| scholarly article | Q13442814 |
| P356 | DOI | 10.4049/JIMMUNOL.165.12.7096 |
| P698 | PubMed publication ID | 11120839 |
| P2093 | author name string | K Takeda | |
| O Takeuchi | |||
| S Akira | |||
| S Sato | |||
| F Nomura | |||
| T Kawai | |||
| P F Mühlradt | |||
| P2860 | cites work | Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene | Q22299417 |
| The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens. | Q40919510 | ||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 7096-7101 | |
| P577 | publication date | 2000-12-01 | |
| P1433 | published in | Journal of Immunology | Q3521441 |
| P1476 | title | Synergy and cross-tolerance between toll-like receptor (TLR) 2- and TLR4-mediated signaling pathways | |
| P478 | volume | 165 |
| Q34583785 | A critical role for MAPK signalling pathways in the transcriptional regulation of toll like receptors |
| Q83339233 | A global analysis of cross-talk in a mammalian cellular signalling network |
| Q41470245 | A plague on host defense |
| Q30946997 | A toll-like receptor (TLR) gene that is up-regulated in activated goldfish macrophages |
| Q81498808 | Age-related differences in sensitivity of peripheral blood monocytes to lipopolysaccharide and Staphylococcus aureus toxin B in atopic dermatitis |
| Q37584038 | Analysis of the toll-like receptor 2-2 (TLR2-2) and TLR4 mRNA expression in the intestinal mucosal immunity of broilers fed on diets supplemented with nickel chloride |
| Q57201037 | Antagonism between MyD88- and TRIF-dependent signals in B7RP-1 up-regulation |
| Q42216402 | Anti-Toll-like receptor 2 and 4 antibodies suppress inflammatory response in mice. |
| Q37460476 | Antigen receptor signals rescue B cells from TLR tolerance. |
| Q33583872 | Augmented osteogenic responses in human aortic valve cells exposed to oxLDL and TLR4 agonist: a mechanistic role of Notch1 and NF-κB interaction |
| Q39549554 | Bacterial lipoprotein-induced tolerance is reversed by overexpression of IRAK-1. |
| Q41434606 | Blueprints of signaling interactions between pattern recognition receptors: implications for the design of vaccine adjuvants. |
| Q42370494 | Bone Morphogenetic Protein 9 Enhances Lipopolysaccharide-Induced Leukocyte Recruitment to the Vascular Endothelium |
| Q35106547 | Borrelia burgdorferi-induced tolerance as a model of persistence via immunosuppression |
| Q40263359 | Cellular Decision Making by Non-Integrative Processing of TLR Inputs. |
| Q41898694 | Chlorella sorokiniana-Induced Activation and Maturation of Human Monocyte-Derived Dendritic Cells through NF-κB and PI3K/MAPK Pathways |
| Q36100130 | Chronic TLR Stimulation Controls NLRP3 Inflammasome Activation through IL-10 Mediated Regulation of NLRP3 Expression and Caspase-8 Activation |
| Q35675933 | Comparison of sublingual therapeutic vaccine with antibiotics for the prophylaxis of recurrent urinary tract infections |
| Q36743540 | Cooperation of Toll-like receptor signals in innate immune defence |
| Q39672143 | Counteracting interactions between lipopolysaccharide molecules with differential activation of toll-like receptors |
| Q79920608 | Crohn's disease patients homozygous for the 3020insC NOD2 mutation have a defective NOD2/TLR4 cross-tolerance to intestinal stimuli |
| Q35439783 | Crucial and diverse role of the interleukin-33/ST2 axis in infectious diseases |
| Q42598718 | Cumulative Toll-Like Receptor Activation in Human Macrophages Treated with Whole Bacteria |
| Q38321074 | Differential effects of CpG-DNA in Toll-like receptor-2/-4/-9 tolerance and cross-tolerance |
| Q35546440 | Differential effects of Gram-positive versus Gram-negative bacteria on NOSII and TNFalpha in macrophages: role of TLRs in synergy between the two |
| Q80136116 | Endotoxin modulates the capacity of CpG-activated liver myeloid DC to direct Th1-type responses |
| Q37456225 | Engagement of CD44 by hyaluronan suppresses TLR4 signaling and the septic response to LPS. |
| Q50335551 | Essential function for the kinase TAK1 in innate and adaptive immune responses |
| Q36508455 | Evaluation of a therapeutic vaccine for the prevention of recurrent urinary tract infections versus prophylactic treatment with antibiotics |
