hydroxocobalamin

pharmaceutical drug

DBpedia resource is: http://dbpedia.org/resource/Hydroxocobalamin

Abstract is: Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is a vitamin found in food and used as a dietary supplement. As a supplement it is used to treat vitamin B12 deficiency including pernicious anemia. Other uses include treatment for cyanide poisoning, Leber's optic atrophy, and toxic amblyopia. It is given by injection into a muscle or vein. Side effects are generally few. They may include diarrhea, low blood potassium, allergic reactions, and high blood pressure. Normal doses are considered safe in pregnancy. Hydroxocobalamin is the natural form of vitamin B12 and a member of the cobalamin family of compounds. Hydroxocobalamin, or another form of vitamin B12, are required for the body to make DNA. Hydroxocobalamin was first isolated in 1949. It is on the World Health Organization's List of Essential Medicines. Hydroxocobalamin is available as a generic medication. Commercially it is made using one of a number of types of bacteria.

Wikimedia Commons category is Hydroxocobalamin

C₆₂H₈₉CoN₁₃O₁₅P

hydroxocobalamin is …
instance of (P31):
type of chemical entityQ113145171

sublass of (P279):
heterocyclic compoundQ193430

External links are
P7049AICS Chemical ID (BEING DELETED)13516
P267ATC codeB03BA03
V03AB33
P8072CAB ID40477
P233canonical SMILESCC1=CC2=C(C=C1C)N(C=N2)C3C(C(C(O3)CO)OP(=O)([O-])OC(C)CNC(=O)CCC4(C(C5C6(C(C(C(=N6)C(=C7C(C(C(=N7)C=C8C(C(C(=N8)C(=C4[N-]5)C)CCC(=O)N)(C)C)CCC(=O)N)(C)CC(=O)N)C)CCC(=O)N)(C)CC(=O)N)C)CC(=O)N)C)O.[OH-].[Co+3]
P231CAS Registry Number13422-51-0
P683ChEBI ID27786
P592ChEMBL IDCHEMBL2103737
P661ChemSpider ID21160115
P9272DeCS ID7033
P715DrugBank IDDB00200
P8494DSSTOX compound identifierDTXCID201326774
P3117DSSTox substance IDDTXSID60897433
P232EC number236-533-2
P2566ECHA Substance Infocard ID100.033.198
P9635electronic Essential Medicines List medicine ID121
P646Freebase ID/m/027l0px
P1578Gmelin number5723
P2062HSDB ID3342
P2057Human Metabolome Database IDHMDB0002308
P234InChIInChI=1S/C62H90N13O14P.Co.H2O/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);;1H2/q;+3;/p-3/t31-,34-,35-,36-,37+,41-,52-,53-,56-,57+,59-,60+,61+,62+;;/m1../s1
P235InChIKeyYOZNUFWCRFCGIH-WZHZPDAFSA-K
P2017isomeric SMILES[H]O[Co+]N1\C2=C(C)/C3=N/C(=C\C4=N\C(=C(C)/C5=N[C@@](C)([C@@]1([H])[C@H](CC(=O)N)[C@@]2(C)CCC(=O)NC[C@@H](C)OP(=O)([O-])O[C@H]1[C@@H](O)[C@H](O[C@@H]1CO)N1C=NC2=CC(C)=C(C)C=C12)[C@@](C)(CC(N)=O)[C@@H]5CCC(=O)N)\[C@@](C)(CC(=O)N)[C@@H]4CCC(=O)N)/C(C)(C)[C@@H]3CCC(=O)N
[OH-].[Co+3].C[C@H](CNC(=O)CC[C@]1(C)[C@@H](CC(N)=O)[C@H]2[N-]C1=C(C)C3=NC(=CC4=NC(=C(C)C5=N[C@]2(C)[C@@](C)(CC(N)=O)[C@@H]5CCC(N)=O)[C@@](C)(CC(N)=O)[C@@H]4CCC(N)=O)C(C)(C)[C@@H]3CCC(N)=O)OP([O-])(=O)O[C@@H]6[C@@H](CO)O[C@@H]([C@@H]6O)N7C=NC8=C7C=C(C)C(C)=C8
P665KEGG IDD01027
P486MeSH descriptor IDD006879
P672MeSH tree codeD03.383.129.578.840.437.777.560
D03.633.400.909.437.777.560
D04.345.783.437.777.560
P6366Microsoft Academic ID2776619502
P1748NCI Thesaurus IDC65868
P2115NDF-RT IDN0000146311
P10283OpenAlex IDC2776619502
P11199Probes And Drugs IDPD126919
P662PubChem CID44475014
163191904
P3417Quora topic IDHydroxocobalamin
P3345RxNorm ID5514
P2892UMLS CUIC0020316
P11089UniChem compound ID1065154
P652UNIIQ40X8H422O
P11143WikiProjectMed IDHydroxocobalamin

P3780active ingredient inCyanokitQ29005682
P4250defined daily dose20
P527has part(s)carbonQ623
cobaltQ740
P366has usemedicationQ12140
P3776inhibitor ofnon-structural protein 5 [SARS-CoV-2]Q87917582
P2067mass1345.5670657779997
1345.567065778
P2175medical condition treatedmultiple sclerosisQ8277
pernicious anemiaQ1346016
alcoholic neuropathyQ4062508
diabetic polyneuropathyQ4160985
P2868subject has roleessential medicineQ35456
vitamin BQ183206
hematinicQ10860580
P2275World Health Organisation international non-proprietary namehydroxocobalamin

Reverse relations

drug or therapy used for treatment (P2176)
Q4062508alcoholic neuropathy
Q4160985diabetic polyneuropathy
Q8277multiple sclerosis
Q1346016pernicious anemia

