LOX-1 mediates lysophosphatidylcholine-induced oxidized LDL uptake in smooth muscle cells

scientific article published on 01 February 2000

LOX-1 mediates lysophosphatidylcholine-induced oxidized LDL uptake in smooth muscle cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0014-5793(00)01154-6
P698PubMed publication ID10675541

P2093author name stringM Chen
T Masaki
T Sawamura
H Fujiwara
T Aoyama
P2860cites workOxidized LDL regulates macrophage gene expression through ligand activation of PPARgammaQ24311702
An endothelial receptor for oxidized low-density lipoproteinQ24323462
Identification of the lectin-like receptor for oxidized low-density lipoprotein in human macrophages and its potential role as a scavenger receptorQ24531178
Expression of lectinlike oxidized low-density lipoprotein receptor-1 in human atherosclerotic lesionsQ28137864
Upregulation of endothelial receptor for oxidized low-density lipoprotein (LOX-1) in cultured human coronary artery endothelial cells by angiotensin II type 1 receptor activationQ28143907
Identification and autoregulation of receptor for OX-LDL in cultured human coronary artery endothelial cellsQ28279585
Genomic organization and regulation of expression of the lectin-like oxidized low-density lipoprotein receptor (LOX-1) geneQ28290435
The expression of the lectin-like oxidized low-density lipoprotein receptor (LOX-1) on human vascular smooth muscle cells and monocytes and its down-regulation by lovastatinQ28296378
The pathogenesis of atherosclerosis: a perspective for the 1990sQ29547827
Lysophosphatidylcholine transcriptionally induces growth factor gene expression in cultured human endothelial cellsQ34128848
Rabbit aortic smooth muscle cells express inducible macrophage scavenger receptor messenger RNA that is absent from endothelial cellsQ35607034
Lysophosphatidylcholine, a component of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules in cultured human and rabbit arterial endothelial cellsQ35822759
Lectin-like oxidized low-density lipoprotein receptor 1 mediates phagocytosis of aged/apoptotic cells in endothelial cellsQ36265106
Expression of lectin-like oxidized low density lipoprotein receptor-1 in human and murine macrophages: upregulated expression by TNF-alphaQ40986652
Altered expression of alpha-actin, smooth muscle myosin heavy chain-1 and calponin in cultured smooth muscle cells by oxidized low density lipoproteinsQ41051581
High-affinity arginine transport of bovine aortic endothelial cells is impaired by lysophosphatidylcholine.Q50521487
Impairment of endothelium-dependent arterial relaxation by lysolecithin in modified low-density lipoproteinsQ59060592
Oxidized low-density lipoprotein is chemotactic for arterial smooth muscle cells in cultureQ68646151
Active oxygen species and lysophosphatidylcholine are involved in oxidized low density lipoprotein activation of smooth muscle cell DNA synthesisQ71055872
Oxidized low density lipoprotein and lysophosphatidylcholine stimulate cell cycle entry in vascular smooth muscle cells. Evidence for release of fibroblast growth factor-2Q71143962
Oxidized low density lipoprotein stimulates collagen production in cultured arterial smooth muscle cellsQ71561362
Enhanced expression of endothelial oxidized low-density lipoprotein receptor (LOX-1) in hypertensive ratsQ73702881
Oxidized low density lipoprotein induces apoptosis in cultured human umbilical vein endothelial cells by common and unique mechanismsQ74450479
Inducible expression of lectin-like oxidized LDL receptor-1 in vascular endothelial cellsQ77114847
Depending on their concentration oxidized low density lipoproteins stimulate extracellular matrix synthesis or induce apoptosis in human coronary artery smooth muscle cellsQ77827275
Angiotensin II induces LOX-1, the human endothelial receptor for oxidized low-density lipoproteinQ78195714
P433issue2-3
P304page(s)217-220
P577publication date2000-02-01
P1433published inFEBS LettersQ1388051
P1476titleLOX-1 mediates lysophosphatidylcholine-induced oxidized LDL uptake in smooth muscle cells
P478volume467

Reverse relations

cites work (P2860)
Q38724228Atherogenesis: hyperhomocysteinemia interactions with LDL, macrophage function, paraoxonase 1, and exercise
Q50351148C-Type Lectin-Like Receptors As Emerging Orchestrators of Sterile Inflammation Represent Potential Therapeutic Targets.
Q90055176C-Type Lectin-Like Receptors: Head or Tail in Cell Death Immunity
Q28533974Celastrol prevents atherosclerosis via inhibiting LOX-1 and oxidative stress
Q24532675Conserved C-terminal residues within the lectin-like domain of LOX-1 are essential for oxidized low-density-lipoprotein binding
Q46278173Contribution of lectin-like oxidized low-density lipoprotein receptor-1 and LOX-1 modulating compounds to vascular diseases
Q36022217Deletion of LOX-1 Protects against Heart Failure Induced by Doxorubicin
Q37639902Endothelium and its alterations in cardiovascular diseases: life style intervention
Q36744066Expression and localization of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in murine and human placentas
Q50059271Increased Levels of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Ischemic Stroke and Transient Ischemic Attack
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Q37690728LOX-1 and Its Splice Variants: A New Challenge for Atherosclerosis and Cancer-Targeted Therapies
Q37297831LOX-1 augments oxLDL uptake by lysoPC-stimulated murine macrophages but is not required for oxLDL clearance from plasma
Q28565059LOX-1 expressed in cultured rat chondrocytes mediates oxidized LDL-induced cell death-possible role of dephosphorylation of Akt
Q34712581LOX-1 plays an important role in ischemia-induced angiogenesis of limbs
Q40376526LOX-1 scavenger receptor mediates calcium-dependent recognition of phosphatidylserine and apoptotic cells
Q38128283LOX-1, OxLDL, and atherosclerosis
Q34774368LOX-1, the receptor for oxidized low-density lipoprotein identified from endothelial cells: implications in endothelial dysfunction and atherosclerosis
Q38829882LOX-1-Mediated Effects on Vascular Cells in Atherosclerosis
Q38155327LOX-1: a male hormone-regulated scavenger receptor for atherosclerosis
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Q38299554Requirements of basic amino acid residues within the lectin-like domain of LOX-1 for the binding of oxidized low-density lipoprotein
Q39335213Tanshinone II-A inhibits oxidized LDL-induced LOX-1 expression in macrophages by reducing intracellular superoxide radical generation and NF-κB activation.
Q35475499The discovery of LOX-1, its ligands and clinical significance
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