| Q55426099 | Exacerbation of hepatic injury during rodent malaria by myeloid-related protein 14. |
| Q33987810 | Exposure to HIV-1-encoded Toll-like receptor 8 ligands enhances monocyte response to microbial encoded Toll-like receptor 2/4 ligands |
| Q36479398 | Expression of TOLL-like receptors (TLR) by bovine antigen-presenting cells-potential role in pathogen discrimination? |
| Q24319761 | Expression of functional Toll-like receptor 2 on human epidermal keratinocytes |
| Q53670754 | Expression of tumour necrosis factor receptor and Toll-like receptor 2 and 4 on peripheral blood leucocytes of human volunteers after endotoxin challenge: a comparison of flow cytometric light scatter and immunofluorescence gating. |
| Q89574388 | Extracellular CIRP induces macrophage endotoxin tolerance through IL-6R-mediated STAT3 activation |
| Q40197634 | Genetic analysis of the innate immune responses in wild-derived inbred strains of mice |
| Q36409242 | Gram-positive and Gram-negative bacteria synergize with oxidants to release CXCL8 from innate immune cells |
| Q58562247 | How toll-like receptors reveal monocyte plasticity: the cutting edge of antiinflammatory therapy |
| Q34333969 | IL-10-dependent partial refractoriness to Toll-like receptor stimulation modulates gut mucosal dendritic cell function. |
| Q51744041 | IL-33 Treatment Attenuates the Systemic Inflammation Reaction in Acinetobacter baumannii Pneumonia by Suppressing TLR4/NF-κB Signaling. |
| Q53521059 | Identification of a novel negative role of flagellin in regulating IL-10 production. |
| Q37232946 | Immune dysregulation in severe influenza |
| Q42975888 | Immune reconstitution inflammatory syndrome in association with HIV/AIDS and tuberculosis: views over hidden possibilities |
| Q39001670 | Immunological priming requires regulatory T cells and IL-10-producing macrophages to accelerate resolution from severe lung inflammation |
| Q39753707 | Induction of endotoxin tolerance in vivo inhibits activation of IRAK4 and increases negative regulators IRAK-M, SHIP-1, and A20. |
| Q40754849 | Inflammatory cytokine response to Bacillus anthracis peptidoglycan requires phagocytosis and lysosomal trafficking |
| Q28611075 | Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4 |
| Q42410751 | Innate immune regulation by toll-like receptors in the brain |
| Q35050603 | Innate immune responses to microbial poisons: discovery and function of the Toll-like receptors |
| Q37801037 | Innate immunity and cancer therapy |
| Q77999992 | Involvement of ERK, p38 and NF-kappaB signal transduction in regulation of TLR2, TLR4 and TLR9 gene expression induced by lipopolysaccharide in mouse dendritic cells |
| Q40633161 | Involvement of Leucine Residues at Positions 107, 112, and 115 in a Leucine-Rich Repeat Motif of Human Toll-Like Receptor 2 in the Recognition of Diacylated Lipoproteins and Lipopeptides and Staphylococcus aureus Peptidoglycans |
| Q34281709 | Involvement of TLR2 and TLR4 in cell responses to Rickettsia akari |
| Q35363337 | Junin virus infects mouse cells and induces innate immune responses. |
| Q38496963 | Lipid A-Mediated Tolerance and Cancer Therapy |
| Q39656127 | Lipopolysaccharide desensitization of macrophages provides protection against Yersinia enterocolitica-induced apoptosis |
| Q37417268 | Lipopolysaccharide directly alters renal tubule transport through distinct TLR4-dependent pathways in basolateral and apical membranes |
| Q35737838 | Lipopolysaccharide-induced human enterocyte tolerance to cytokine-mediated interleukin-8 production may occur independently of TLR-4/MD-2 signaling |
| Q33910726 | Lipoprotein-dependent and -independent immune responses to spirochetal infection |
| Q39887518 | Lipoteichoic acid and peptidoglycan from Staphylococcus aureus synergistically induce neutrophil influx into the lungs of mice |
| Q35061594 | Lysophosphatidylcholine triggers TLR2- and TLR4-mediated signaling pathways but counteracts LPS-induced NO synthesis in peritoneal macrophages by inhibiting NF-κB translocation and MAPK/ERK phosphorylation |
| Q34837522 | Macrophage subset sensitivity to endotoxin tolerisation by Porphyromonas gingivalis |
| Q64962353 | Macrophage subsets exhibit distinct E. coli-LPS tolerisable cytokines associated with the negative regulators, IRAK-M and Tollip. |