research intervention (P4844)
Q93328895A Randomized Controlled Trial of Mecobalamin Injection and Tablet Treatment Efficacy on Mild to Moderate Diabetic Peripheral Neuropathy
Q61924715A Study in Patients With Amyotrophic Lateral Sclerosis (ALS)
Q86313710A Study of Telaglenastat (CB-839) With Standard-of-Care Chemoimmunotherapy in 1L KEAP1/NRF2-Mutated, Nonsquamous NSCLC
Q63592964A Trial of Vitamin B12 in Septic Shock
Q63581424Administration of Methionine in Patients With Pulmonary Alveolar Proteinosis by Mutation of the MARS Gene.
Q63340720Animal Source Food Supplement and Pregnancy in Vietnam
Q92271913Assessment of Serum Levels of Vitamin D, Vitamin B12 and Folic Acid Among Patients With Lifelong Premature Ejaculation and Non-responding to Dapoxetine Treatment.
Q92271815Autologous Tansfusion REquirements in Bone MArrow Harvest: The ATREMA Study
Q62104864BVAIT: B-Vitamin Atherosclerosis Intervention Trial
Q63588121Can B12 and Folate Levels Predict HPV Penetration in Patients With ASCUS?
Q63337571China Stroke Secondary Prevention Trial
Q87076650Cobalamin Deficiency - Diagnosis and Therapy
Q113894439Do Iron And Vitamin B12 Injections Given Together, Improve Hemoglobin In Patients On Hemodialysis?
Q113887296Effect of Preoperative Intervention With Folic Acid and Vitamin B12 on Postoperative Neurobehavioral Changes in Children
Q90692524Effect of Ultra-short-term Treatment of Patients With Iron Deficiency or Anemia Undergoing Adolescent Scoliosis Correction
Q63401734Effects of Vitamin B12 Treatment in Singers
Q63595269Effects of Vitamin B12 on the Body's Internal Clock
Q63338939Efficacy and Safety Study of Oral Eligen® B12 in Subjects With Low Serum Cobalamin
Q63321002Efficacy of a Novel Multivitamin-Mineral Supplement in Preventing Vitamin Deficiency in Postoperative Bariatric Patients
Q63395028Evaluate the Neuroprotective Effect of Vitamin B6 and Vitamin B12 Against Vincristine Induced Neurotoxicity in Acute Lymphoblastic Leukaemia Patients
Q113939324Evaluation of Aminobutyric Acid, Glutamic Acid, Calcium, Thiamine, Pyridoxine and Cyanocobalamin as Therapy for Vertigo
Q95799537Evaluation of the Relationship Between Zinc Vitamin D and b12 Levels in the Covid-19 Positive Pregnant Women
Q113945344Factors Predicting Erythropoietin Responsiveness in Children on Hemodialysis at Sohag University Hospital
Q94361278GLP-1 Therapy: The Role of IL-6 Signaling and Adipose Tissue Remodeling in Metabolic Response
Q63401761Hemodynamic Effects of Methylene Blue vs Hydroxocobalamin in Patients at Risk of Vasoplegia During Cardiac Surgery
Q86282672Hydroxocobalamin Approach to Reduction of Calprotectin With Butyrate for Ulcerative Colitis Research
Q63320672Impact of Vitamin B12 Supplementation With Iron and Folic Acid on Adolescent Girls
Q94982302International ALLIANCE Study of Therapies to Prevent Progression of COVID-19
Q61957673Intracoronary Administration of Levosimendan in Cardiac Surgery Patients
Q113943304Intrathecal Pemetrexed for Leptomeningeal Metastasis
Q63592958Maternal B12 Supplementation to Improve Infant B12 Deficiency and Neurodevelopment
Q61957366Metanx Effects on Nerve Fiber Density in Neuropathic Diabetics
Q63317194Myo-inositol Versus D-chiro-inositol in the Treatment of Polycystic Ovary Syndrome and Insulin Resistance: Evaluation of Clinical, Metabolic, Endocrine and Ultrasound Parameters
Q63339106Oral Cyanocobalamin (Eligen B12) Bioavailability Study
Q62105171Oral Vitamin B12 Supplementation and Cognitive Performance in Elderly People
Q63320915Oral/Intramuscular B12 to Treat Cobalamin Deficiency
Q62809601Preoperative Vitamin B12 and Folic Acid on POCD in Elderly Non-cardiac Surgical Patients
Q95718285Quadruple Fortified Salt Clinical Trial
Q61914782Randomized Trial of Vitamin B12 in Pregnant Indian Women
Q62030696Recombinant Bovine Basic Fibroblast Growth Factor for the Treatment of Radiation Induced Oral Mucositis
Q63393590Study of Pembrolizumab With Pemetrexed and Oxaliplatin in Chemo-Refractory Metastatic Colorectal Cancer Patients
Q113915916Study of Pemetrexed+Platinum Chemotherapy With or Without Cosibelimab (CK-301) in First Line Metastatic Non-squamous Non-Small Cell Lung Cancer
Q61934419Study of Pralatrexate With Vitamin B12 and Folic Acid in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma
Q63338928The Association Between Religious Origin and Age, and Vitamin B12 and Folic Acid Plasma Levels in Non Jewish Population in Western Galilee
Q61955299To Evaluate the Efficacy and Safety of Vitamin B12 Contains Extract of Lamb's Stomach in Treatment of Chronic Atrophic Gastritis (CAG)
Q105493276Vitamin B12 Biomarker Responses to Supplementation
Q63397229Vitamin B12 Pregnancy Supplementation
Q63229006Vitamin B12 Supplementation During Pregnancy on Cognitive Development
Q113913184Vitamin B12 Supplementation in Diabetic Neuropathy
Q63229188Vitamin B12 for Aromatase Inhibitors Musculoskeletal Symptoms
Q63585497Vitamin B12 for Carpal Tunnel Syndrome
Q63594987Vitamin B6 and B12 in the Treatment of Movement Disorders Induced by Antipsychotics
Q63340438Vitamin B6, B12, Folic Acid and Exercise in Parkinson's Disease

