Effect of tauroursodeoxycholic acid on bile-acid-induced apoptosis and cytolysis in rat hepatocytes

scientific article published on 01 January 1998

Effect of tauroursodeoxycholic acid on bile-acid-induced apoptosis and cytolysis in rat hepatocytes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0168-8278(98)80208-0
P698PubMed publication ID9537871

P50authorWolfgang StremmelQ50772068
P2093author name stringA Stiehl
C Benz
P Sauer
H D Riedel
U Töx
S Angermüller
P Klöters-Plachky
P2860cites workA multicenter, controlled trial of ursodiol for the treatment of primary biliary cirrhosis. UDCA-PBC Study GroupQ28243457
Dose-dependent induction of apoptosis in human tumour cell lines by widely diverging stimuli.Q34094129
Increases of intracellular magnesium promote glycodeoxycholate-induced apoptosis in rat hepatocytesQ35824326
Effects of bile salts on the plasma membranes of isolated rat hepatocytesQ41900837
Conjugates of ursodeoxycholate protect against cytotoxicity of more hydrophobic bile salts: in vitro studies in rat hepatocytes and human erythrocytesQ44946866
Ursodeoxycholate conjugates protect against disruption of cholesterol-rich membranes by bile salts.Q45089631
Ursodeoxycholate reduces hepatotoxicity of bile salts in primary human hepatocytes.Q50878460
Ursodeoxycholic acid for treatment of primary sclerosing cholangitis: a placebo-controlled trialQ68019501
Ursodeoxycholic acid in primary biliary cirrhosis: results of a controlled double-blind trialQ69357047
Tauroursodeoxycholic acid activates protein kinase C in isolated rat hepatocytesQ71035961
Ursodeoxycholic acid in the treatment of primary biliary cirrhosisQ72401649
Effect of ursodeoxycholic acid on liver and bile duct disease in primary sclerosing cholangitis. A 3-year pilot study with a placebo-controlled study periodQ72503309
Ursodeoxycholate protects oxidative mitochondrial metabolism from bile acid toxicity: dose-response study in isolated rat liver mitochondriaQ72862935
P433issue1
P921main subjectapoptotic processQ14599311
P304page(s)99-106
P577publication date1998-01-01
P1433published inJournal of HepatologyQ15724402
P1476titleEffect of tauroursodeoxycholic acid on bile-acid-induced apoptosis and cytolysis in rat hepatocytes
P478volume28

Reverse relations

cites work (P2860)
Q37403072Apoptosis and necrosis in the liver
Q38694174Application of Tauroursodeoxycholic Acid for Treatment of Neurological and Non-neurological Diseases: Is There a Potential for Treating Traumatic Brain Injury?
Q24653969Bile acids: regulation of apoptosis by ursodeoxycholic acid
Q34170354Cell death at the millennium. Implications for liver diseases
Q62918400Comparison of the effects of bile acids on cell viability and DNA synthesis by rat hepatocytes in primary culture
Q44437820Dexamethasone and ursodeoxycholic acid protect against the arrhythmogenic effect of taurocholate in an in vitro study of rat cardiomyocytes
Q57107773Dexamethasone counteracts hepatic inflammation and oxidative stress in cholestatic rats via CAR activation
Q36495172Drug insight: Mechanisms and sites of action of ursodeoxycholic acid in cholestasis
Q35010904Effect of ZVAD-fmk on hepatocyte apoptosis after bile duct ligation in rat.
Q35687185Effect of bile duct ligation on bile acid composition in mouse serum and liver
Q51226271Effect of colitis and ileoanal pouch on biliary enrichment of ursodeoxycholic acid in primary sclerosing cholangitis.
Q45045457Effect of high-dose ursodeoxycholic acid on its biliary enrichment in primary sclerosing cholangitis
Q32142506Effects of bile salts on cholestan-3beta,5alpha,6beta-triol-induced apoptosis in dog gallbladder epithelial cells.
Q36173755GRP78 rescues the ABCG5 ABCG8 sterol transporter in db/db mice
Q50517174Hepatocyte apoptosis after bile duct ligation in the mouse involves Fas.
Q53493187Investigation of vitamin B₆ inadequacy, induced by exposure to the anti-B₆ factor 1-amino D-proline, on plasma lipophilic metabolites of rats: a metabolomics approach.
Q77598674Is ursodeoxycholate an antiapoptotic drug?
Q33591454Mechanism of hepatoprotective action of bile salts in liver disease
Q35734498Mechanisms of action and therapeutic efficacy of ursodeoxycholic acid in cholestatic liver disease
Q34170455Mechanisms of cholestasis
Q81724957Medical treatment of primary biliary cirrhosis and primary sclerosing cholangitis
Q33182216Micronuclei induction, cell cycle delay and apoptosis as markers of cellular stress caused by ursodeoxycholic acid in human lymphocytes.
Q36285749Novel insight into mechanisms of cholestatic liver injury
Q28274830Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling
Q41566502Strong activation of bile acid-sensitive ion channel (BASIC) by ursodeoxycholic acid
Q42924910Tauroursodeoxycholate counteracts hepatocellular lysis induced by tensioactive bile salts by preventing plasma membrane-micelle transition
Q34035789Tauroursodeoxycholic acid (TUDCA) protects photoreceptors from cell death after experimental retinal detachment
Q41672064Tauroursodeoxycholic acid attenuates endoplasmic reticulum stress and protects the liver from chronic intermittent hypoxia induced injury
Q35022852Tauroursodeoxycholic acid reduces apoptosis and protects against neurological injury after acute hemorrhagic stroke in rats
Q34075502Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease.
Q35760816Toll-like receptors 2 and 4 are differentially involved in Fas dependent apoptosis in Peyer's patch and the liver at an early stage after bile duct ligation in mice
Q46097462Transport of fluorescent bile acids by the isolated perfused rat liver: kinetics, sequestration, and mobilization
Q33866782Ursodeoxycholic acid treatment of vanishing bile duct syndromes
Q38965833Ursodeoxycholyl lysophosphatidylethanolamide inhibits cholestasis- and hypoxia-induced apoptosis by upregulating antiapoptosis proteins.
Q46508648Z-LLY-FMK can attenuate hepatocyte apoptosis after bile duct ligation in rat.
Q83868802[Liver apoptosis]

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