous targets prior to and during innervationQ68452693
Hypertrophy of pheochromocytoma cells treated with nerve growth factor and activators of adenylate cyclaseQ69205309
Nerve growth factor (NGF) reverses axotomy-induced decreases in choline acetyltransferase, NGF receptor and size of medial septum cholinergic neuronsQ69362881
p75-deficient trigeminal sensory neurons have an altered response to NGF but not to other neurotrophinsQ70478360
Chronic intraventricular injections of nerve growth factor elevate hippocampal choline acetyltransferase activity in adult rats with partial septo-hippocampal lesionsQ71270737
Deletion of a conserved juxtamembrane sequence in Trk abolishes NGF-promoted neuritogenesisQ71988401
Estimation of nuclear population from microtome sectionsQ82126847
Regulation of nerve growth factor receptor gene expression by nerve growth factor in the developing peripheral nervous systemQ36529098
Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transectionQ37410352
Trophic factors and neuronal survivalQ38772889
The significance of retrograde axonal transport for the accumulation of systemically administered nerve growth factor (NGF) in the rat superior cervical ganglionQ39385180
Nerve growth factor (NGF) in the rat CNS: Absence of specific retrograde axonal transport and tyrosine hydroxylase induction in locus coeruleus and substantia nigraQ39542404
Distribution of nerve growth factor-like immunoreactive neurons in the adult rat brain following colchicine treatmentQ41104459
Recombinant human nerve growth factor prevents retrograde degeneration of axotomized basal forebrain cholinergic neurons in the rat.Q41152058
Septohippocampal cholinergic axonal regeneration through peripheral nerve bridges: quantification and temporal developmentQ41186726
Intraventricular NGF infusion in the mature rat brain enhances sympathetic innervation of cerebrovascular targets but fails to elicit sympathetic ingrowthQ41316837
Signalling through the neurotrophin receptor p75NTR.Q41541492
Rescue of basal forebrain cholinergic neurons after implantation of genetically modified cells producing recombinant NGF.Q41741245
Choline acetyltransferase binding to and release from membranesQ41809575
Reduction in p140-TrkA receptor protein within the nucleus basalis and cortex in Alzheimer's diseaseQ42441418
Basal forebrain neuronal loss in mice lacking neurotrophin receptor p75.Q42443413
Localization of nerve growth factor, trkA and P75 immunoreactivity in the hippocampal formation and basal forebrain of adult ratsQ42450586
Nerve growth factor (NGF)-mediated up-regulation of low-affinity NGF receptor gene expression in cultured basal forebrain cholinergic neurons from postnatal 3-day-old ratsQ42452770
p140trk mRNA marks NGF-responsive forebrain neurons: evidence that trk gene expression is induced by NGFQ42458990
Nerve growth factor differentially modulates the expression of its receptor within the CNS.Q42463685
Effects of fimbria-fornix and angular bundle transection on expression of the p75NGFR mRNA by cells in the medial septum and diagonal band of Broca: correlations with cell survival, synaptic reorganization and sproutingQ42463748
Central neuronal loss and behavioral impairment in mice lacking neurotrophin receptor p75.Q42466426
Nerve growth factor in Alzheimerʼs disease: defective retrograde transport to nucleus basalisQ42481313
P75 nerve growth factor receptor is important for retrograde transport of neurotrophins in adult cholinergic basal forebrain neuronsQ42481934
TrkA-immunoreactive profiles in the central nervous system: colocalization with neurons containing p75 nerve growth factor receptor, choline acetyltransferase, and serotoninQ42490267
Nerve growth factor receptor and choline acetyltransferase colocalization in neurons within the rat forebrain: response to fimbria-fornix transectionQ42493340
Loss of nerve growth factor receptor-containing neurons in Alzheimer's disease: a quantitative analysis across subregions of the basal forebrainQ42493514
Limbic seizures increase neuronal production of messenger RNA for nerve growth factorQ42493562
NGF receptor gene expression is decreased in the nucleus basalis in Alzheimer's diseaseQ42494079
NGF induction of NGF receptor gene expression and cholinergic neuronal hypertrophy within the basal forebrain of the adult rat.Q42494413
GABAergic and cholinergic neurons exhibit high-affinity nerve growth factor binding in rat basal forebrainQ42497938
Early nerve growth factor-induced events in developing rat septal neuronsQ42497959
Distribution and characteristics of nerve growth factor binding on cholinergic neurons of rat and monkey forebrainQ42501174
In situ hybridization detection of trkA mRNA in brain: distribution, colocalization with p75NGFR and up-regulation by nerve growth factorQ42501361
High-affinity nerve growth factor receptor (Trk) immunoreactivity is localized in cholinergic neurons of the basal forebrain and striatum in the adult rat brainQ42505736
In situ hybridization localization of choline acetyltransferase mRNA in adult rat brain and spinal cordQ42507443
Differential modulation of the cholinergic phenotype of the nucleus basalis magnocellularis neurons by applying NGF at the cell body or cortical terminal fieldsQ42528834
The low affinity NGF receptor, p75, can collaborate with each of the Trks to potentiate functional responses to the neurotrophinsQ42795990
Response of septal cholinergic neurons to axotomyQ43803448
Disruption of NGF binding to the low affinity neurotrophin receptor p75LNTR reduces NGF binding to TrkA on PC12 cellsQ44794856
Kainic acid-induced seizures stimulate increased expression of nerve growth factor mRNA in rat hippocampusQ46218145
NGF receptor reexpression and NGF-mediated cholinergic neuronal hypertrophy in the damaged adult neostriatumQ46244385
Morphological response of axotomized septal neurons to nerve growth factorQ46247799
Overexpression of nerve growth factor in skin increases sensory neuron size and modulates Trk receptor expressionQ47303845
The role of p75NTR in modulating neurotrophin survival effects in developing motoneuronsQ48228470
Coordinated expression of messenger RNAs for nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 in the rat hippocampus following transient forebrain ischemiaQ48257013
Effects of elevated levels of nerve growth factor on the septohippocampal system in transgenic miceQ48389059
Sympathetic axons surround nerve growth factor-immunoreactive trigeminal neurons: observations in mice overexpressing nerve growth factorQ48503514
Sympathetic and sensory axons invade the brains of nerve growth factor transgenic mice in the absence of p75NTR expressionQ48546430
Nerve growth factor increases choline acetyltransferase but not survival or fiber outgrowth of cultured fetal septal cholinergic neuronsQ48555966
Diabetes and axotomy-induced deficits in retrograde axonal transport of nerve growth factor correlate with decreased levels of p75LNTR protein in lumbar dorsal root ganglia.Q48564888
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)54-66
P577publication date2000-11-01
P1433published inThe Journal of Comparative NeurologyQ3186907
P1476titleAbsence of p75(NTR) expression reduces nerve growth factor immunolocalization in cholinergic septal neurons
P478volume427

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cites work (P2860)
Q42521323Amelioration of cholinergic neurons dysfunction in aged rats depends on the continuous supply of NGF.
Q33982246Dissecting the involvement of tropomyosin-related kinase A and p75 neurotrophin receptor signaling in NGF deficit-induced neurodegeneration
Q42452035Enhanced spatial memory and hippocampal long-term potentiation in p75 neurotrophin receptor knockout mice.
Q37089328Global expression of NGF promotes sympathetic axonal growth in CNS white matter but does not alter its parallel orientation
Q47599136Structural and neurochemical features of postganglionic sympathetic neurons in the superior mesenteric ganglion of spontaneously hypertensive rats