main subject (P921)
Q37652989A double-blind, randomized, comparative study of the use of a combination of uridine triphosphate trisodium, cytidine monophosphate disodium, and hydroxocobalamin, versus isolated treatment with hydroxocobalamin, in patients presenting with compress
Q48893352A fatal case of acute hydrogen sulfide poisoning caused by hydrogen sulfide: hydroxocobalamin therapy for acute hydrogen sulfide poisoning
Q74008026A method for the differentiation of hydroxocobalamin from cyanocobalamin employing the ascorbic acid reaction
Q72039526A method of measuring the serum bindng of hydroxocobalamin
Q90690205A prospective, randomized trial of intravenous hydroxocobalamin versus noradrenaline or saline for treatment of lipopolysaccharide-induced hypotension in a swine model
Q41322643A prospective, randomized trial of intravenous hydroxocobalamin versus whole blood transfusion compared to no treatment for Class III hemorrhagic shock resuscitation in a prehospital swine model
Q71797194Absorption of Cyanocobalamin, Coenzyme B12, Methylcobalamin, and Hydroxocobalamin at Different Dose Levels
Q47609698Acquired methemoglobinemia after hydroxocobalamin administration in a patient with burns and inhalation injury
Q70651687Action of a massive dose of hydroxocobalamin in acute cyanide poisoning. (Apropos of a case)
Q61836298Acute Cyanide Intoxication Treated with a Combination of Hydroxycobalamin, Sodium Nitrite, and Sodium Thiosulfate
Q42120984Acute Cyanide Poisoning: Hydroxocobalamin and Sodium Thiosulfate Treatments with Two Outcomes following One Exposure Event
Q36513393Acute hydrocyanic acid intoxication. Current data on the metabolism of cyanide and treatment by hydroxocobalamin
Q74540951Allergy to hydroxycobalamin, with tolerance of cyanocobalamin
Q50540060An evaluation of the interference of hydroxycobalamin with chemistry and co-oximetry tests on nine commonly used instruments.
Q73136603Anaphylactic reaction to hydroxycobalamin
Q83531940Anaphylactic reaction to hydroxycobalamin with tolerance to cyanocobalamin
Q66837952Anaphylactic shock caused by hydroxocobalamin
Q43228422Anaphylactoid reaction to hydroxycobalamin with tolerance of cyanocobalamin.
Q70618170Antibody to transcobalamin II and B12 binding capacity in patients treated with hydroxocobalamin
Q48612042Antidote treatment for cyanide poisoning with hydroxocobalamin causes bright pink discolouration and chemical-analytical interferences.
Q58965139Applicability of Hydroxocobalamin as a Long-acting Vitamin B12
Q92213214Association between hydroxocobalamin administration and acute kidney injury after smoke inhalation: a multicenter retrospective study
Q85245132BNF recommends hydroxocobalamin rather than cyanocobalamin for vitamin B12 deficiency
Q34456976Biochemical and clinical response to hydroxocobalamin versus cyanocobalamin treatment in patients with methylmalonic acidemia and homocystinuria (cblC).
Q34549609Biosynthesis of 32P-labelled hydroxocobalamin and a study of its behaviour in rats
Q41884090Biphasic modulation of NOS expression, protein and nitrite products by hydroxocobalamin underlies its protective effect in endotoxemic shock: downstream regulation of COX-2, IL-1β, TNF-α, IL-6, and HMGB1 expression
Q42116939Blockade of nitrergic transmission by hydroquinone, hydroxocobalamin and carboxy-PTIO in bovine retractor penis: role of superoxide anion
Q76477755Blood cholesterol and the lipoprotein picture in women of climacteric age treated with hydroxocobalamin and amino acids
Q76479896Blood levels of vitamin B-12 in pregnant women at term and in fetuses after treatment with hydroxocobalamin and cyanocobalamin
Q71089572Body retention of hydroxocobalamin and cyanocobalamin. BNL 6942
Q97900763Burn depth assessment after hydroxocobalamin administration
Q77091973CHEMICAL AND BIOCHEMICAL STUDIES OF VITAMIN B12 AND ITS RELATED COMPOUNDS. 13. COMPARISON OF AVAILABILITIES OF CYANOCOBALAMIN AND HYDROXOCOBALAMIN IN 5,6-DIMETHYLBENZIMIDAZOLYCOBAMIDE COENZYME FORMATION BY PROPIONIBACTERIUM SHERMANII
Q76531148CHEMICAL STUDIES ON VITAMIN B12 AND ITS RELATED COMPOUNDS. III. ON THE BIOLOGICAL ACTIVITY OF HYDROXOCOBALAMIN FOR OCHROMONAS MALHAMENSIS
Q76857068CHEMICAL STUDIES ON VITAMIN B12 AND ITS RELATED COMPOUNDS. VII. PAPER-ELECTROPHORETIC EXAMINATION ON COBAMIDES IN PROPIONIBACTERIUM SHERMANII CELLS CULTIVATED IN THE PRESENCE OF HYDROXOCOBALAMIN OR CYANOCOBALAMIN
Q67260356Carbon monoxide production from hydroxocobalamin by bacteria
Q91689660Cardiopulmonary Bypass Ultrafiltrate Discoloration After Hydroxocobalamin Administration
Q51735573Case report of high-dose hydroxocobalamin in the treatment of vasoplegic syndrome during liver transplantation.
Q71168753Cerebrospinal fluid binding capacity for cyano- and hydroxocobalamin
Q81536496Changes in blood pressure after administration of hydroxocobalamin: relationship to changes in plasma cobalamins-(III) concentrations in healthy volunteers
Q81506708Clarifications regarding interference of hydroxocobalamin with carboxyhemoglobin measurements in victims of smoke inhalation
Q50927442Clinical and biochemical outcome after hydroxocobalamin dose escalation in a series of patients with cobalamin C deficiency.
Q90181456Cobalt Blues: A New Complication of Hydroxocobalamin Therapy for Vasopressor-Resistant Vasoplegia in Patients Treated With Chronic Renal Replacement Therapy?
Q46388407Combined administration of hyperbaric oxygen and hydroxocobalamin improves cerebral metabolism after acute cyanide poisoning in rats
Q73308641Common vitamin B complex agents and folic acid: Part II. Hydroxocobalamin (vitamin B12a [AlphaRedisor; Codroxomin; Droxomin] and folic acid (vitamin B complex [Folvite])
Q46696266Comparative effects of hydroxocobalamin and cyanocobalamin on plasma homocysteine concentrations in end-stage renal disease
Q72326819Comparative study of the Schilling test using cyanocobalamin, hydroxocobalamin and coenzyme B12
Q88289855Comparative study of the tissue distribution of equimolar repeated doses of hydroxocobalamin and cobalt chloride in the rats
Q82996552Comparison of Reductive Dechlorination of Hexachloro-1,3-butadiene in Rhine Sediment and Model Systems with Hydroxocobalamin
Q33538242Comparison of cobinamide to hydroxocobalamin in reversing cyanide physiologic effects in rabbits using diffuse optical spectroscopy monitoring
Q70073306Comparison of hydroxocobalamin and cyanocobalamin in the treatment of pernicious anaemia
Q35873394Comparison of the effects of hydroxocobalamin and oxyhaemoglobin on responses to NO, EDRF and the nitrergic transmitter
Q42289379Comparison of the hemodynamic effects of hydroxocobalamin and cobalt edetate at equipotent cyanide antidotal doses in conscious dogs
Q41247749Complexation of intracellular cyanide by hydroxocobalamin using a human cellular model