| Q24291852 | Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state |
| Q28750086 | Maggot secretions skew monocyte-macrophage differentiation away from a pro-inflammatory to a pro-angiogenic type |
| Q36717761 | Mechanistic role of microRNA-146a in endotoxin-induced differential cross-regulation of TLR signaling |
| Q36745742 | MicroRNA in TLR signaling and endotoxin tolerance. |
| Q24299367 | Modulation of TLR4 signaling by a novel adaptor protein signal-transducing adaptor protein-2 in macrophages |
| Q37079814 | Molecular and cellular aspects of sepsis-induced immunosuppression |
| Q35580690 | Molecular mechanisms of macrophage activation and deactivation by lipopolysaccharide: roles of the receptor complex |
| Q88612161 | Monophosphoryl lipid A prevents impairment of medullary thick ascending limb [Formula: see text] absorption and improves plasma [Formula: see text] concentration in septic mice |
| Q91701808 | Mucosal bacterial immunotherapy with MV130 highly reduces the need of tonsillectomy in adults with recurrent tonsillitis |
| Q40214360 | Murine osteoblasts respond to LPS and IFN-gamma similarly to macrophages |
| Q36447529 | Naturally Occurring Subclinical Endotoxemia in Humans Alters Adaptive and Innate Immune Functions through Reduced MAPK and Increased STAT1 Phosphorylation |
| Q36231107 | Negative regulation of cytokine and TLR signalings by SOCS and others |
| Q39632490 | Nucleic acids of Enterococcus faecalis strain EC-12 are potent Toll-like receptor 7 and 9 ligands inducing interleukin-12 production from murine splenocytes and murine macrophage cell line J774.1 |
| Q55071955 | Outer membrane vesicles blebbing contributes to B. vulgatus mpk-mediated immune response silencing. |
| Q85046669 | Pathogen associated molecular pattern motifs from Gram-positive and Gram-negative bacteria induce different inflammatory mediator profiles in equine blood |
| Q39491064 | Porphyromonas gingivalis Outer Membrane Vesicles Induce Selective Tumor Necrosis Factor Tolerance in a Toll-Like Receptor 4- and mTOR-Dependent Manner |
| Q37016121 | Pretreatment with the Gram-positive bacterial cell wall molecule peptidoglycan improves bacterial clearance and decreases inflammation and mortality in mice challenged with Pseudomonas aeruginosa |
| Q37029199 | Pretreatment with the Gram-positive bacterial cell wall molecule peptidoglycan improves bacterial clearance and decreases inflammation and mortality in mice challenged with Staphylococcus aureus |
| Q64082904 | Probiotic Lactobacillus rhamnosus GR-1 is a unique prophylactic agent that suppresses infection-induced myometrial cell responses |
| Q36018223 | Pseudomonas aeruginosa elastase cleaves a C-terminal peptide from human thrombin that inhibits host inflammatory responses |
| Q93204275 | Recent clinical trends in Toll-like receptor targeting therapeutics |
| Q34559002 | Regulation of Toll-like receptor (TLR)2 and TLR4 on CD14dimCD16+ monocytes in response to sepsis-related antigens |
| Q36919994 | Role of macrophage receptor with collagenous structure in innate immune tolerance |
| Q34426677 | Role of toll like receptors in irritable bowel syndrome: differential mucosal immune activation according to the disease subtype |
| Q40504254 | Secreted tryptophanyl-tRNA synthetase as a primary defence system against infection |
| Q37139993 | Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells |
| Q38681728 | Self-regulation and cross-regulation of pattern-recognition receptor signalling in health and disease |
| Q35575529 | Shielding the double-edged sword: negative regulation of the innate immune system |
| Q34731395 | Single nucleotide polymorphisms in pathogen recognition receptor genes are associated with susceptibility to meningococcal meningitis in a pediatric cohort. |
| Q34120333 | Site-specific proteolysis of the MALP-404 lipoprotein determines the release of a soluble selective lipoprotein-associated motif-containing fragment and alteration of the surface phenotype of Mycoplasma fermentans |
| Q36357954 | Structural diversity of Burkholderia pseudomallei lipopolysaccharides affects innate immune signaling |
