The effects of dexamethasone and chlorpromazine on tumour necrosis factor-alpha, interleukin-1 beta, interleukin-1 receptor antagonist and interleukin-10 in human volunteers

scientific article published on 01 August 1997

The effects of dexamethasone and chlorpromazine on tumour necrosis factor-alpha, interleukin-1 beta, interleukin-1 receptor antagonist and interleukin-10 in human volunteers is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1046/J.1365-2567.1997.00285.X
P698PubMed publication ID9378493

P2093author name stringB J Kullberg
M G Netea
J W Van der Meer
J Van der Ven-Jongekrijg
M W Bleeker
P2860cites workPassive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxinQ28306447
Chlorpromazine inhibits tumour necrosis factor synthesis and cytotoxicity in vitroQ28378754
Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemiaQ34173960
Dexamethasone inhibition of interleukin 1 beta production by human monocytes. Posttranscriptional mechanismsQ35585405
Elaboration of interleukin 1-receptor antagonist is not attenuated by glucocorticoids after endotoxemiaQ40721842
Pathogenetic mechanisms of septic shockQ40900222
Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoidsQ41283123
Protective effect of chlorpromazine on endotoxin toxicity and TNF production in glucocorticoid-sensitive and glucocorticoid-resistant models of endotoxic shockQ41837133
Adrenalectomy sensitizes mice to the lethal effects of interleukin 1 and tumor necrosis factorQ41839655
A specific receptor antagonist for interleukin 1 prevents Escherichia coli ‐induced shock in rabbitsQ43740171
Inhibition by chlorpromazine of lymphokine-specific mRNA expression in human thymocytesQ44124013
Measurement of immunoreactive interleukin-1 beta from human mononuclear cells: optimization of recovery, intrasubject consistency, and comparison with interleukin-1 alpha and tumor necrosis factorQ44515935
Chlorpromazine specifically inhibits peripheral and brain TNF production, and up-regulates IL-10 production, in mice.Q48117114
Role of tumour necrosis factor and reactive oxygen intermediates in lipopolysaccharide-induced pulmonary oedema and lethality.Q54661310
Chlorpromazine amplifies macrophage-dependent IL-10 production in vivoQ60342761
Glucocorticoids suppress the production of tumour necrosis factor by lipopolysaccharide-stimulated human monocytesQ68290258
The effects of selected drugs, including chlorpromazine and non-steroidal anti-inflammatory agents, on polyclonal IgG synthesis and interleukin 1 production by human peripheral blood mononuclear cells in vitroQ69742371
Glucocorticoid therapy alters hormonal and cytokine responses to endotoxin in manQ70568911
Inhibition of lipopolysaccharide-induced monocyte interleukin-1 receptor antagonist synthesis by cortisol: involvement of the mineralocorticoid receptorQ70871432
Endurance run increases circulating IL-6 and IL-1ra but downregulates ex vivo TNF-alpha and IL-1 beta productionQ70984018
Influence of hypercortisolemia on soluble tumor necrosis factor receptor II and interleukin-1 receptor antagonist responses to endotoxin in human beings*Q71968192
Pharmacological activities of chlorpromazine involved in the inhibition of tumour necrosis factor production in vivo in miceQ72227813
Pharmacologic inhibitors of tumor necrosis factor production exert differential effects in lethal endotoxemia and in infection with live microorganisms in miceQ72515441
P433issue4
P921main subjectchlorpromazineQ407972
dexamethasoneQ422252
P304page(s)548-552
P577publication date1997-08-01
P1433published inImmunologyQ15754984
P1476titleThe effects of dexamethasone and chlorpromazine on tumour necrosis factor-alpha, interleukin-1 beta, interleukin-1 receptor antagonist and interleukin-10 in human volunteers
P478volume91