Human influenza A viruses are proteolytically activated and do not induce apoptosis in CACO-2 cells

scientific article published on 01 August 2003

Human influenza A viruses are proteolytically activated and do not induce apoptosis in CACO-2 cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0042-6822(03)00264-2
P698PubMed publication ID12951033

P2093author name stringHans-Dieter Klenk
Oleg Zhirnov
P2860cites workStructure of the hemagglutinin precursor cleavage site, a determinant of influenza pathogenicity and the origin of the labile conformationQ27766025
Characterization of influenza virus-induced death of J774.1 macrophagesQ28246408
Induction of a Common Pathway of Apoptosis by StaurosporineQ29042381
Interactions between bacteria and influenza A virus in the development of influenza pneumoniaQ29393081
Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: evidence for membrane cycling from Golgi to ERQ29615171
Role of hemagglutinin cleavage for the pathogenicity of influenza virus.Q30322358
A novel mechanism for the acquisition of virulence by a human influenza A virusQ30431264
Alpha/beta interferons potentiate virus-induced apoptosis through activation of the FADD/Caspase-8 death signaling pathwayQ33793783
Sindbis virus-induced neuronal death is both necrotic and apoptotic and is ameliorated by N-methyl-D-aspartate receptor antagonistsQ33844576
Characterization of a porcine lung epithelial cell line suitable for influenza virus studiesQ33846086
Influenza virus ns1 protein induces apoptosis in cultured cellsQ33853489
Immunocytochemical detection and mapping of a cytokeratin 18 neo-epitope exposed during early apoptosisQ33867352
Intestinal influenza: Replication and characterization of influenza viruses in ducksQ34340529
Studies on the primary structure of the influenza virus hemagglutininQ35066138
Cleavage of influenza A virus H1 hemagglutinin by swine respiratory bacterial proteasesQ35895619
Necrotic death pathway in Fas receptor signalingQ36360371
Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and AblQ36365371
The involvement of a stress-activated pathway in equine influenza virus-mediated apoptosisQ38297815
Caspase-dependent N-terminal cleavage of influenza virus nucleocapsid protein in infected cells.Q39597061
NS1 protein of influenza A virus down-regulates apoptosisQ39682460
Cleavage of influenza a virus hemagglutinin in human respiratory epithelium is cell associated and sensitive to exogenous antiproteasesQ39684429
Release of macrophage migration inhibitory factor and CXCL8/interleukin-8 from lung epithelial cells rendered necrotic by influenza A virus infectionQ39684491
Enhancement of the infectivity of influenza A and B viruses by proteolytic cleavage of the hemagglutinin polypeptideQ39752742
Activation of influenza A viruses by trypsin treatmentQ39965584
Human influenza virus hemagglutinin with high sensitivity to proteolytic activation.Q40066907
Human plasma proteinase inhibitorsQ40107740
The end of the (cell) line: methods for the study of apoptosis in vitro.Q40402381
Host cell proteases controlling virus pathogenicityQ40742881
Murine polyomavirus infection of 3T6 mouse cells shows evidence of predominant necrosis as well as limited apoptosisQ40885336
Common regulation of apoptosis signaling induced by CD95 and the DNA-damaging stimuli etoposide and gamma-radiation downstream from caspase-8 activationQ40955328
Role of neuraminidase in influenza virus-induced apoptosisQ40975050
Death mechanisms in cultured cells infected by Semliki Forest virusQ41102203
Inhibition of proteolytic activation of influenza virus hemagglutinin by specific peptidyl chloroalkyl ketonesQ41513600
Induction of programmed cell death (apoptosis) by influenza virus infection in tissue culture cellsQ41519616
Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formationQ41570746
Location and character of the cellular enzyme that cleaves the hemagglutinin of a virulent avian influenza virusQ41603918
High protection of animals lethally infected with influenza virus by aprotinin-rimantadine combinationQ43485375
Mini-plasmin found in the epithelial cells of bronchioles triggers infection by broad-spectrum influenza A viruses and Sendai virusQ43612047
Proteolytic cleavage by plasmin of the HA polypeptide of influenza virus: host cell activation of serum plasminogenQ43792248
Proteolytic activation of the influenza virus hemagglutinin: The structure of the cleavage site and the enzymes involved in cleavageQ44290452
Is virulence of H5N2 influenza viruses in chickens associated with loss of carbohydrate from the hemagglutinin?Q44730162
Synergistic role of staphylococcal proteases in the induction of influenza virus pathogenicityQ45130421
Pulmonary surfactant is a potential endogenous inhibitor of proteolytic activation of Sendai virus and influenza A virusQ45775373
Cell tropism of influenza virus mediated by hemagglutinin activation at the stage of virus entryQ45780778
Activation of an influenza virus A/turkey/Oregon/71 HA insertion variant by the subtilisin-like endoprotease furinQ45781261
Proteolytic Activation of Influenza WSN Virus in Cultured Cells is Performed by Homologous Plasma EnzymesQ45804114
Suppression of Influenza Virus Replication in Infected Mice by Protease InhibitorsQ45804533
Role of respiratory tract proteases in infectivity of influenza A virusQ45830837
Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis.Q51091938
Membrane fusionQ67584890
Caco-2 cells cultured in serum-free medium as a model for the study of enterocytic differentiation in vitroQ68041338
Myxovirus replication in chicken embryos can be suppressed by aprotinin due to the blockage of viral glycoprotein cleavageQ68937975
Intestinal replication of influenza A viruses in two mammalian species. Brief reportQ69778314
A modified plaque assay method for accurate analysis of infectivity of influenza viruses with uncleaved hemagglutininQ70304294
Aprotinin aerosol treatment of influenza and paramyxovirus bronchopneumonia of miceQ71616889
Physical characterization of ovoinhibitor, a trypsin and chymotrypsin inhibitor from chicken egg whiteQ72923941
Human mucus protease inhibitor in airway fluids is a potential defensive compound against infection with influenza A and Sendai virusesQ73194504
Inhibition of caspase activity induces a switch from apoptosis to necrosisQ74480871
A mono phenylalanine-based motif (F790) and a leucine-dependent motif (LI760) mediate internalization of furinQ77372649
Two types of death of poliovirus-infected cells: caspase involvement in the apoptosis but not cytopathic effectQ77760845
P433issue1
P921main subjectapoptotic processQ14599311
proteolysisQ33123
Caco-2Q5016050
P304page(s)198-212
P577publication date2003-08-01
P1476titleHuman influenza A viruses are proteolytically activated and do not induce apoptosis in CACO-2 cells
P478volume313