| Q27008875 | TLR cross-talk confers specificity to innate immunity |
| Q33775405 | TLR cross-talk specifically regulates cytokine production by B cells from chronic inflammatory disease patients |
| Q41562731 | TLR2 and TLR9 modulate enteric nervous system inflammatory responses to lipopolysaccharide. |
| Q37214782 | TLR2 synergizes with both TLR4 and TLR9 for induction of the MyD88-dependent splenic cytokine and chemokine response to Streptococcus pneumoniae |
| Q33771736 | TLR3-mediated NF-{kappa}B signaling in human esophageal epithelial cells |
| Q40744508 | TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages. |
| Q27010345 | Targeting toll-like receptors: promising therapeutic strategies for the management of sepsis-associated pathology and infectious diseases |
| Q82385519 | The effect of azithromycin on the maturation and function of murine bone marrow-derived dendritic cells |
| Q51740589 | The effects of repeated Toll-like receptors 2 and 4 stimulation in COPD alveolar macrophages. |
| Q54627218 | The immunomodulator ginsan induces resistance to experimental sepsis by inhibiting Toll-like receptor-mediated inflammatory signals. |
| Q27022093 | The immunopathology of sepsis: pathogen recognition, systemic inflammation, the compensatory anti-inflammatory response, and regulatory T cells |
| Q42925255 | The impact of single and pairwise Toll-like receptor activation on neuroinflammation and neurodegeneration |
| Q37214491 | The multiple facets of toll-like receptors in transplantation biology |
| Q36844715 | The perfect mix: recent progress in adjuvant research |
| Q37726702 | The role of epithelial integrin receptors in recognition of pulmonary pathogens |
| Q90442981 | Tolerance induced by Porphyromonas gingivalis may occur independently of TLR2 and TLR4 |
| Q34727357 | Toll receptors, CD14, and macrophage activation and deactivation by LPS. |
| Q40649503 | Toll-Like Receptor 2 (TLR2) and TLR9 Signaling Results in HIV-Long Terminal RepeatTrans-Activation and HIV Replication in HIV-1 Transgenic Mouse Spleen Cells: Implications of Simultaneous Activation of TLRs on HIV Replication |
| Q46895698 | Toll-Like Receptor Ligand-Induced Liver Injury in D-Galactosamine-Sensitized Mice: Differences between TLR7/8 and TLR9 Ligands, Cytokine Patterns, and Cross-Tolerance Induction by TLR2 Ligand Pretreatment. |
| Q47961731 | Toll-like receptor 2 and nucleotide-binding oligomerization domain-2 play divergent roles in the recognition of gut-derived lactobacilli and bifidobacteria in dendritic cells |
| Q24814235 | Toll-like receptor 2 expression is decreased on alveolar macrophages in cigarette smokers and COPD patients |
| Q35164987 | Toll-like receptor 2- and 6-mediated stimulation by macrophage-activating lipopeptide 2 induces lipopolysaccharide (LPS) cross tolerance in mice, which results in protection from tumor necrosis factor alpha but in only partial protection from lethal |
| Q33946805 | Toll-like receptor 4 mediates tolerance in macrophages stimulated with Toxoplasma gondii-derived heat shock protein 70. |
| Q34566966 | Toll-like receptor 9: a new target of ischemic preconditioning in the brain |
| Q79223858 | Toll-like receptor interactions: tolerance of MyD88-dependent cytokines but enhancement of MyD88-independent interferon-beta production |
| Q37088298 | Toll-like receptor signaling: a critical modulator of cell survival and ischemic injury in the heart |
| Q34552745 | Toll-like receptors TLR2 and TLR4 initiate the innate immune response of the renal tubular epithelium to bacterial products. |
| Q34296477 | Toll-like receptors and innate immunity. |
| Q37265030 | Toll-like receptors in skin infections and inflammatory diseases. |
| Q37490474 | Toxoplasma gondii-derived heat shock protein HSP70 functions as a B cell mitogen |
| Q37696067 | Transcriptional control of the TNF gene |
| Q30478122 | Transcriptional noise and cellular heterogeneity in mammalian macrophages |
| Q37372289 | Wolbachia lipoprotein stimulates innate and adaptive immunity through Toll-like receptors 2 and 6 to induce disease manifestations of filariasis. |
| Q52626404 | [The role of innate immunity in otitis media]. |
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