Extrahepatic first-pass metabolism of nifedipine in the rat

scientific article published on 01 August 1997

Extrahepatic first-pass metabolism of nifedipine in the rat is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/(SICI)1099-081X(199708)18:6<509::AID-BDD38>3.0.CO;2-5
P698PubMed publication ID9267683

P2093author name stringJ S Grundy
R T Foster
L A Eliot
P433issue6
P921main subjectnifedipineQ39111
P304page(s)509-522
P577publication date1997-08-01
P1433published inBiopharmaceutics and Drug DispositionQ15766879
P1476titleExtrahepatic first-pass metabolism of nifedipine in the rat
P478volume18

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cites work (P2860)
Q40359652A physiologically based pharmacokinetic model to predict the pharmacokinetics of highly protein-bound drugs and the impact of errors in plasma protein binding
Q37104008An intestinal epithelium-specific cytochrome P450 (P450) reductase-knockout mouse model: direct evidence for a role of intestinal p450s in first-pass clearance of oral nifedipine
Q37534607Contribution of baicalin on the plasma protein binding displacement and CYP3A activity inhibition to the pharmacokinetic changes of nifedipine in rats in vivo and in vitro.
Q84415824Contribution of rat intestinal metabolism to the xenobiotics clearance
Q35045446Despite increased plasma concentration, inflammation reduces potency of calcium channel antagonists due to lower binding to the rat heart
Q74663308Effects of hyperlipidemia on the pharmacokinetics of nifedipine in the rat
Q41828997Pharmacokinetics of dietary cancer chemopreventive compound dibenzoylmethane in rats and the impact of nanoemulsion and genetic knockout of Nrf2 on its disposition

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