| P2093 | author name string | H Derendorf | |
| | D T Lowenthal | |
| | A Hämmerlein | |
| P2860 | cites work | Toxicity of nitrazepam in the elderly: a report from the Boston Collaborative Drug Surveillance Program | Q24547894 |
| | Increased sensitivity to nitrazepam in old age | Q24675366 |
| | Geographical/interracial differences in polymorphic drug oxidation. Current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19 | Q28270486 |
| | Nitroglycerin-induced severe hypotension and bradycardia in patients with acute myocardial infarction | Q28330159 |
| | Non-oliguric renal failure during treatment with mefenamic acid in elderly patients: a continuing problem | Q28362367 |
| | Prediction of creatinine clearance from serum creatinine | Q29615603 |
| | Kinetic study of serum penicillin concentrations after single doses of benzathine and benethamine penicillins in young and old people. | Q33657738 |
| | Effect of Age and High Blood Pressure on Barorefiex Sensitivity in Man | Q34228478 |
| | Effect of aging on plasma renin and aldosterone in normal man | Q34232695 |
| | Relationship between diazepam dose, plasma level, age, and central nervous system depression | Q34254726 |
| | The effects of age on the pharmacokinetics and pharmacodynamics of single oral doses of benazepril and enalapril | Q34345707 |
| | Factors affecting drug binding in plasma of elderly patients | Q34515177 |
| | The influence of age on the response to anticoagulants | Q34515988 |
| | Adult lean body mass declines with age: some longitudinal observations | Q71543853 |
| | Catalytic unit of adenylate cyclase: reduced activity in aged-human lymphocytes | Q71839975 |
| | Effect of age on intestinal absorption: implications for drug absorption in the elderly | Q72151628 |
| | Contractile and biochemical correlates of beta-adrenergic stimulation of the aged heart | Q72433029 |
| | Brain benzodiazepine receptor changes during ageing | Q72482180 |
| | Alterations in leukocyte beta-receptor affinity with aging. A potential explanation for altered beta-adrenergic sensitivity in the elderly | Q72574271 |
| | Estimation of glomerular filtration rate by serum creatinine and serum beta 2-microglobulin | Q72650603 |
| | The place of the calcium antagonist verapamil in antihypertensive therapy | Q72684799 |
| | Influence of age, renal disease, hypertension, diuretics, and calcium on the antidiuretic responses to suboptimal infusions of vasopressin | Q72783187 |
| | Effect of 'autonomic blockade' on cardiac beta-adrenergic chronotropic responsiveness in healthy young, healthy elderly and endurance-trained elderly subjects | Q72793711 |
| | Gastric Emptying Rate in the Elderly: Implications for Drug Therapy | Q72891378 |
| | Age and cytochrome P450-linked drug metabolism in humans: an analysis of 226 subjects with equal histopathologic conditions | Q73198585 |
| | THE EFFECT OF INCREASING AGE ON THE DISTRIBUTION OF PERIPHERAL BLOOD FLOW IN MAN | Q78273811 |
| | Anatomy of body water and electrolytes | Q79222460 |
| | Age differences in the water content of the body as related to basal oxygen consumption in males | Q79666551 |
| | Utilization of nonsteroidal antiinflammatory drugs | Q93568748 |
| | The effect of ageing on the hepatic clearance of propranolol | Q34517399 |
| | Diazepam tolerance: effect of age, regular sedation, and alcohol | Q34551342 |
| | Age changes in glomerular filtration rate, effective renal plasma flow, and tubular excretory capacity in adult males | Q35180019 |
| | PHARMACOLOGIC ASPECTS OF AGING: A SURVEY OF THE EFFECT OF INCREASING AGE ON DRUG ACTIVITY IN ADULTS | Q35427173 |
| | Changes in calcium's role as a messenger during aging in neuronal and nonneuronal cells | Q35656609 |