Q34718072Congenital methylmalonic aciduria--homocystinuria with megaloblastic anemia: observations on response to hydroxocobalamin and on the effect of homocysteine and methionine on the deoxyuridine suppression test
Q37071694Controlled trial of hydroxocobalamin and riboflavine in Nigerian ataxic neuropathy
Q37849352Cyanide intoxication as part of smoke inhalation--a review on diagnosis and treatment from the emergency perspective.
Q73299171Cyanocobalamin and hydroxocobalamin in vitamin B12 injections
Q69581830Dependence of 5-methyltetrahydrofolate utilization by L5178Y murine leukemia cells in vitro on the presence of hydroxycobalamin and transcobalamin II
Q49277877Depletion of extracellular cysteine with hydroxocobalamin and ascorbate in experimental murine cancer chemotherapy
Q42283961Determination of hydroxocobalamin and cyanocobalamin by derivative spectrophotometry in cyanide poisoning
Q99240765Development of infantile tremor syndrome after initiation of hydroxycobalamin treatment in an infant with a late diagnosis of cobalamin C disorder
Q35870934Differential effects of hydroxocobalamin on NO-mediated relaxations in rat aorta and anococcygeus muscle
Q72615578Differential effects of hydroxocobalamin on relaxations induced by nitrosothiols in rat aorta and anococcygeus muscle
Q70628838Direct spectrophotometric determination of methylcobalamin and hydroxocobalamin in binary mixture. Evaluation of the stability of methylcobalamin in aqueous solutions
Q37052549Discoloration of skin and urine after treatment with hydroxocobalamin for cyanide poisoning
Q68082218Do antidotes have a future? The example of 4-methylpyrazole and hydroxocobalamin
Q71510767Dosage of hydroxocobalamin (Vibeden)
Q44230001Dosage of hydroxocobalamin for vitamin B12 deficiency
Q48709417EEG in assessing hydroxycobalamin therapy in neonatal methylmalonic aciduria with homocystinuria
Q78347706EXPERIENCES WITH A HYDROXOCOBALAMIN PREPARATION (NEUROGRISEVIT) IN NEUROLOGY
Q42921302Effect of ascorbic acid on the degradation of cyanocobalamin and hydroxocobalamin in aqueous solution: a kinetic study
Q73253964Effect of hydroquinone, hydroxocobalamin and carboxy-PTIO on non-adrenergic non-cholinergic nerve mediated relaxations of the rat duodenum
Q41969784Effect of hydroxocobalamin on surface oximetry in nonexposed humans
Q74429426Effect of hydroxocobalamin on vasodilatations to nitrergic transmitter, nitric oxide and endothelium-derived relaxing factor in guinea-pig basilar artery
Q39965207Effect of hydroxycobalamin on the inhibition of cytochrome c oxidase by cyanide. I - In intact mitochondria
Q39998350Effect of hydroxycobalamin on the inhibition of cytochrome c oxidase by cyanide. II - In isolated cytochrome C oxidase
Q72013088Effect of the cyanide antidote hydroxocobalamin on commonly ordered serum chemistry studies
Q53319762Effect of the use of combination uridine triphosphate, cytidine monophosphate, and hydroxycobalamin on the recovery of neurosensory disturbance after bilateral sagittal split osteotomy: a randomized, double-blind trial.
Q72577644Effects of Cobalt or Hydroxycobalamin Supplementation on Vitamin B-12 Content and (S)-Methylmalonyl-CoA Mutase Activity of Tissue from Cobalt-Depleted Sheep
Q70900514Effects of cyanide antidotes used with sodium nitroprusside infusions: sodium thiosulphate and hydroxocobalamin given prophylactically to dogs
Q35028766Effects of hydroxocobalamin and carboxy-PTIO on nitrergic transmission in porcine anococcygeus and retractor penis muscles
Q72658128Effects of hydroxocobalamin and haemoglobin on no-mediated relaxations in the rat anococcygeus muscle
Q50629690Effects of hydroxocobalamin on carboxyhemoglobin measured under physiologic and pathologic conditions.
Q73186612Effects of hydroxocobalamin on nitrergic transmission in rat anococcygeus and bovine retractor penis muscles: sensitivity to light
Q68245005Effects of hydroxocobalamin on rat cardiac papillary muscle
Q71229452Effects of irradiation with gamma rays of cobalt-60 on injectable solutions of cyanocobalamin and hydroxycobalamin
Q36363478Efficacy of Intravenous Cobinamide Versus Hydroxocobalamin or Saline for Treatment of Severe Hydrogen Sulfide Toxicity in a Swine (Sus scrofa) Model
Q90839503Efficacy of Intravenous Hydroxocobalamin for Treatment of Sodium Methanethiolate Exposure in a Swine Model (Sus scrofa) of Severe Methanethiol Toxicity
Q80311689Efficacy of hydroxocobalamin for the treatment of acute cyanide poisoning in adult beagle dogs
Q98569753Efficacy of intramuscular hydroxocobalamin supplementation in cats with cobalamin deficiency and gastrointestinal disease
Q81633278Electronic structure and bonding in hydroxocobalamin
Q100430846Elevated Methemoglobin Levels in a Patient Treated with Hydroxocobalamin After Suspected Cyanide Exposure
Q90000071Elevated Serum Cobalt Concentrations Associated With Hydroxocobalamin Administration for Refractory Vasoplegia
Q80947478Elevated plasma cyanide level after hydroxocobalamin infusion for cyanide poisoning
Q65002117Empiric use of hydroxocobalamin in patients with smoke inhlation injury: Not so fast!
Q39483429Enhanced biotransformation of carbon tetrachloride by Acetobacterium woodii upon addition of hydroxocobalamin and fructose.
Q76496815Erythrocyte levels of vitamin B12 after intramuscular administration of cyanocobalamin, hydroxocobalamin and hydroxocobalamin complex
Q40115142Extreme Hypertriglyceridemia in an Infant with Hemophagocytic Lymphohistiocytosis and Hydroxycobalamin Deficiency
Q87380162Falsely low carboxyhemoglobin level after hydroxocobalamin therapy
Q76587578HYDROXOCOBALAMIN AND CYANOCOBALAMIN IN ADDISONIAN ANAEMIA
Q76848141HYDROXOCOBALAMIN FOR PERNICIOUS ANAEMIA
Q38526442HYDROXOCOBALAMIN IN LARGE DOSES IN RHEUMATIC HYPERALGIA
Q78233231HYDROXOCOBALAMIN: EXCRETION AND RETENTION AFTER PARENTERAL DOSES IN ANEMIC AND NONANEMIC SUBJECTS, WITH REFERENCE TO THE TREATMENT OF VITAMIN B12 DEFICIENCY STATES
Q76670031HYDROXYCOBALAMIN AS A "FLUSHING" DOSE IN THE SCHILLING TEST
Q78345246HYDROXYCOBALAMIN AS AN ANTIDOTE TO ACRYLONITRILE
Q33158589Hemodialysis complications of hydroxocobalamin: a case report
Q41951683Hemodialysis failure secondary to hydroxocobalamin exposure
Q70112792Hemodynamic effects of hydroxocobalamin in conscious dogs
Q94947410Hemodynamics after intraosseous administration of hydroxocobalamin or normal saline in a goat model
Q48658851Hemolysis index to detect degree of hydroxocobalamin interference with common laboratory tests.
Q46926000Hibiscus sabdariffa increases hydroxocobalamin oral bioavailability and clinical efficacy in vitamin B12 deficiency with neurological symptoms
Q44956760High doses of hydroxocobalamin in neurologial pains
Q89769197High-dose hydroxocobalamin achieves biochemical correction and improvement of neuropsychiatric deficits in adults with late onset cobalamin C deficiency
Q35096172High-dose hydroxocobalamin administered after H2S exposure counteracts sulfide-poisoning-induced cardiac depression in sheep
