Protein transport from the secretory to the endocytic pathway in mammalian cells

scientific article published on 01 August 1998

Protein transport from the secretory to the endocytic pathway in mammalian cells is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0167-4889(98)00057-3
P698PubMed publication ID9714803

P50authorRoland Le BorgneQ42720287
P2093author name stringB Hoflack
P2860cites workLigand binding specificities of the two mannose 6-phosphate receptorsQ71973552
The phosphorylation pattern of oligosaccharides in secreted procathepsin D is glycosylation site-specific and independent of the expression of mannose 6-phosphate receptorsQ71973580
Overexpression of TGN38/41 leads to mislocalisation of gamma-adaptinQ72180617
Mistargeting of lysosomal enzymes in M(r) 46,000 mannose 6-phosphate receptor-deficient mice is compensated by carbohydrate-specific endocytotic receptorsQ72715547
Comparative activity of ADP-ribosylation factor family members in the early steps of coated vesicle formation on rat liver Golgi membranesQ73039034
Systematic mutational analysis of the cation-independent mannose 6-phosphate/insulin-like growth factor II receptor cytoplasmic domain. An acidic cluster containing a key aspartate is important for function in lysosomal enzyme sortingQ73119350
The 46-kDa mannose 6-phosphate receptor contains multiple binding sites for clathrin adaptorsQ73555548
Roles for mannose-6-phosphate receptors in lysosomal enzyme sorting, IGF-II binding and clathrin-coat assemblyQ75292522
AP-3: an adaptor-like protein complex with ubiquitous expressionQ24315945
Regulatory interactions in the recognition of endocytic sorting signals by AP-2 complexesQ24336247
Two independent targeting signals in the cytoplasmic domain determine trans-Golgi network localization and endosomal trafficking of the proprotein convertase furinQ24568252
The targeting of Lamp1 to lysosomes is dependent on the spacing of its cytoplasmic tail tyrosine sorting motif relative to the membraneQ24651864
Nef-mediated clathrin-coated pit formationQ24678715
Mannose 6-phosphate receptors regulate the formation of clathrin-coated vesicles in the TGNQ24678853
Intracellular movement of two mannose 6-phosphate receptors: return to the Golgi apparatusQ24679792
A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chainsQ27913878
Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sortingQ27940116
ADP-Ribosylation factor is a subunit of the coat of Golgi-derived COP-coated vesicles: A novel role for a GTP-binding proteinQ28248936
Interaction of tyrosine-based sorting signals with clathrin-associated proteinsQ28290076
Arf proteins: the membrane traffic police?Q28302542
The MHC class II molecule H2-M is targeted to an endosomal compartment by a tyrosine-based targeting motifQ28585954
ADP-ribosylation factor, a small GTP-binding protein, is required for binding of the coatomer protein beta-COP to Golgi membranesQ28609784
Targeting of membrane proteins to endosomes and lysosomesQ28612146
MHC class II-associated invariant chain contains a sorting signal for endosomal compartmentsQ28612553
Expression of major histocompatibility complex class II molecules in HeLa cells promotes the recruitment of AP-1 Golgi-specific assembly proteins on Golgi membranesQ28613132
Endocytosis and molecular sortingQ29616706
The biogenesis of lysosomesQ29617860
Clathrin-coated vesicle formation and protein sorting: an integrated processQ29619729
Protein sorting by transport vesiclesQ29619990
Signal-dependent membrane protein trafficking in the endocytic pathwayQ29622948
Targeted disruption of the M(r) 46,000 mannose 6-phosphate receptor gene in mice results in misrouting of lysosomal proteinsQ34065410
Structure and function of the mannose 6-phosphate/insulinlike growth factor II receptorsQ34236758
Phospholipase D is present on Golgi-enriched membranes and its activation by ADP ribosylation factor is sensitive to brefeldin AQ34277362
Assembly, transport, and function of MHC class II moleculesQ34328789
Targeting of glycoprotein I (gE) of varicella-zoster virus to the trans-Golgi network by an AYRV sequence and an acidic amino acid-rich patch in the cytosolic domain of the molecule.Q35869359
Accumulation of membrane glycoproteins in lysosomes requires a tyrosine residue at a particular position in the cytoplasmic tailQ36223847
Phosphorylation of the cation-independent mannose 6-phosphate receptor is closely associated with its exit from the trans-Golgi network.Q36232193
Localization of TGN38 to the trans-Golgi network: involvement of a cytoplasmic tyrosine-containing sequenceQ36233082
Cytoplasmic determinants involved in direct lysosomal sorting, endocytosis, and basolateral targeting of rat lgp120 (lamp-I) in MDCK cells.Q36235231
Endocytosis of activated receptors and clathrin-coated pit formation: deciphering the chicken or egg relationshipQ36236611
