Regulation of cell cycle and productivity in NS0 cells by the over-expression of p21CIP1

scientific article published on 01 January 2002

Regulation of cell cycle and productivity in NS0 cells by the over-expression of p21CIP1 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/BIT.10112
P698PubMed publication ID11745168

P2093author name stringMohamed Al-Rubeai
John Shuttleworth
Shikiko Watanabe
P2860cites workCloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signalsQ24314293
CDK inhibitors: positive and negative regulators of G1-phase progressionQ27860983
WAF1, a potential mediator of p53 tumor suppressionQ27861121
p21 is a universal inhibitor of cyclin kinasesQ28257305
Principles of CDK regulationQ29547820
Expression and activity of p40MO15, the catalytic subunit of cdk-activating kinase, during Xenopus oogenesis and embryogenesisQ34444724
Inhibition of cyclin-dependent kinases by p21Q34447738
Regulation of lymphocyte survival by the bcl-2 gene familyQ40444925
Bcl-2 mediated suppression of apoptosis in myeloma NS0 cultures.Q40879562
pTRIDENT, a novel vector family for tricistronic gene expression in mammalian cellsQ40963510
Controlled proliferation by multigene metabolic engineering enhances the productivity of Chinese hamster ovary cellsQ41042013
p21WAF1 induces permanent growth arrest and enhances differentiation, but does not alter apoptosis in PC12 cellsQ41062964
Induction of growth arrest and cell death by overexpression of the cyclin-Cdk inhibitor p21 in hamster BHK21 cellsQ41064833
Super-CHO-A cell line capable of autocrine growth under fully defined protein-free conditionsQ41240981
Growth and interferon-gamma production in batch culture of CHO cellsQ41504941
Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit.Q41508377
Negative regulation of G1 in mammalian cells: inhibition of cyclin E-dependent kinase by TGF-beta.Q41559119
Effects of ammonia and lactate on hybridoma growth, metabolism, and antibody productionQ41639279
Process development for the production of recombinant antibodies using the glutamine synthetase (GS) systemQ41649450
Transient kinetics of hybridoma growth and monoclonal antibody production in serum-limited culturesQ44874266
A kinetic analysis of hybridoma growth and metabolism in batch and continuous suspension culture: effect of nutrient concentration, dilution rate, and pH.Q46776525
A novel cytostatic process enhances the productivity of Chinese hamster ovary cells.Q50627384
Cell death in bioreactors: a role for apoptosis.Q52692588
Mechanisms and kinetics of monoclonal antibody synthesis and secretion in synchronous and asynchronous hybridoma cell culturesQ67527606
Chinese hamster ovary cell growth and interferon production kinetics in stirred batch cultureQ67528226
Effect of temperature on hybridoma cell cycle and MAb productionQ81580137
Induction of apoptosis in nutrient-deprived cultures of hybridoma and myeloma cellsQ81632448
P433issue1
P304page(s)1-7
P577publication date2002-01-01
P1433published inBiotechnology and BioengineeringQ4915339
P1476titleRegulation of cell cycle and productivity in NS0 cells by the over-expression of p21CIP1
P478volume77

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cites work (P2860)
Q36255055Application of a reversible immortalization system for the generation of proliferation-controlled cell lines.
Q34762106Artificial mammalian gene regulation networks-novel approaches for gene therapy and bioengineering
Q39026298Dynamics of unfolded protein response in recombinant CHO cells
Q39880564Metabolic characterization of a hyper-productive state in an antibody producing NS0 myeloma cell line
Q30492978Proliferation control strategies to improve productivity and survival during CHO based production culture : A summary of recent methods employed and the effects of proliferation control in product secreting CHO cell lines
Q40414134Regulation of cell proliferation and apoptosis in CHO-K1 cells by the coexpression of c-Myc and Bcl-2.
Q50145945The Saccharomyces cerevisiae pheromone-response is a metabolically active stationary phase for bio-production
Q28652788Use of a small molecule cell cycle inhibitor to control cell growth and improve specific productivity and product quality of recombinant proteins in CHO cell cultures
Q37323557Using cell engineering and omic tools for the improvement of cell culture processes
Q42188081pH Condition in temperature shift cultivation enhances cell longevity and specific hMab productivity in CHO culture