Q33783029High-dose hydroxocobalamin for vasoplegic syndrome causing false blood leak alarm
Q91909086High-dose hydroxocobalamin in end-stage liver disease and liver transplantation
Q72151397Hydroxocobalamin (vitamin B12a) prevents and reverses endotoxin-induced hypotension and mortality in rodents: role of nitric oxide
Q59573134Hydroxocobalamin Quantification in Human Plasma by High-Performance Liquid Chromatography Coupled with Electrospray Tandem Mass Spectrometry in a Pharmacokinetic Study
Q44734531Hydroxocobalamin Therapy of Cyanide Intoxication in Guinea Pigs
Q89960062Hydroxocobalamin Versus Methylene Blue for Vasoplegic Syndrome in Cardiothoracic Surgery: A Retrospective Cohort
Q47266660Hydroxocobalamin With or Without Methylene Blue May Improve Fluid Balance in Critically Ill Patients With Vasoplegic Syndrome After Cardiac Surgery: A Report of Two Cases
Q91911929Hydroxocobalamin administration for treatment of vasoplegic syndrome associated with cardiopulmonary bypass causes red plasma
Q73468525Hydroxocobalamin analysis and pharmacokinetics
Q57695094Hydroxocobalamin and Sodium Thiosulfate versus Sodium Nitrite and Sodium Thiosulfate in Acute Cyanide Toxicity
Q72766373Hydroxocobalamin and cyanocobalamin
Q44412518Hydroxocobalamin and cyanocobalamin interference on co-oximetry based hemoglobin measurements
Q83676706Hydroxocobalamin and epinephrine both improve survival in a swine model of cyanide-induced cardiac arrest
Q72348698Hydroxocobalamin and haemoglobin differentiate between exogenous and neuronal nitric oxide in the rat gastric fundus
Q72682660Hydroxocobalamin and its long-acting effects in treatment of vitamin B 12 deficiency
Q72792274Hydroxocobalamin and sodium thiosulfate interfere negatively with measurement of creatine kinase activity
Q43234397Hydroxocobalamin and sodium thiosulfate versus sodium nitrite and sodium thiosulfate in the treatment of acute cyanide toxicity in a swine (Sus scrofa) model
Q47366095Hydroxocobalamin as a Rescue Treatment for Refractory Vasoplegic Syndrome After Prolonged Cardiopulmonary Bypass
Q36462944Hydroxocobalamin as a cyanide antidote
Q45996959Hydroxocobalamin as a cyanide antidote: safety, efficacy and pharmacokinetics in heavily smoking normal volunteers.
Q41879173Hydroxocobalamin association during cell culture results in pink therapeutic proteins
Q64890052Hydroxocobalamin as a Cause of Oxalate Nephropathy.
Q36341671Hydroxocobalamin dose escalation improves metabolic control in cblC.
Q50196453Hydroxocobalamin for Vasoplegic Syndrome in Liver Transplantation: Restoration of Blood Pressure Without Vasospasm
Q80425538Hydroxocobalamin for acute cyanide poisoning in smoke inhalation
Q28264759Hydroxocobalamin for acute cyanide poisoning: new data from preclinical and clinical studies; new results from the prehospital emergency setting
Q83181686Hydroxocobalamin for cobalamin C: which dosage?
Q69103387Hydroxocobalamin for initial and long-term therapy for vitamin B12 deficiency
Q81457893Hydroxocobalamin for poisoning caused by ingestion of potassium cyanide: a case study
Q36837590Hydroxocobalamin for severe acute cyanide poisoning by ingestion or inhalation
Q91455551Hydroxocobalamin for the Treatment of Vasoplegia: A Review of Current Literature and Considerations for Use
Q46183590Hydroxocobalamin for the treatment of cardiac surgery-associated vasoplegia: a case series
Q101136322Hydroxocobalamin for the treatment of refractory intraoperative vasoplegia in a patient with history of squamous cell carcinoma and radiation
Q46038246Hydroxocobalamin hinders hemodialysis.
Q39642909Hydroxocobalamin in chronic cyanide poisoning
Q28279530Hydroxocobalamin in cyanide poisoning
Q71145524Hydroxocobalamin in otoneuropathies
Q53742528Hydroxocobalamin in the treatment of Leber's hereditary optic atrophy.
Q92175423Hydroxocobalamin in the treatment of vasodilatory shock
Q104102733Hydroxocobalamin mimicking intravascular hemolysis in therapeutic plasma exchange
Q44037448Hydroxocobalamin reduces hyperhomocysteinemia in end-stage renal disease
Q50481005Hydroxocobalamin supplementation and erythropoisis stimulating agent hyporesponsiveness in haemodialysis patients.
Q35029907Hydroxocobalamin treatment of acute cyanide poisoning from apricot kernels
Q84800712Hydroxocobalamin treatment of acute cyanide poisoning from apricot kernels
Q42582528Hydroxocobalamin treatment of acute cyanide poisoning with a jewellery-cleaning solution
Q39855125Hydroxocobalamin treatment of hypercyanemia and hypercyanuria following sciatic nerve compression in rabbits
Q91310755Hydroxocobalamin treatment of refractory vasoplegia in patients with mechanical circulatory support
Q44688158Hydroxocobalamin uptake into the cerebrospinal fluid after nasal and intravenous delivery in rats and humans
Q73307288Hydroxocobalamin versus cyanocobalamin
Q70074719Hydroxocobalamin versus cyanocobalamin in the treatment of tobacco amblyopia
Q83565449Hydroxocobalamin versus sodium thiosulfate for the treatment of acute cyanide toxicity in a swine (Sus scrofa) model
Q80726021Hydroxocobalamin versus thiosulfate for cyanide poisoning
Q57907208Hydroxocobalamin vs cobalt toxicity on rat cardiac and diaphragmatic muscles
Q74786259Hydroxocobalamin, a nitric oxide scavenger, in the prophylaxis of migraine: an open, pilot study
Q79397182Hydroxocobalamin. I. Blood levels and urinary excretion of vitamin B12 in man after a single parenteral dose of aqueous hydroxocobalamin, aqueous cyanocobalamin and cyanocobalamin zinc-tannate complex
Q72756098Hydroxocobalamin. IV. Biological half-life of hydroxocobalamin in the human liver
Q71167489Hydroxocobalamin. V. Prolonged maintenance of high vitamin B12 blood levels following a short course of hydroxocobalamin injections
Q72866955Hydroxocobalamin. VI. Comparison of Intestinal Absorption in Man Of Large Doses of Hydroxocobalamin and Cyanocobalamin
Q82774138Hydroxocobalamin: a better cyanide antidote
Q34269208Hydroxocobalamin: improved public health readiness for cyanide disasters
Q47867966Hydroxocobalamin: treatment for smoke inhalation-associated cyanide poisoning. Meeting the needs of fire victims.
Q69402859Hydroxocobalamine in cyanide poisoning
Q64096676Hydroxycobalamin Reveals the Involvement of Hydrogen Sulfide in the Hypoxic Responses of Rat Carotid Body Chemoreceptor Cells
Q57070043Hydroxycobalamin catalyzes the oxidation of diethyldithiocarbamate and increases its cytotoxicity independently of copper ions
Q42592175Hydroxycobalamin for ethambutol-induced optic neuropathy
Q47787349Hydroxycobalamin, hyperbaric oxygen and cyanide poisoning.
Q48235076Hyperbaric oxygen therapy or hydroxycobalamin attenuates surges in brain interstitial lactate and glucose; and hyperbaric oxygen improves respiratory status in cyanide-intoxicated rats.
Q67517344IGE-mediated reaction to hydroxocobalamin injection in patient with pernicious anaemia