Evidence that phospholipase D mediates ADP ribosylation factor-dependent formation of Golgi coated vesiclesQ36236974
The production of post-Golgi vesicles requires a protein kinase C-like molecule, but not its phosphorylating activityQ36237532
Protein targeting by tyrosine- and di-leucine-based signals: evidence for distinct saturable componentsQ36237576
Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cellsQ36382633
A lysosomal targeting signal in the cytoplasmic tail of the beta chain directs HLA-DM to MHC class II compartments.Q36382769
Biochemical dissection of AP-1 recruitment onto Golgi membranes.Q36383269
Transport of the lysosomal membrane glycoprotein lgp120 (lgp-A) to lysosomes does not require appearance on the plasma membraneQ36531261
100-kD proteins of Golgi- and trans-Golgi network-associated coated vesicles have related but distinct membrane binding propertiesQ36531520
Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiaeQ36775602
Lysosomal storage diseasesQ37285237
Identification and characterization of cells deficient in the mannose 6-phosphate receptor: evidence for an alternate pathway for lysosomal enzyme targetingQ37603016
A di-leucine motif mediates endocytosis and basolateral sorting of macrophage IgG Fc receptors in MDCK cells.Q37633898
A casein kinase II phosphorylation site in the cytoplasmic domain of the cation-dependent mannose 6-phosphate receptor determines the high affinity interaction of the AP-1 Golgi assembly proteins with membranesQ38362519
Varicella and herpes zoster. Changing concepts of the natural history, control, and importance of a not-so-benign virusQ40108192
Lonely MHC molecules seeking immunogenic peptides for meaningful relationships.Q40380611
Mechanisms of cell polarity: sorting and transport in epithelial cellsQ40647437
Antigen processing and intracellular traffic of antigens and MHC moleculesQ40788793
ARF signaling: a potential role for phospholipase D in membrane trafficQ40790966
Targeted disruption of the mouse cation-dependent mannose 6-phosphate receptor results in partial missorting of multiple lysosomal enzymes.Q40874604
Insulin-like growth factor II/cation-independent mannose 6-phosphate receptor and lysosomal enzyme recognitionQ41011112
Receptor-mediated protein sorting to the vacuole in yeast: roles for a protein kinase, a lipid kinase and GTP-binding proteinsQ41020937
Major histocompatibility complex class II compartments in human and mouse B lymphoblasts represent conventional endocytic compartmentsQ41082969
The role of ADP-ribosylation factor and phospholipase D in adaptor recruitmentQ41090845
Developmental regulation of MHC class II transport in mouse dendritic cells.Q41093187
Interaction of furin in immature secretory granules from neuroendocrine cells with the AP-1 adaptor complex is modulated by casein kinase II phosphorylationQ41093806
The biogenesis of the MHC class II compartment in human I-cell disease B lymphoblastsQ41225461
Targeting of a lysosomal membrane protein: a tyrosine-containing endocytosis signal in the cytoplasmic tail of lysosomal acid phosphatase is necessary and sufficient for targeting to lysosomes.Q41229177
Cysteine34 of the cytoplasmic tail of the cation-dependent mannose 6-phosphate receptor is reversibly palmitoylated and required for normal trafficking and lysosomal enzyme sortingQ41233270
The AP-1 adaptor complex binds to immature secretory granules from PC12 cells, and is regulated by ADP-ribosylation factorQ41233302
Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2/Mpr geneQ41415190
Possible pathways for lysosomal enzyme deliveryQ41494255
Clathrin-coated vesicular transport of secretory proteins during the formation of ACTH-containing secretory granules in AtT20 cellsQ41508036
ADP-ribosylation factor, a small GTP-dependent regulatory protein, stimulates phospholipase D activityQ41508317
Mannose-6-phosphate receptors for lysosomal enzymes cycle between the Golgi complex and endosomesQ41510082
Mannose 6-phosphate-independent targeting of lysosomal enzymes in I-cell disease B lymphoblastsQ41522156
Differences in the endosomal distributions of the two mannose 6-phosphate receptorsQ41551657
The trans-Golgi network: a late secretory sorting stationQ41566653
Linking cargo to vesicle formation: receptor tail interactions with coat proteins.Q41566699
The cytoplasmic tail of the mannose 6-phosphate/insulin-like growth factor-II receptor has two signals for lysosomal enzyme sorting in the GolgiQ41600770
Recruitment of coat proteins onto Golgi membranes in intact and permeabilized cells: effects of brefeldin A and G protein activatorsQ41629883
Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane trafficQ41659144
Brefeldin A causes a microtubule-mediated fusion of the trans-Golgi network and early endosomesQ41659646
