Loss of heterozygosity on the long arm of human chromosome 7 in sporadic renal cell carcinomas

scientific article published on 01 November 1997

Loss of heterozygosity on the long arm of human chromosome 7 in sporadic renal cell carcinomas is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1041003520
P356DOI10.1038/SJ.ONC.1201448
P698PubMed publication ID9400999

P2093author name stringShridhar V
Smith DI
Miller OJ
Petros J
Kalemkerian GP
Sun QC
P433issue22
P407language of work or nameEnglishQ1860
P921main subjectheterozygosityQ124059385
P304page(s)2727-2733
P577publication date1997-11-01
P1433published inOncogeneQ1568657
P1476titleLoss of heterozygosity on the long arm of human chromosome 7 in sporadic renal cell carcinomas
P478volume15

Reverse relations

cites work (P2860)
Q427963187q31-32 allelic loss is a frequent finding in splenic marginal zone lymphoma
Q35791457Absence of caveolin-1 sensitizes mouse skin to carcinogen-induced epidermal hyperplasia and tumor formation
Q34134938Allelic loss and reduced expression of the ING3, a candidate tumor suppressor gene at 7q31, in human head and neck cancers
Q47978602Analysis of the CAVEOLIN-1 gene at human chromosome 7q31.1 in primary tumours and tumour-derived cell lines
Q34104057Anti-tumor activity of fenretinide complexed with human serum albumin in lung cancer xenograft mouse model
Q34515728Are common fragile sites merely structural domains or highly organized "functional" units susceptible to oncogenic stress?
Q35070726Caveolin-1 deficiency (-/-) conveys premalignant alterations in mammary epithelia, with abnormal lumen formation, growth factor independence, and cell invasiveness
Q56101210Caveolin-1 expression in human breast lobular cancer progression
Q28363368Caveolin-1 is down-regulated in human ovarian carcinoma and acts as a candidate tumor suppressor gene
Q35789293Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia
Q33244639Caveolin-1 mutations in human breast cancer: functional association with estrogen receptor alpha-positive status
Q43678714Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities
Q36671655Caveolin-1 overexpression predicts poor disease-free survival of patients with clinically confined renal cell carcinoma
Q28566101Caveolin-1 sensitizes rat pituitary adenoma GH3 cells to bromocriptine induced apoptosis
Q47852031Chromosomal localization, genomic organization, and developmental expression of the murine caveolin gene family (Cav-1, -2, and -3). Cav-1 and Cav-2 genes map to a known tumor suppressor locus (6-A2/7q31).
Q33220432Clonal divergence and genetic heterogeneity in clear cell renal cell carcinomas with sarcomatoid transformation
Q34557827Common fragile site tumor suppressor genes and corresponding mouse models of cancer
Q35575173Construction of a high-resolution physical map of the approximate 1-Mb region of human chromosome 7q31.1-q31.2 harboring a putative tumor suppressor gene
Q33733232DNA copy number losses in human neoplasms
Q40887234Definitive functional evidence for a tumor suppressor gene on human chromosome 7q31.1 neighboring the Fra7G site
Q28359685Down-regulation of caveolin-1, a candidate tumor suppressor gene, in sarcomas
Q28287729Genes encoding human caveolin-1 and -2 are co-localized to the D7S522 locus (7q31.1), a known fragile site (FRA7G) that is frequently deleted in human cancers
Q28304574Identification of ATF-3, caveolin-1, DLC-1, and NM23-H2 as putative antitumorigenic, progesterone-regulated genes for ovarian cancer cells by gene profiling
Q47152490Increased Incidence of Tumors With the IKBKAP Gene Mutation? A Case Report and Review of the Literature
Q24534385Knockout mice reveal a tumor suppressor function for Testin
Q78171358Localization of a novel tumor suppressor gene associated with human oral cancer on chromosome 4q25
Q34813351Loss of caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic mice
Q40705179Loss of heterozygosity on chromosome 7q in in vitro-immortalized human oral keratinocyte cell lines
Q28209312Mutational and functional analyses reveal that ST7 is a highly conserved tumor-suppressor gene on human chromosome 7q31
Q37340493Mutations in the ST7/RAY1/HELG locus rarely occur in primary colorectal, gastric, and hepatocellular carcinomas
Q39658876RNA interference-directed caveolin-1 knockdown sensitizes SN12CPM6 cells to doxorubicin-induced apoptosis and reduces lung metastasis
Q36559674Regulation of Cripto-1 signaling and biological activity by caveolin-1 in mammary epithelial cells
Q28504937ST7-mediated suppression of tumorigenicity of prostate cancer cells is characterized by remodeling of the extracellular matrix
Q56602281Sequence and detailed organization of the human caveolin-1 and -2 genes located near the D7S522 locus (7q31.1)
Q28142435Sequence and detailed organization of the human caveolin-1 and -2 genes located near the D7S522 locus (7q31.1). Methylation of a CpG island in the 5' promoter region of the caveolin-1 gene in human breast cancer cell lines
Q37564565TES inhibits colorectal cancer progression through activation of p38.
Q33890028Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade
Q57788515The Role of Testin in Human Cancers
Q24291361The TES gene at 7q31.1 is methylated in tumours and encodes a novel growth-suppressing LIM domain protein

Search more.