Q89994447Iatrogenic pediatric hydroxocobalamin overdose
Q73810533In situ X-ray absorption spectroelectrochemical study of hydroxocobalamin
Q100417130In vitro comparison of hydroxocobalamin (B12a) and the mitochondrial directed therapy by a succinate prodrug in a cellular model of cyanide poisoning
Q48839514In vitro demonstration of the antidotal efficacy of hydroxocobalamin in cyanide poisoning.
Q46909794In vitro effects of hydroxocobalamin after cyanide intoxication
Q48177690Increase in circulating holotranscobalamin after oral administration of cyanocobalamin or hydroxocobalamin in healthy adults with low and normal cobalamin status.
Q74310559Inhibitory actions of hydroxocobalamin, cyanocobalamin, and folic acid on the ultraviolet light-induced relaxation of the frog upper oesophageal strip
Q71750540Interactions between hydroxocobalamin and nitric oxide (NO): evidence for a redox reaction between NO and reduced cobalamin and reversible NO binding to oxidized cobalamin
Q43878387Interference of hydroxocobalamine treatment on commun biochemical determinations
Q81506704Interference of the cyanide antidote hydroxocobalamin with carboxyhemoglobin measurements should not limit clinical use in suspected or confirmed cyanide poisoning
Q35008986Intracellular binding of radioactive hydroxocobalamin to cobalamin-dependent apoenzymes in rat liver
Q40216043Intraosseous hydroxocobalamin versus intravenous hydroxocobalamin compared to intraosseous whole blood or no treatment for hemorrhagic shock in a swine model
Q47739435Intraosseous versus intravenous infusion of hydroxocobalamin for the treatment of acute severe cyanide toxicity in a Swine model
Q90003275Intravenous Hydroxocobalamin Versus Hextend Versus Control for Class III Hemorrhage Resuscitation in a Prehospital Swine Model
Q35805162Intravenous cobinamide versus hydroxocobalamin for acute treatment of severe cyanide poisoning in a swine (Sus scrofa) model
Q86558269Intravenous cobinamide versus hydroxocobalamin for acute treatment of severe cyanide poisoning in a swine (Sus scrofa) model
Q88636632Intravenous hydroxocobalamin and crystal nephropathy
Q72075211Intravenous treatment with betamethasone phosphate and hydroxycobalamin in some pain syndromes caused by radicular diseases
Q80356936Is hydroxocobalamin safe and effective for smoke inhalation? Searching for guidance in the haze
Q83487073Laboratory interferences with the newer cyanide antidote: hydroxocobalamin
Q49829889Lactate blood measurement in acute cyanide poisoning: effect of preanalytical delay and hydroxocobalamin uses as treatment
Q48255460Letter in response to "Acquired methemoglobinemia after hydroxocobalamin administration in a patient with burns and inhalation injury".
Q42235665Letter: Anaphylactic shock due to hydroxocobalamine
Q47773506Liquid chromatographic mass spectrometric (LC/MS/MS) determination of plasma hydroxocobalamin and cyanocobalamin concentrations after hydroxocobalamin antidote treatment for cyanide poisoning
Q87580557Long-lasting atypical acneiform eruption with prominent comedones induced by hydroxocobalamin (vitamin B12 )
Q39543565Lymphocyte subpopulations in patients with hydroxocobalamin responsive megaloblastic anaemia
Q93788892Maintenance therapy of pernicious anaemia. Comparison of cyanocobalamin, hydroxocobalamin and a cyanocobalamin-zinc-tannate complex
Q79018450Mechanism of the long-acting effect of hydroxocobalamine
Q69573947Metabolic fate of 57Co-labeled hydroxocobalamin and 57Co-labeled 5,6-dimethylbenzimidazolylcobamide coenzyme in rats
Q90868926Methylene Blue Monotherapy Compared With Combination Therapy With Hydroxocobalamin for the Treatment of Refractory Vasoplegic Syndrome: ARetrospective Cohort Study
Q36847813Microbial degradation of corrinoids. VI. Reduction of hydroxocobalamin by cell-free particles from Pseudomonas rubescens
Q40181879Mitochondrial metabolism of hydroxocobalamin: Synthesis of adenosylcobalamin by intact rat liver mitochondria
Q92468330Modest and variable efficacy of pre-exposure hydroxocobalamin and dicobalt edetate in a porcine model of acute cyanide salt poisoning
Q70874304Monitoring of cyanocobalamin and hydroxocobalamin during treatment of cyanide intoxication
Q38521346Motor and psychomotor troubles and metabolic equilibrium in senescence. Treatment by high dose hydroxocobalamine
Q95560011Multicomponent spectrometric assay of cyanocobalamin and its photoproduct hydroxocobalamin in the presence of ascorbic acid in photolyzed solutions
Q82269616Multicomponent spectrophotometric assay of cyanocobalamin, hydroxocobalamin and riboflavin
Q35803111Nasal absorption of hydroxocobalamin in healthy elderly adults
Q71152327Nature of vitamin B 12 binding. I. Covalent coupling of hydroxocobalamin to soluble and insoluble carriers
Q71731367Neurological treatment using hydroxocobalamin in high doses. Statistics and comments
Q80311694Nitric oxide scavenging by hydroxocobalamin may account for its hemodynamic profile
Q34434617Normalization of plasma vitamin B12 concentration by intranasal hydroxocobalamin in vitamin B12-deficient patients
Q71614296Occurrence of antibodies against transcobalamin II in relation to the number of and the intervals between depot therapy with hydroxocobalamin
Q90938706Off to the Races: Comparison of Excited State Dynamics in Vitamin B12 Derivatives Hydroxocobalamin and Aquocobalamin
Q72851740On the different capacities of hydroxycobalamin and dimethyl-5,6-benzimidazole-cobamide-coenzyme to reduce some adverse effects of adrenal cortex hormones
Q37612806On the different capacity of hydroxocobalamin and 5,6-dimethyl-benzimidazole-coenzyme to reduct the harmful effects of corticoids
Q71961150On the properties of hydroxocobalamine base
Q72949663On the use of the vitamin combination S-benzoyl-thiamine monophosphate, pyridoxine hydrochloride and hydroxocobalamin in some neurological syndromes
Q72345711On the use of vitamin B 12 in children with brain damage. Comparative studies of the serum level in caynacobalamin and hydroxycobalamin
Q46870162Optimizing the dose of hydroxocobalamin in cobalamin C (cblC) defect.
Q102327182Outcomes after the administration of hydroxocobalamin
Q93189516Parenteral hydroxocobalamin dose intensification in five patients with different types of early onset intracellular cobalamin defects: Clinical and biochemical responses
Q72208615Patient variation in pernicious anaemia, as shown in a clinical trial of cyanocobalamin, hydroxocobalamin and cyanocobalamin--zinc tannate
Q38108105Patterns of cyanide antidote use since regulatory approval of hydroxocobalamin in the United States
Q96430990Pernicious anaemia: self-administration of hydroxocobalamin in the covid-19 crisis
Q72016956Pharmacokinetics of hydroxocobalamin in dogs
Q71238092Pharmacokinetics of hydroxocobalamin in smoke inhalation victims
Q71145527Pharmacological effects of hydroxocobalamin. Antagonism between hydroxocobalamin and cyanates