| | Reduced high-affinity alpha 1-adrenoceptors in liver of senescent rats: implications of assessment at various temperatures | Q35888378 |
| | Nitrates in the elderly. Pharmacological considerations | Q35953658 |
| | Geriatric Pharmacology: Basic and Clinical Considerations* | Q36213480 |
| | Clinical pharmacokinetics of anxiolytics and hypnotics in the elderly. Therapeutic considerations (Part I). | Q36539873 |
| | Peripheral mononuclear leucocyte beta adrenoceptors and non-specific bronchial responsiveness to methacholine in young and elderly normal subjects and asthmatic patients | Q36542381 |
| | Benign Prostatic Hyperplasia: Pathogenesis and Medical Therapy | Q36699637 |
| | Mechanisms of altered hormone-neurotransmitter action during aging: from receptors to calcium mobilization | Q37615502 |
| | Nitrate therapy in the elderly | Q37814717 |
| | Opioid peptides and aging | Q37877526 |
| | Altered pharmacokinetics in the elderly. | Q37919206 |
| | Altered pharmacodynamics in the elderly | Q37919209 |
| | Understanding digoxin use in the elderly patient | Q38005547 |
| | Adverse drug reactions. An overview of special considerations in the management of the elderly patient | Q38031400 |
| | Calcium antagonists in the treatment of hypertension and angina pectoris in the elderly | Q38206444 |
| | Benzodiazepines of long and short elimination half-life and the risk of hip fracture | Q38367453 |
| | Tissue distribution of radioactivity after injection of [14C]nitrazepam in young and old rats | Q39196976 |
| | Reduced β-adrenoceptor sensitivity in the elderly | Q39256290 |
| | Digitalis. An update of clinical pharmacokinetics, therapeutic monitoring techniques and treatment recommendations | Q39533742 |
| | Orthostatic hypotension. II. Clinical diagnosis, testing, and treatment | Q39554757 |
| | Pharmacokinetic Consequences of Aging | Q39624005 |
| | Aging and drug disposition: an update | Q39830674 |
| | The aging gastrointestinal tract | Q39981763 |
| | Drug therapy in the elderly | Q40077731 |
| | Age-related alterations in the cardiovascular response to adrenergic mediated stress. | Q40083324 |
| | Changes in the mechanisms of hormone and neurotransmitter action during aging: Current status of the role of receptor and post-receptor alterations. A review | Q40089419 |
| | Disease-induced changes in the plasma binding of basic drugs | Q40098103 |
| | Alpha 1 -acid glycoprotein and binding of basic drugs | Q40170973 |
| | Orthostatic hypotension. I. Functional and neurogenic causes | Q40174375 |
| | Ageing, late-onset asthma and the beta-adrenoceptor | Q40695753 |
| | The use of intramuscular cefoperazone versus intramuscular ceftriaxone in patients with nursing home-acquired pneumonia | Q40711506 |
| | Pharmacokinetic changes in the elderly. Do they contribute to drug abuse and dependence? | Q40920809 |
| | Renal impairment associated with non-steroidal anti-inflammatory drugs | Q41159227 |
| | Effect of aging and cigarette smoking on antipyrine and indocyanine green elimination | Q41617487 |
| | Effects of age and cigarette smoking on propranolol disposition | Q41617556 |
| | Age-related changes in adenosine and beta-adrenoceptor responsiveness of vascular smooth muscle in man | Q41811120 |
| | Age as a determinant of sensitivity to warfarin | Q41946702 |
| | Isoproterenol Responsiveness and Myocardial -Adrenergic Receptors in Young and Old Rats | Q42451880 |
| | Impaired enzyme induction by rifampicin in the elderly | Q42531926 |
| | Age-related changes in the pharmacokinetics and pharmacodynamics of nifedipine | Q43229081 |
