review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1016/S0955-0674(98)80008-2 |
P698 | PubMed publication ID | 9640533 |
P50 | author | Leonard P. Guarente | Q6525606 |
P2093 | author name string | R A Marciniak | |
F B Johnson | |||
P2860 | cites work | hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization | Q24310670 |
Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT | Q24313396 | ||
Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2 | Q24317670 | ||
Control of telomere length by the human telomeric protein TRF1 | Q24320111 | ||
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a | Q24324559 | ||
Extension of life-span by introduction of telomerase into normal human cells | Q24336088 | ||
A biomarker that identifies senescent human cells in culture and in aging skin in vivo | Q24562644 | ||
Specific Association of Human Telomerase Activity with Immortal Cells and Cancer | Q27860801 | ||
Constancy of ribosomal RNA genes during aging of mouse heart cells and during serial passage of WI-38 cells. | Q54788706 | ||
Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells | Q57250868 | ||
Human homologues of yeast helicase | Q59094515 | ||
Reexpression of the retinoblastoma protein in tumor cells induces senescence and telomerase inhibition | Q63446341 | ||
Loss of hybridizable ribosomal DNA from human post-mitotic tissues during aging: I. Age-dependent loss in human myocardium | Q66986632 | ||
Similar, but not identical, modulation of expression of extracellular matrix components during in vitro and in vivo aging of human skin fibroblasts | Q67590227 | ||
In vivo loss of telomeric repeats with age in humans | Q68048615 | ||
A subthreshold level of DNA topoisomerases leads to the excision of yeast rDNA as extrachromosomal rings | Q69351023 | ||
Loss of transcriptional silencing causes sterility in old mother cells of S. cerevisiae | Q70993045 | ||
Telomerase activity concentrates in the mitotically active segments of human hair follicles | Q71937963 | ||
Redistribution of silencing proteins from telomeres to the nucleolus is associated with extension of life span in S. cerevisiae. | Q27931333 | ||
A protein-counting mechanism for telomere length regulation in yeast. | Q27932745 | ||
Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants | Q27933022 | ||
Mitotic recombination in the rDNA of S. cerevisiae is suppressed by the combined action of DNA topoisomerases I and II. | Q27933954 | ||
Sgs1: a eukaryotic homolog of E. coli RecQ that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation | Q27939683 | ||
The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase | Q28170377 | ||
Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas | Q28258624 | ||
A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon | Q28639770 | ||
Mutation in the silencing gene S/R4 can delay aging in S. cerevisiae | Q29397443 | ||
Telomeres shorten during ageing of human fibroblasts | Q29547357 | ||
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA | Q29615386 | ||
Telomerase catalytic subunit homologs from fission yeast and human | Q29615387 | ||
Extrachromosomal rDNA circles--a cause of aging in yeast | Q29618308 | ||
Telomerase activity: a biomarker of cell proliferation, not malignant transformation | Q33719153 | ||
In vivo telomere dynamics of human hematopoietic stem cells | Q33726870 | ||
Telomere length and replicative aging in human vascular tissues | Q33763501 | ||
Telomerase activity in normal and malignant hematopoietic cells | Q33883794 | ||
ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase. | Q33887607 | ||
The telomere hypothesis of cellular aging | Q33973605 | ||
Extrachromosomal circular DNAs and genomic sequence plasticity in eukaryotic cells | Q34134591 | ||
Telomerase activity in the regenerative basal layer of the epidermis inhuman skin and in immortal and carcinoma-derived skin keratinocytes | Q34387542 | ||
Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts | Q35927191 | ||
Telomere length constancy during aging of Saccharomyces cerevisiae | Q36163972 | ||
Regulated expression of telomerase activity in human T lymphocyte development and activation | Q36366852 | ||
Changes of telomere length cause reciprocal changes in the lifespan of mother cells in Saccharomyces cerevisiae | Q36574621 | ||
Telomere lengthening and telomerase activation during human B cell differentiation | Q36596432 | ||
Reversible cellular senescence: implications for immortalization of normal human diploid fibroblasts | Q36770102 | ||
Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types. | Q36885740 | ||
Decreased synthesis of nucleolar RNA in aging human cells in vitro | Q36897324 | ||
Heterogeneity in telomere length of human chromosomes. | Q39426746 | ||
Telomerase and cancer: revisiting the telomere hypothesis | Q41211805 | ||
Telomerase activity is induced by the stimulation to antigen receptor in human peripheral lymphocytes | Q41228429 | ||
Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow | Q42528725 | ||
Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts | Q42815554 | ||
Age-related increase in methylation of ribosomal genes and inactivation of chromosome-specific rRNA gene clusters in mouse | Q49015368 | ||
Loss of hybridizable ribosomal DNA from human post-mitotic tissues during aging: II. Age-dependent loss in human cerebral cortex — Hippocampal and somatosensory cortex comparison | Q52106096 | ||
A longitudinal study of human age-related ribosomal RNA gene activity as detected by silver-stained NORs. | Q52198007 | ||
Up-regulation of telomerase activity in human lymphocytes. | Q53448795 | ||
P433 | issue | 3 | |
P304 | page(s) | 332-338 | |
P577 | publication date | 1998-06-01 | |
P1433 | published in | Current Opinion in Cell Biology | Q13505682 |
P1476 | title | Telomeres, the nucleolus and aging | |
P478 | volume | 10 |