Q53253194Photostability of Hydroxocobalamin: Ultrafast Excited State Dynamics and Computational Studies.
Q33268564Potential interference by hydroxocobalamin on cooximetry hemoglobin measurements during cyanide and smoke inhalation treatments
Q36149780Preclinical evaluation of injectable reduced hydroxocobalamin as an antidote to acute carbon monoxide poisoning
Q47848410Prehospital administration of hydroxocobalamin for smoke inhalation-associated cyanide poisoning: 8 years of experience in the Paris Fire Brigade
Q41923895Prehospital hydroxocobalamin for inhalation injury and cyanide toxicity in the United States - analysis of a database and survey of ems providers
Q81538824Prevention of hydrogen sulfide (H2S)-induced mouse lethality and cytotoxicity by hydroxocobalamin (vitamin B(12a))
Q67302021Prevention of nitroprusside-induced cyanide toxicity with hydroxocobalamin
Q55013626Prospective long-term evaluation of parenteral hydroxocobalamin supplementation in juvenile beagles with selective intestinal cobalamin malabsorption (Imerslund-Gräsbeck syndrome).
Q47840973Prospective study of hydroxocobalamin for acute cyanide poisoning in smoke inhalation
Q48204767Red urinary discolouration following hydroxocobalamin treatment for vasoplegic syndrome
Q89945934Red urine after hydroxycobalamin administration
Q45125482Reductive dechlorination of alpha-, beta-, delta-, and gamma-hexachlorocyclohexane isomers by hydroxocobalamin in the presence of either dithiothreitol or titanium(III) citrate as reducing agents
Q42935245Reductive dechlorination of α-, β-, γ-, and δ-hexachlorocyclohexane isomers with hydroxocobalamin, in soil slurry systems
Q42277553Relation of blood cyanide to plasma cyanocobalamin concentration after a fixed dose of hydroxocobalamin in cyanide poisoning
Q53708914Renal excretion of hydroxocobalamin in man.
Q80425542Reply to: "Is hydroxocobalamin safe and effective for smoke inhalation? Searching for guidance in the haze"
Q100661880Rescue of Nimodipine-Induced Refractory Vasoplegia With Hydroxocobalamin in Subarachnoid Hemorrhage: A Case Report
Q72856746Retention and Distribution of B12 Activity, and Requirement for B12, Following Parenteral Administration of Hydroxocobalamin (Vibeden®)
Q53719908Retention of cyanocobalamin, hydroxocobalamin, and coenzyme B12 after parenteral administration.
Q79520337Retention of injected hydroxocobalamin versus cyanocobalamin versus liver extract-bound cobalamin
Q51546095Risk of oxalate nephropathy with the use of cyanide antidote hydroxocobalamin in critically ill burn patients.
Q28275698Role of hydroxocobalamin in acute cyanide poisoning
Q55640466Role of vegetarianism, smoking, and hydroxocobalamin in optic neuritis.
Q76706694STABILITY OF AQUEOUS SOLUTIONS OF HYDROXOCOBALAMIN
Q76686843STABILITY OF THE COBALAMIN MOIETY IN BUFFERED AQUEOUS SOLUTIONS OF HYDROXOCOBALAMIN
Q76866340STUDIES ON VITAMIN B12 RETENTION. COMPARISON OF RETENTION FOLLOWING INTRAMUSCULAR INJECTION OF CYANOCOBALAMIN AND HYDROXOCOBALAMIN
Q50720526Safety of hydroxocobalamin in healthy volunteers in a randomized, placebo-controlled study.
Q28365355Sensitivity to cyanocobalamin and hydroxocobalamin
Q72909033Separation of hydroxocobalamin and cyanocobalamin by thin-layer chromatography
Q72039528Serum binding of hydroxocobalamin
Q70641082Severe algia of the ORL sphere and hydroxocobalamin in massive doses
Q72032304Simultaneous determination of hydroxocobalamin and its cyanide complex cyanocobalamin in human plasma by high-performance liquid chromatography. Application to pharmacokinetic studies after high-dose hydroxocobalamin as an antidote for severe cyanid
Q34778344Single-molecule conformational dynamics of a biologically functional hydroxocobalamin riboswitch
Q71001550Sodium nitroprusside: comparison of the antidotal effect of hydroxocobalamin and sodium thiosulfate in rabbits
Q69896268Sodium nitroprusside: pharmacological aspects of its interaction with hydroxocobalamin and thiosulphate
Q28273515Sodium thiosulfate or hydroxocobalamin for the empiric treatment of cyanide poisoning?
Q81536491Spectrophotometry of hydroxocobalamin and hemoglobin reveals production of an unanticipated methemoglobin variant
Q72731061Studies on intestinal absorption of hydroxocobalamin
Q72362100Study of the mechanisms involved in hydroxocobalamin interference with determination of some biochemical parameters
Q57115535Successful Renal Transplantation after Presumed Cyanide Toxicity Treated with Hydroxocobalamin and Review of the Literature
Q40254423Successful Use of Hydroxocobalamin and Sodium Thiosulfate in Acute Cyanide Poisoning: A Case Report with Follow-up
Q33144518Syncope following intramuscular injection of hydroxocobalamin in a paraplegic patient: indication for oral administration of cyanocobalamin in spinal cord injury patients
Q76850042THE IONIZATION OF CYANOCOBALAMIN, HYDROXOCOBALAMIN, HYDROXOCOBALAMIN HYDROCHLORIDE, AND HYDROXOCOBALAMIN DIHYDROBROMIDE
Q76736223THERAPEUTIC APPLICATIONS OF HYDROXOCOBALAMINE, THIAMINE AND PYRIDOXINE IN A CONJOINED FORM
Q38526189TREATMENT OF RHEUMATIC HYPERALGIAS WITH HYDROXOCOBALAMINE (VIT. B 12 B) 5000 MICROGRAMS)
Q70785750The antidote effect of thiosulphate and hydroxocobalamin in formation of nitroprusside intoxication of rabbits
Q71701191The assay of hydroxocobalamin in urine--a possible source of error
Q71255544The availability of therapeutic hydroxocobalamin to cells
Q50103494The curious tale of perioperative precision medicine: a story of hydroxocobalamin and cardiac surgery-associated vasoplegia.
Q41345896The effect of hydroxocobalamin on the nitroprusside-induced relaxation of rat aortic preparations
Q72608857The nature of the radioactive material in urine after parenteral 57Co hydroxocobalamin
Q44511082The phagocytic activity of the reticuloendothelial system for colloidal carbon in rats undergoing a treatment with vitamin B complex, with cyanocobalamin, with hydroxycobalamin and with cobamamide
Q79420888The preparation of radioactive hydroxocobalamin
Q44997586The use of high-dose hydroxocobalamin for vasoplegic syndrome.
Q100301437The use of hydroxocobalamin for vasoplegic syndrome in left ventricular assist device patients
Q51632404The use of hydroxocobalamin in the Schilling test.
Q71086717The use of hydroxocobalamin in the prophylaxis and treatment of nitroprusside-induced cyanide toxicity
Q47148759The use of intravenous hydroxocobalamin as a rescue in methylene blue-resistant vasoplegic syndrome in cardiac surgery
Q54255536Therapeutic concentrations of hydroxocobalamin interferes with several spectrophotometric assays on the Beckman Coulter DxC and AU680 chemistry analyzers.
Q72919998Thin-layer chromatography of cyanocobalamin, hydroxocobalamin and B12 coenzymes
Q46452265Thiosulphate and hydroxocobalamin prophylaxis in progressive cyanide poisoning in guinea-pigs