| | Factors influencing the responses to calcium antagonists in elderly patients with hypertension and ischaemic heart disease | Q43501430 |
| | The Effect of Age on Creatinine Clearance in Men: A Cross-sectional and Longitudinal Study | Q44464567 |
| | Age as a determinant of renal sodium conservation in normal man | Q44886120 |
| | Drug-induced illness as a cause for admission to a community hospital | Q44963457 |
| | Aging effects on stereoselective pharmacokinetics and pharmacodynamics of verapamil. | Q46058929 |
| | The effects of age and race on nitrendipine pharmacokinetics and pharmacodynamics. | Q46725646 |
| | Effect of Age and Sex on Human Drug Metabolism | Q50348052 |
| | The effect of aging on the pharmacokinetics and pharmacodynamics of prazosin. | Q51583793 |
| | Effect of age on the pharmacokinetics and sedative of flunitrazepam | Q51866187 |
| | Diazepam disposition determinants. | Q51877437 |
| | Brain cholinergic dysfunction and memory in aged rats | Q52105729 |
| | Decreased receptor activation with age. Can it be explained by desensitization? | Q52121027 |
| | Adverse drug reactions associated with global cognitive impairment in elderly persons. | Q53190031 |
| | Age-related decrease in cardiac and peripheral vascular responsiveness to isoprenaline: studies in normal subjects. | Q54535999 |
| | Creatinine clearance in renal disease. A reappraisal | Q55436059 |
| | Drug therapy | Q58071379 |
| | Plasma noradrenaline increases with age | Q59052463 |
| | Therapeutic Drug Monitoring in the Elderly | Q61820995 |
| | Systemic activity of orally administered L-dopa in the elderly Parkinson patient | Q64813435 |
| | The influence of age on the renal response to water deprivation in man | Q67780434 |
| | Perspectives on geriatric pharmacotherapy | Q67928102 |
| | The effect of age on serum albumin in healthy males: report from the Normative Aging Study | Q68250200 |
| | Effects of age and gender on in vitro properties of human liver microsomal monooxygenases | Q68362245 |
| | Nonsteroidal anti-inflammatory drugs | Q68506534 |
| | Comparison of age-related changes in prostaglandin E1 and beta-adrenergic responsiveness of vascular smooth muscle in adult males | Q69324975 |
| | Aging: ouabain-sensitive 86Rb+ uptake rate and responsiveness to digoxin in rat left atrial muscle | Q69326458 |
| | Imipramine and desipramine disposition in the elderly | Q70045130 |
| | Decline in beta adrenergic receptor-mediated vascular relaxation with aging in man | Q70158177 |
| | Aging and drug disposition--pharmacodynamics | Q70237605 |
| | Acetaminophen kinetics in the elderly | Q70271808 |
| | Age-related failure of volume-pressure-mediated vasopressin release | Q70273761 |
| | Effects of sulindac and ibuprofen in patients with chronic glomerular disease. Evidence for the dependence of renal function on prostacyclin | Q70309983 |
| | Pharmacokinetics of metoprolol in healthy, elderly, non-smoking individuals after a single dose and two weeks of treatment | Q70672025 |
| | Effect of aging on atenolol pharmacokinetics and pharmacodynamics | Q70789836 |
| | Baroreflex function in elderly hypertensives | Q71040551 |
| | Disposition of Antipyrine and Phenytoin Correlated with Age and Liver Volume in Man | Q71082674 |
| | Drug use in the United States in 1981 | Q71278366 |
| | The pharmacokinetics of cefuroxime in the elderly | Q71363915 |
| P433 | issue | 1 | |
| P921 | main subject | pharmacokinetics | Q323936 |
| | pharmacodynamics | Q725307 |
| P304 | page(s) | 49-64 | |
| P577 | publication date | 1998-07-01 | |
| P1433 | published in | Clinical Pharmacokinetics | Q5133788 |
| P1476 | title | Pharmacokinetic and pharmacodynamic changes in the elderly. Clinical implications | |
| P478 | volume | 35 | |