Reverse relations

cites work (P2860)
Q33516234Cleavage of the SARS coronavirus spike glycoprotein by airway proteases enhances virus entry into human bronchial epithelial cells in vitro
Q30425455Comparison of different cell substrates on the measurement of human influenza virus neutralizing antibodies
Q33707307Consequences of immunodominant epitope deletion for minor influenza virus-specific CD8+-T-cell responses
Q30396047Development and strategies of cell-culture technology for influenza vaccine
Q33831147Exploring the effect of biological delays in kinetic models of influenza within a host or cell culture
Q30414319Health costs from hospitalization with H1N1 infection during the 2009-2010 influenza pandemic compared with non-H1N1 respiratory infections
Q35171172Influenza A virus encoding secreted Gaussia luciferase as useful tool to analyze viral replication and its inhibition by antiviral compounds and cellular proteins
Q35565733Influenza A virus infection of intestinal epithelial cells enhances the adhesion ability of Crohn's disease associated Escherichia coli strains
Q30404200Long-term respiratory follow-up of H1N1 infection
Q27027915Macrolide therapy in respiratory viral infections
Q37959271Macrolides: from in vitro anti-inflammatory and immunomodulatory properties to clinical practice in respiratory diseases.
Q39972881Maturation efficiency of viral glycoproteins in the ER impacts the production of influenza A virus
Q37772440Novel insights into proteolytic cleavage of influenza virus hemagglutinin
Q34059067Oncolytic activity of avian influenza virus in human pancreatic ductal adenocarcinoma cell lines
Q28483092Oncolytic effects of a novel influenza A virus expressing interleukin-15 from the NS reading frame
Q28083816Prevalence of gastrointestinal symptoms in patients with influenza, clinical significance, and pathophysiology of human influenza viruses in faecal samples: what do we know?
Q42483821Serum-dependent expression of promyelocytic leukemia protein suppresses propagation of influenza virus
Q34674604Sulfatide regulates caspase-3-independent apoptosis of influenza A virus through viral PB1-F2 protein
Q34120814TMPRSS2 and TMPRSS4 facilitate trypsin-independent spread of influenza virus in Caco-2 cells.
Q37252750TMPRSS2 is an activating protease for respiratory parainfluenza viruses.
Q30395821The 2009 Pandemic H1N1 and Triple-Reassortant Swine H1N1 Influenza Viruses Replicate Efficiently but Elicit an Attenuated Inflammatory Response in Polarized Human Bronchial Epithelial Cells
Q92527298The inducible amphisome isolates viral hemagglutinin and defends against influenza A virus infection
Q39178737Use of the human colorectal adenocarcinoma (Caco-2) cell line for isolating respiratory viruses from nasopharyngeal aspirates.

Search more.