Relationship between interferon-gamma, interleukin-10, and interleukin-12 production in chronic hepatitis C and in vitro effects of interferon-alpha

scientific article published on 01 January 2000

Relationship between interferon-gamma, interleukin-10, and interleukin-12 production in chronic hepatitis C and in vitro effects of interferon-alpha is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1019661980
P356DOI10.1023/A:1006694627907
P698PubMed publication ID10798608

P2093author name stringO Schiraldi
C Tortorella
S Antonaci
G Piazzolla
P2860cites workCostimulatory molecules and cytotoxic T cells in chronic hepatitis C: defence mechanisms devoted to host integrity or harmful events favouring liver injury progression? A reviewQ77522128
Enhanced induction of interleukin-12(p40) secretion by human macrophages infected with Mycobacterium avium complex isolates from disseminated infection in AIDS patientsQ77524616
Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cellsQ24295111
Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activityQ24306484
Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cellsQ24338274
Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 gQ26778365
HLA class I-restricted cytotoxic T lymphocytes specific for hepatitis C virus. Identification of multiple epitopes and characterization of patterns of cytokine releaseQ27478341
Production of interleukins 10 and 12 by peripheral blood mononuclear cells (PBMC) in chronic hepatitis C virus (HCV) infectionQ27480408
Functional diversity of helper T lymphocytesQ29619415
Interferon-alpha/beta inhibition of interleukin 12 and interferon-gamma production in vitro and endogenously during viral infectionQ35958851
Regulation of immunity to parasites by T cells and T cell-derived cytokinesQ36135203
Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytesQ36356764
Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cellsQ36362214
Interleukin 4 suppresses interleukin 2 and interferon gamma production by naive T cells stimulated by accessory cell-dependent receptor engagementQ36383339
Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such primingQ36638672
Cytotoxic T cells and viral hepatitisQ37365416
Heterogeneity of cytokine secretion patterns and functions of helper T cellsQ38257524
Interferon-gamma, the activated macrophage, and host defense against microbial challengeQ39601454
Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytesQ40651348
Lymphokine production by human T cells in disease statesQ40661109
A TH1-->TH2 switch is a critical step in the etiology of HIV infectionQ40709038
Human Th1 and Th2 cells: functional properties, mechanisms of regulation, and role in diseaseQ40734508
The expanding universe of T-cell subsets: Th1, Th2 and more.Q41120396
IFN-gamma-inducing factor (IGIF) is a costimulatory factor on the activation of Th1 but not Th2 cells and exerts its effect independently of IL-12.Q41127638
Interleukin-12: potential clinical applications in the treatment and prevention of infectious diseases.Q41164186
Studies of interleukin-12 in chronic hepatitis B virus infectionQ41681599
Immunoregulatory cytokines in chronic hepatitis C virus infection: pre- and posttreatment with interferon alfaQ42977701
Chronic hepatitis C: T-helper1/T-helper2 imbalance could cause virus persistence in peripheral bloodQ42986510
Interrelationship of blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma: analysis by detection of antibody to hepatitis C virusQ42987918
Immune response to a hepatitis C virus nonstructural protein in chronic hepatitis C virus infection.Q43036567
Interferon gamma production by peripheral blood lymphocytes to hepatitis C virus core protein in chronic hepatitis C infectionQ43037383
Defining protective responses to pathogens: cytokine profiles in leprosy lesionsQ43702135
Detection of type 2-like T-helper cells in hepatitis C virus infection: implications for hepatitis C virus chronicityQ45764886
Evaluation of cellular immune responses and soluble mediators in patients with chronic hepatitis C virus (cHCV) infectionQ45787483
In vivo production and function of IL-12 p40 homodimers.Q50134634
Heterogeneity of mouse helper T cells. Evidence from bulk cultures and limiting dilution cloning for precursors of Th1 and Th2 cells.Q51169514
Transforming growth factor-beta inhibits interleukin-12-induced production of interferon-gamma by natural killer cells: a role for transforming growth factor-beta in the regulation of T cell-independent resistance to Toxoplasma gondii.Q54176145
Cytochemical Identification of Monocytes and GranulocytesQ71772139
Phenotypical analysis and cytokine release of liver-infiltrating and peripheral blood T lymphocytes from patients with chronic hepatitis of different etiologyQ72168698
Serum soluble CD23 but not IL8, IL10, GM-CSF, or IFN-gamma is elevated in patients with hepatitis C infectionQ73561521
Type I IFNs inhibit human dendritic cell IL-12 production and Th1 cell developmentQ74515353
IFN-alpha priming of human monocytes differentially regulates gram-positive and gram-negative bacteria-induced IL-10 release and selectively enhances IL-12p70, CD80, and MHC class I expressionQ77123518
Plasma transforming growth factor-beta 1 concentrations in patients with chronic viral hepatitisQ77139857
P433issue1
P921main subjecthepatitis CQ154869
chronic hepatitis CQ55779873
chronic hepatitisQ62019625
P304page(s)54-61
P577publication date2000-01-01
P1433published inJournal of Clinical ImmunologyQ6294961
P1476titleRelationship between interferon-gamma, interleukin-10, and interleukin-12 production in chronic hepatitis C and in vitro effects of interferon-alpha
P478volume20

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cites work (P2860)
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Q58803426IL-10 and TNF-α polymorphisms and the recovery from HCV infection
Q42991769Immunogenic properties of a chimeric plant virus expressing a hepatitis C virus (HCV)-derived epitope: new prospects for an HCV vaccine
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Q36206644Restoration of innate and adaptive immune responses by HCV viral inhibition with an induction approach using natural interferon-beta in chronic hepatitis C

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