Vitamin E supplementation improves endothelial function in type I diabetes mellitus: a randomized, placebo-controlled study

scientific article published on 01 July 2000

Vitamin E supplementation improves endothelial function in type I diabetes mellitus: a randomized, placebo-controlled study is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0735-1097(00)00720-8
P698PubMed publication ID10898419

P50authorRichard O'BrienQ57081567
P2093author name stringI T Meredith
K L Berry
R A Skyrme-Jones
P2860cites workRandomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)Q71060539
Endothelial relaxation is disturbed by oxidative stress in the diabetic rat heart: influence of tocopherol as antioxidantQ71215633
Impaired vascular reactivity in insulin-dependent diabetes mellitus is related to disease duration and low density lipoprotein cholesterol levelsQ71442222
Chronic vitamin E treatment prevents defective endothelium-dependent relaxation in diabetic rat aortaQ71482551
Lack of effect of vitamin E administration on basal nitric oxide function in male smokers and non-smokersQ71572342
Antioxidants inhibit the expression of intercellular cell adhesion molecule-1 and vascular cell adhesion molecule-1 induced by oxidized LDL on human umbilical vein endothelial cellsQ71869353
Characterization of the mechanism for the chronic activation of diacylglycerol-protein kinase C pathway in diabetes and hypergalactosemiaQ72150727
The effect of probucol and vitamin E treatment on the oxidation of low-density lipoprotein and forearm vascular responses in humansQ72629798
Normalization of diacylglycerol-protein kinase C activation by vitamin E in aorta of diabetic rats and cultured rat smooth muscle cells exposed to elevated glucose levelsQ72717727
Effect of antioxidant vitamins on low density lipoprotein oxidation and impaired endothelium-dependent vasodilation in patients with hypercholesterolemiaQ72811816
Lack of effect of vitamin E on L-arginine-responsive endothelial dysfunction in patients with mild hypercholesterolaemia and coronary artery diseaseQ74426928
Beneficial effect of vitamin E administration on nitric oxide function in subjects with hypercholesterolaemiaQ77217158
Effect of oral vitamin E (alpha-tocopherol) supplementation on vascular endothelial function in Type 2 diabetes mellitusQ77374241
Plasma alpha-tocopherol and coronary endothelium-dependent vasodilator functionQ78017102
Ubiquinol-10 protects human low density lipoprotein more efficiently against lipid peroxidation than does alpha-tocopherolQ24564131
The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research GroupQ27861088
Low-dose alpha-tocopherol improves and high-dose alpha-tocopherol worsens endothelial vasodilator function in cholesterol-fed rabbits.Q34127841
Alpha-tocopherol inhibits agonist-induced monocytic cell adhesion to cultured human endothelial cellsQ34228843
Vitamin E consumption and the risk of coronary heart disease in men.Q34363912
Inactivation of endothelial derived relaxing factor by oxidized lipoproteinsQ35595749
Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin-dependent diabetes mellitusQ37350875
Vascular incorporation of alpha-tocopherol prevents endothelial dysfunction due to oxidized LDL by inhibiting protein kinase C stimulationQ37357656
Improvement in endothelial function by angiotensin converting enzyme inhibition in insulin-dependent diabetes mellitusQ37370706
Role of oxidative stress in development of complications in diabetesQ37681089
Monocyte adhesion and transmigration in atherosclerosis.Q40760531
Hyperglycemic pseudohypoxia and diabetic complications.Q40908737
Lipids and lipoproteins predicting coronary heart disease mortality and morbidity in patients with non-insulin-dependent diabetesQ41065494
Alpha-tocopherol (vitamin E) regulates vascular smooth muscle cell proliferation and protein kinase C activityQ41689122
Protein kinase C activation and its role in the development of vascular complications in diabetes mellitusQ41700541
Regulation of endothelial constitutive nitric oxide synthase by protein kinase C.Q42477136
Vitamin E administration improves impairment of endothelium-dependent vasodilation in patients with coronary spastic anginaQ42538178
Effect of supplementary antioxidant vitamin intake on carotid arterial wall intima-media thickness in a controlled clinical trial of cholesterol lowering.Q45977266
Endothelial vasodilator function is related to low-density lipoprotein particle size and low-density lipoprotein vitamin E content in type 1 diabetes.Q47246787
Vitamin E consumption and the risk of coronary disease in womenQ50126258
Long-term estrogen therapy improves vascular function in male to female transsexuals.Q50952179
Improvement of endothelial vasomotor dysfunction by treatment with alpha-tocopherol in patients with high remnant lipoproteins levels.Q51563312
Hyperinsulinemia as an independent risk factor for ischemic heart disease.Q51581884
A rapid method for measurement of the susceptibility to oxidation of low-density lipoprotein.Q51650932
Vitamin E improves arterial compliance in middle-aged men and women.Q54078862
Effect of vitamin E on endothelial vasodilator function in patients with hypercholesterolemia, chronic smoking or both.Q54105580
Vitamin C improves endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus.Q54144635
Dietary vitamin E increases the resistance to lipoprotein oxidation and attenuates endothelial dysfunction in the cholesterol-fed rabbit.Q54194163
Impaired endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus.Q54225577
Role of vitamin E in preventing the oxidation of low-density lipoprotein.Q54305502
Vitamin E normalizes diacylglycerol-protein kinase C activation induced by hyperglycemia in rat vascular tissues.Q54532174
Additional benefit of vitamin E supplementation to simvastatin therapy on vasoreactivity of the brachial artery of hypercholesterolemic menQ58071804
Pharmacologic doses of vitamin E improve insulin action in healthy subjects and non-insulin-dependent diabetic patientsQ58829456
Impairment of endothelium-dependent arterial relaxation by lysolecithin in modified low-density lipoproteinsQ59060592
Effects of native and oxidized low density lipoproteins on formation and inactivation of endothelium-derived relaxing factorQ68183273
Increased aortic stiffness in patients with type 1 (insulin-dependent) diabetes mellitusQ69393731
Single vertical spin density gradient ultracentrifugationQ69553503
Simultaneous measurement of retinol and alpha-tocopherol in human serum by high-performance liquid chromatography with ultraviolet detectionQ69593242
Continuous monitoring of in vitro oxidation of human low density lipoproteinQ69611707
Inverse relation between the concentration of low-density-lipoprotein vitamin E and severity of coronary artery diseaseQ71003999
P433issue1
P407language of work or nameEnglishQ1860
P921main subjecttype-1 diabetesQ124407
placeboQ269829
P304page(s)94-102
P577publication date2000-07-01
P1433published inJournal of the American College of CardiologyQ2984355
P1476titleVitamin E supplementation improves endothelial function in type I diabetes mellitus: a randomized, placebo-controlled study
P478volume36

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Q44927546Early vitamin E supplementation attenuates diabetes-associated vascular dysfunction and the rise in protein kinase C-beta in mesenteric artery and ameliorates wall stiffness in femoral artery of Wistar rats.
Q28346698Effect of M40403 treatment of diabetic rats on endoneurial blood flow, motor nerve conduction velocity and vascular function of epineurial arterioles of the sciatic nerve
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