Wortmannin causes mistargeting of procathepsin D. evidence for the involvement of a phosphatidylinositol 3-kinase in vesicular transport to lysosomesQ41680092
A novel class of clathrin-coated vesicles budding from endosomesQ41811118
The TGN38 glycoprotein contains two non-overlapping signals that mediate localization to the trans-Golgi networkQ41907333
The roles of multiple pathways in regulating bombesin-stimulated phospholipase D activity in Swiss 3T3 fibroblastsQ42087694
Re-expression of the mannose 6-phosphate receptors in receptor-deficient fibroblasts. Complementary function of the two mannose 6-phosphate receptors in lysosomal enzyme targetingQ42811862
Ras mediates the activation of phospholipase D by v-SrcQ42829231
Regulation and function of the CD3gamma DxxxLL motif: a binding site for adaptor protein-1 and adaptor protein-2 in vitro.Q42831149
A role for the cytoplasmic domain in transferrin receptor sorting and coated pit formation during endocytosisQ43861571
Transferrin receptors promote the formation of clathrin latticesQ44496269
Intracellular transport of class II MHC molecules directed by invariant chain.Q45941447
The binding of AP-1 clathrin adaptor particles to Golgi membranes requires ADP-ribosylation factor, a small GTP-binding proteinQ48268447
Regulation of phospholipase D by protein kinase C is synergistic with ADP-ribosylation factor and independent of protein kinase activityQ49112664
A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting.Q52241373
The Two Mannose 6-Phosphate Receptors Transport Distinct Complements of Lysosomal ProteinsQ52508397
Regulated formation of Golgi secretory vesicles containing Alzheimer beta-amyloid precursor protein.Q53200160
Mutations in the cytoplasmic domain of the 275 kd mannose 6-phosphate receptor differentially alter lysosomal enzyme sorting and endocytosisQ69348661
Cation-independent mannose 6-phosphate receptor contains covalently bound fatty acidQ69848201
Brefeldin A, a drug that blocks secretion, prevents the assembly of non-clathrin-coated buds on Golgi cisternaeQ70118298
Varicella and herpes zoster. Changing concepts of the natural history, control, and importance of a not-so-benign virusQ70171440
Mannose 6-phosphate receptors and ADP-ribosylation factors cooperate for high affinity interaction of the AP-1 Golgi assembly proteins with membranesQ70915222
Membranes and sortingQ71497055
Structural determinants of interaction of tyrosine-based sorting signals with the adaptor medium chainsQ71763363
P433issue1-2
P407language of work or nameEnglishQ1860
P304page(s)195-209
P577publication date1998-08-01
P1433published inBiochimica et Biophysica ActaQ864239
P1476titleProtein transport from the secretory to the endocytic pathway in mammalian cells
P478volume1404

Reverse relations

cites work (P2860)
Q24296699A role of Rab29 in the integrity of the trans-Golgi network and retrograde trafficking of mannose-6-phosphate receptor
Q28505233ABC1 promotes engulfment of apoptotic cells and transbilayer redistribution of phosphatidylserine
Q96950906ACTL6A suppresses p21Cip1 expression to enhance the epidermal squamous cell carcinoma phenotype
Q42817051Absence of metabolic cross-correction in Tay-Sachs cells: implications for gene therapy
Q44282963Arf regulates interaction of GGA with mannose-6-phosphate receptor
Q42500097Biogenesis of insulin-responsive GLUT4 vesicles is independent of brefeldin A-sensitive trafficking
Q34157474Bioremediation meets biomedicine: therapeutic translation of microbial catabolism to the lysosome
Q37607826Carbohydrate recognition by the mannose-6-phosphate receptors
Q24318397Characterization of RNASET2, the first human member of the Rh/T2/S family of glycoproteins
Q28186267Characterization of periphilin, a widespread, highly insoluble nuclear protein and potential constituent of the keratinocyte cornified envelope
Q24293118Consequences of C-terminal domains and N-terminal signal peptide deletions on LEKTI secretion, stability, and subcellular distribution
Q34156628Control of MHC class I traffic from the endoplasmic reticulum by cellular chaperones and viral anti-chaperones
Q57269823Direct and GTP-dependent Interaction of ADP-ribosylation Factor 1 with Clathrin Adaptor Protein AP-1 on Immature Secretory Granules
Q50736422Efficient sorting of TNF-alpha to rodent mast cell granules is dependent on N-linked glycosylation
Q40825187Endocytosis of uncleaved tumor necrosis factor-alpha in macrophages
Q24673739Enthoprotin: a novel clathrin-associated protein identified through subcellular proteomics
Q44624370Enzyme replacement therapy in the mouse model of Pompe disease
Q27938814Exomer: A coat complex for transport of select membrane proteins from the trans-Golgi network to the plasma membrane in yeast
Q40824721Expression and properties of Rab7 in endosome function
Q34594223Genetic analyses of adaptin function from yeast to mammals.
