Platelet-derived growth factor-AA and -alpha receptor expression suggests an autocrine and/or paracrine loop in osteosarcoma

scientific article published on 01 June 2000

Platelet-derived growth factor-AA and -alpha receptor expression suggests an autocrine and/or paracrine loop in osteosarcoma is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1051490430
P356DOI10.1038/MODPATHOL.3880109
P698PubMed publication ID10874667

P2093author name stringLang S
Chott A
Mosberger I
Sulzbacher I
Träxler M
P2860cites workAngiogenesis in cancer, vascular, rheumatoid and other diseaseQ29547165
Platelet-derived growth factor-AA and -BB (PDGF-AA and -BB) enhance the synthesis of PDGF-AA in bone cell culturesQ38307516
Platelet-derived growth factorQ38350498
Platelet-derived growth factor. Structure, function and implications in normal and malignant cell growthQ40821933
Human osteoblasts synthesize and respond to platelet-derived growth factorQ41152763
Human osteosarcoma (U-2 OS) cells express both insulin-like growth factor-I (IGF-I) receptors and insulin-like growth factor-II/mannose-6-phosphate (IGF-II/M6P) receptors and synthesize IGF-II: autocrine growth stimulation by IGF-II via the IGF-I reQ41463316
Platelet derived growth factor (PDGF) autocrine components in human tumor cell linesQ41745683
Growth factor responsiveness of human articular chondrocytes in aging and developmentQ58913113
Production of Platelet-Derived Growth Factor–like Mitogen by Smooth-Muscle Cells from Human AtheromaQ68352602
The potential role of platelet-derived growth factor as an autocrine or paracrine factor for human bone cellsQ69456007
Distribution of platelet-derived growth factor (PDGF) A chain mRNA, protein, and PDGF-alpha receptor in rapidly forming human boneQ71730904
Expression of transforming growth factor-beta (TGF-beta) receptors, TGF-beta 1 and TGF-beta 2 production and autocrine growth control in osteosarcoma cellsQ72107564
Coexpression of a PDGF-like growth factor and PDGF receptors in a human osteosarcoma cell line: Implications for autocrine receptor activationQ72405313
Cell-retained isoforms of vascular endothelial growth factor (VEGF) are correlated with poor prognosis in osteosarcomaQ73112514
Expression of transforming growth factor-beta (TGF-beta) isoforms in osteosarcomas: TGF-beta3 is related to disease progressionQ73954434
Expression of growth factors, growth inhibiting factors, and their receptors in invasive breast cancer. I: An inventory in search of autocrine and paracrine loopsQ74532039
P433issue6
P304page(s)632-637
P577publication date2000-06-01
P1433published inModern PathologyQ15724578
P1476titlePlatelet-derived growth factor-AA and -alpha receptor expression suggests an autocrine and/or paracrine loop in osteosarcoma
P478volume13

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cites work (P2860)
Q34224640A potential oncogenic activity of platelet-derived growth factor d in prostate cancer progression
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Q35894540Bone Sarcomas in Pediatrics: Progress in Our Understanding of Tumor Biology and Implications for Therapy
Q36360588Characterization of the G-quadruplexes in the duplex nuclease hypersensitive element of the PDGF-A promoter and modulation of PDGF-A promoter activity by TMPyP4
Q38161735Current therapeutic strategies and novel approaches in osteosarcoma
Q34640861Differential effects of intermittent and continuous administration of parathyroid hormone on bone histomorphometry and gene expression
Q34130448Dominant negative PDGF-C inhibits growth of Ewing family tumor cell lines
Q36017154Expression of c-kit in human osteosarcoma and its relevance as a prognostic marker
Q47143697Genetic variants of PDGF signaling pathway genes predict cutaneous melanoma survival
Q39647970Hypertrophic Osteoarthropathy Associated With Metastatic Phyllodes Tumor
Q34705278Imatinib mesylate inhibits cell growth of malignant peripheral nerve sheath tumors in vitro and in vivothrough suppression of PDGFR-β
Q39861042Ligand-dependent platelet-derived growth factor receptor (PDGFR)-alpha activation sensitizes rare lung cancer and sarcoma cells to PDGFR kinase inhibitors
Q36272981Molecularly targeted therapy for pediatric brain tumors
Q58803894PDGF/PDGFR effects in osteosarcoma and the "add-on" strategy
Q39330425PDGFs and PDGFRs in canine osteosarcoma: New targets for innovative therapeutic strategies in comparative oncology
Q41285223Platelet derived growth factor (PDGF) contained in Platelet Rich Plasma (PRP) stimulates migration of osteoblasts by reorganizing actin cytoskeleton.
Q77212668Platelet-Derived Growth Factor-α Receptor Expression Supports the Growth of Conventional Chondrosarcoma and Is Associated With Adverse Outcome
Q37109503Platelet-derived growth factor receptor as a prognostic marker and a therapeutic target for imatinib mesylate therapy in osteosarcoma
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Q35186715Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: osteosarcoma and related tumors
Q39959426VEGF-null cells require PDGFR alpha signaling-mediated stromal fibroblast recruitment for tumorigenesis

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