Q27629181Three-dimensional structure of ATP:corrinoid adenosyltransferase from Salmonella typhimurium in its free state, complexed with MgATP, or complexed with hydroxycobalamin and MgATP
Q42289196Transcobalamin II mediated delivery of albumin-bound hydroxocobalamin to human liver cells
Q47349414Treatment of Vasoplegic Syndrome With Intravenous Hydroxocobalamin During Liver Transplantation
Q53814668Treatment of viral hepatitis with an association of folinic acid and hydroxycobalamin
Q76995389USE OF HYDROXOCOBALAMIN IN EXPERIMENTAL CYANIDE POISONING
Q73151017Unavailable hydroxocobalamin in injectable form
Q93093107Unexpected Complication of Hydroxocobalamin Administration for Refractory Vasoplegia in Orthotopic Liver Transplant: A Case Report
Q67835314Uptake of hydroxocobalamin by rat liver mitochondria. Binding to a mitochondrial protein
Q71324647Urinary excretion of hydroxocobalamine and cyanocobalamine after oral administration of large doses
Q93092343Use of High-Dose Hydroxocobalamin for Septic Shock: A Case Report
Q89443740Use of Hydroxocobalamin (Vitamin B12a) in Patients With Vasopressor Refractory Hypotension After Cardiopulmonary Bypass: A Case Series
Q103023628Use of Intravenous Hydroxocobalamin for Vasoplegic Syndrome in Simultaneous Liver-Kidney Transplant: A Case Report
Q71112094Use of high concentrations of hydroxocobalamin in the treatment of anti-rabies post vaccination reactions
Q71145537Use of hydroxocobalamin in deficiency (alcoholic) polyneuritis
Q71145541Use of hydroxocobalamin in rheumatic pains
Q38935470Utility and outcomes of hydroxocobalamin use in smoke inhalation patients
Q71382157Value of using 5000 mcg hydroxocobalamin in treatment of visual deficiency in glaucomatous optic atrophy
Q41328011Vitamin B-12b as an antidote for over-sedation
Q54332911Wine-Colored Plasma and Urine from Hydroxocobalamin Treatment.
Q79646098[Action of hydroxocobalamin in the prevention of protein catabolism caused by prednisone. Preliminary note.]
Q79480767[Action of hydroxycobalamin on the protein metabolism of nerve cells. Histochemical study of te alkaline phosphatases in fatigued animals.]
Q72001859[Betamethasone associated with hydroxocobalamin in the treatment of neuralgic syndromes]
Q78427697[CLINICAL APPLICATION OF A NEW VITAMIN B-12 DERIVATIVE (HYDROXOCOBALAMIN) WITH MASSIVE DOSES TO NERVOUS SYSTEM DISEASES.]
Q76855849[CLINICAL TRIAL OF A NEW VITAMIN B 12 DERIVATIVE, HYDROXOCOBALAMIN, IN NEUROPSYCHIATRIC DISEASES.]
Q72399489[Clinical observations on the therapeutic activity of dexamethasone associated with hydroxocobalamin]
Q54577462[Clinical tests of the anti-analgesic action of hydroxocobalamin in lumbar and sciatic pains]
Q69926809[Comparative study of the effects of hydroxocobalamin and cyanocobalamin on rheumatic pains. (Double blind test)]
Q53768085[Contribution to the study of hydroxocobalamin in neurology. (Apropos of 18 cases)]
Q79505475[Contribution to the study of hydroxycobalamin therapy of neurological deficiency syndromes in alcoholics.]
Q71930861[Determination of the traces of hydroxocobalamin (vitamin B 12a) in the presence of cyanocobalamin (vitamin B 12)]
Q71145530[Drug therapy of diabetic neuropathies using high doses of hydroxocobalamin]
Q72173226[Effect of vitamin B12 (hydroxocobalamine) on intraocular pressure]
Q69414224[Hemodynamic effect of hydroxocobalamin in the chronically implanted conscious dog]
Q70402129[Hydroxocobalamin and corneal cicatrization. Experimental study and application to tolerance of contact lenses]
Q71145534[Hydroxocobalamin in clinical pains]
Q79460325[Hydroxocobalamin in the treatment of hydorcyanic acid poisoning.]
Q79491641[Hydroxocobalamin, vitamin B12-binding factors and the intrinsic factor.]
Q72797521[Hydroxocobalamine in long-term treatment of pernicious anemia]
Q79426115[Hydroxocobalamine: natural depot vitamin B-12]
Q74727235[Hydroxycobalamin in the treatment of poisoning by both carbon monoxide and cyanide]
Q50968436[Methylene blue as an inhibitor of the reduction of hydroxocobalamin by carbon monoxide].
Q68942153[Neurophysiological findings in cats with large doses of hydroxocobalamine base]
Q78404645[ON HYDROXOCOBALAMIN THERAPY.]
Q79460331[On the subject of the therapeutic value of hydroxocobalamin in hydrocyanic acid poisoning.]
Q72962491[On the treatment of pustulosis palmarum et plantarum. Clinical experience with hydroxocobalamin]
Q72414945[Possibilities of 5000 gamma hydroxocobalamin in child psychiatry]
Q68919328[Potassium cyanide poisoning treated with hydroxocobalamin]
Q79646093[Research on the neurotropic action of hydroxocobalamin and its combination with pyridoxine HCl or with thiamine propvldisulfide. Preliminary note.]
Q52268622[Results of the oral administration of a compound of amino acids with hydroxocobalamin in a series of aged subjects]
Q72791391[Retention, distribution and uptake of vitamin B 12 following parenteral administration of hydroxycobalamin (Vibeden)]
Q76496810[Stability of aqueous solutions of hydroxocobalamin. I. Influence of sterilization heat on the stability of aqueous solutions of hydroxocobalamin and comparison with cyanobalamin solutions and in the presence of other vitamins in the B group and gly
Q76496811[Stability of aqueous solutions of hydroxocobalamin. II. Stability time of aqueous solutions of hydroxocobalamin at various temperatures and comparison with cyanocobalamin solutions, in the presence of other vitamins in the B group and glycine]
Q76496813[Stability of aqueous solutions of hydroxocobalamin. III. Stability time of sugar and sorbitol solutions of hydroxocobalamin at various temperatures and comparison with analogous solutions of cyanocobalamin, in the presence of other vitamins of the
Q72584793[Stabilization of hydroxocobalamin in liver extracts]
Q72180105[Studies on intestinal absorption of hydroxocobalamin. II. Biological half life of hydroxocobalamin in small intestinal wall]
Q68577551[Study of the therapeutic action of a combination of vitamins B1, B6 and hydroxocobalamin in large doses]
Q72839682[The Schilling test performed with Co58-hydroxocobalamin. Considerations on the kinetics of cyano- and hydroxocobalamin]
Q79376023[The use of hydroxocobalamine (vitamin B-12a) in the treatment of hydrocyanic acid poisoning.]
Q68415588[Therapeutic trials with hydroxocobalamin at 5000 gamma in pain of the O.R.L. area]
Q70067274[Treatment of reflex neurodystrophic syndromes of lumbar osteochondrosis using hydroxycobalamin injections]
Q68542152[Treatment of vertebragenous pain and sensitivity disorders using high doses of hydroxocobalamin]
Q83178963[Treatment with hydroxocobalamin for cyanide poisoning: a rare cause of pseudohematuria]
Q73222095[Vitamin B12-variant in cyanide poisoning. Hydroxycobalamin is a new effective antidote]

Q29005682Cyanokithas active ingredientP3781
Q37155World Health Organization Model List of Essential Medicineshas part(s)P527

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