Q24291292Golgi-localizing, gamma-adaptin ear homology domain, ADP-ribosylation factor-binding (GGA) proteins interact with acidic dileucine sequences within the cytoplasmic domains of sorting receptors through their Vps27p/Hrs/STAM (VHS) domains
Q36961207Heterotrimeric G proteins and the single-transmembrane domain IGF-II/M6P receptor: functional interaction and relevance to cell signaling
Q44770049Identification of multivesicular bodies as prevacuolar compartments in Nicotiana tabacum BY-2 cells.
Q34064287Impact of genetic variation in SORCS1 on memory retention
Q37403999Insulin-like growth factor-2/mannose-6 phosphate receptors.
Q34348694Intracellular cycling of lysosomal enzyme receptors: cytoplasmic tails' tales
Q35131675Intracellular sorting and transport of proteins
Q28610116Lectins and traffic in the secretory pathway
Q46233609Liver sinusoidal endothelial cells depend on mannose receptor-mediated recruitment of lysosomal enzymes for normal degradation capacity.
Q44175842Localization of the carbohydrate recognition sites of the insulin-like growth factor II/mannose 6-phosphate receptor to domains 3 and 9 of the extracytoplasmic region
Q42157567Lysosome-associated protein transmembrane 4 alpha (LAPTM4 alpha) requires two tandemly arranged tyrosine-based signals for sorting to lysosomes
Q28213265Mannose 6-phosphate receptors: new twists in the tale
Q35039010Myelin biogenesis: vesicle transport in oligodendrocytes
Q33745455New animal lectin structures
Q40941473Overexpression of proteins containing tyrosine- or leucine-based sorting signals affects transferrin receptor trafficking
Q40883823Phosphorylation of class I MHC molecules in the absence of phorbol esters is an intracellular event and may be characteristic of trafficking molecules
Q36650539Plant prevacuolar/endosomal compartments
Q35157544Protein trafficking in Giardia lamblia
Q34158273Regulated expression and intracellular localization of cystatin F in human U937 cells
Q40483409Replacing acid alpha-glucosidase in Pompe disease: recombinant and transgenic enzymes are equipotent, but neither completely clears glycogen from type II muscle fibers.
Q37398071RhoB plays an essential role in CXCR2 sorting decisions
Q30164362Role of amphiphysin II in somatostatin receptor trafficking in neuroendocrine cells
Q34914826SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk
Q44238568Sorting of encystation-specific cysteine protease to lysosome-like peripheral vacuoles in Giardia lamblia requires a conserved tyrosine-based motif.
Q28619355Sorting of furin at the trans-Golgi network. Interaction of the cytoplasmic tail sorting signals with AP-1 Golgi-specific assembly proteins
Q36610341Sorting through the cell biology of Alzheimer's disease: intracellular pathways to pathogenesis
Q28206128Specific regulation of the adaptor protein complex AP-3 by the Arf GAP AGAP1
Q33944782Sphingolipid transport in eukaryotic cells.
Q37214274Strategies for carbohydrate recognition by the mannose 6-phosphate receptors
Q27649848Structural Insights into the Mechanism of pH-dependent Ligand Binding and Release by the Cation-dependent Mannose 6-Phosphate Receptor
Q36897806The cytoplasmic domain of proEGF negatively regulates motility and elastinolytic activity in thyroid carcinoma cells.
Q34067421The delta subunit of AP-3 is required for efficient transport of VSV-G from the trans-Golgi network to the cell surface
Q40734998The p55 tumour necrosis factor receptor TNFR1 contains a trans-Golgi network localization signal in the C-terminal region of its cytoplasmic tail.
Q39902669Trafficking of TrkA-green fluorescent protein chimerae during nerve growth factor-induced differentiation
Q34350937Trans-Golgi network sorting
Q36639665Transmembrane helix predictions revisited
Q24645802Transport of mannose-6-phosphate receptors from the trans-Golgi network to endosomes requires Rab31
Q39455769Two conserved amino acid motifs mediate protein targeting to the micronemes of the apicomplexan parasite Toxoplasma gondii
Q28204893Unraveling the molecular pathogenesis of free sialic acid storage disorders: altered targeting of mutant sialin
Q33640956Use of genetic variation as biomarkers for Alzheimer's disease
Q34013606Use of genetic variation as biomarkers for mild cognitive impairment and progression of mild cognitive impairment to dementia
Q78132396Vacuolar storage proteins and the putative vacuolar sorting receptor BP-80 exit the golgi apparatus of developing pea cotyledons in different transport vesicles
Q42944678Vacuolar storage proteins are sorted in the cis-cisternae of the pea cotyledon Golgi apparatus
Q30656030beta2-adaptin is constitutively de-phosphorylated by serine/threonine protein phosphatase PP2A and phosphorylated by a staurosporine-sensitive kinase

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