| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1126/SCIENCE.282.5386.63 |
| P698 | PubMed publication ID | 9756477 |
| P2093 | author name string | C T Walsh | |
| C Khosla | |||
| D E Cane | |||
| P2860 | cites work | Expression of a functional fungal polyketide synthase in the bacterium Streptomyces coelicolor A3(2) | Q35591997 |
| P433 | issue | 5386 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 63-68 | |
| P577 | publication date | 1998-10-01 | |
| P1433 | published in | Science | Q192864 |
| P1476 | title | Harnessing the biosynthetic code: combinations, permutations, and mutations | |
| P478 | volume | 282 |
| Q37811894 | A comprehensive overview on genomically directed assembly of aromatic polyketides and macrolide lactones using fungal megasynthases. |
| Q43006481 | A mechanism-based fluorescence transfer assay for examining ketosynthase selectivity |
| Q35022566 | A novel class of gene controlling virulence in plant pathogenic ascomycete fungi |
| Q36021739 | A platform for the discovery of new macrolide antibiotics. |
| Q33237794 | A protein interaction surface in nonribosomal peptide synthesis mapped by combinatorial mutagenesis and selection |
| Q35951104 | A putative polyketide-synthesis protein XC5357 from Xanthomonas campestris: heterologous expression, crystallization and preliminary X-ray analysis |
| Q47370767 | A research proposal on the origin of life |
| Q36608373 | A synthetic recursive "+1" pathway for carbon chain elongation |
| Q35708610 | Accessing natural products by combinatorial biosynthesis |
| Q39070873 | Active site-directed proteomic probes for adenylation domains in nonribosomal peptide synthetases. |
| Q64897732 | Acyltransferases as Tools for Polyketide Synthase Engineering. |
| Q92882958 | Albicidin, a potent DNA gyrase inhibitor with clinical potential |
| Q59079485 | Alternative modular polyketide synthase expression controls macrolactone structure |
| Q44578590 | Aminoacyl adenylate substrate analogues for the inhibition of adenylation domains of nonribosomal peptide synthetases |
| Q33519058 | An engineered yeast efficiently secreting penicillin |
| Q38322555 | Analysis of engineered multifunctional peptide synthetases. Enzymatic characterization of surfactin synthetase domains in hybrid bimodular systems |
| Q30931188 | Antifungal compounds from cyanobacteria. |
| Q44499187 | Architectural self-construction in nature and chemical synthesis |
| Q33834986 | Atlas of nonribosomal peptide and polyketide biosynthetic pathways reveals common occurrence of nonmodular enzymes. |
| Q28828730 | Biochemical and Structural Basis for Controlling Chemical Modularity in Fungal Polyketide Biosynthesis |
| Q36096741 | Biochemical studies of the lagunamides, potent cytotoxic cyclic depsipeptides from the marine cyanobacterium Lyngbya majuscula. |
| Q40121669 | Biomedicinals from the phytosymbionts of marine invertebrates: a molecular approach |
| Q39923516 | Biomimetic catalysis of intermodular aminoacyl transfer |
| Q28217202 | Biomimetic synthesis and optimization of cyclic peptide antibiotics |
| Q43515349 | Biosynthesis of L-p-hydroxyphenylglycine, a non-proteinogenic amino acid constituent of peptide antibiotics |
| Q34010324 | Biosynthesis of polyketides in heterologous hosts |
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| Q30960118 | Biotechnological prospects from metagenomics |
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| Q89004889 | Broadened glycosylation patterning of heterologously produced erythromycin |
| Q37946335 | Carboxylases in natural and synthetic microbial pathways |
| Q34144604 | Catalysis at the intersection of biology, chemistry, and medicine |
| Q27640455 | Catalysis, specificity, and ACP docking site of Streptomyces coelicolor malonyl-CoA:ACP transacylase |
| Q33431528 | Chapter 10 using phosphopantetheinyl transferases for enzyme posttranslational activation, site specific protein labeling and identification of natural product biosynthetic gene clusters from bacterial genomes. |
| Q83677610 | Chapter 15. Plasmid-borne gene cluster assemblage and heterologous biosynthesis of nonribosomal peptides in Escherichia coli |
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| Q41032246 | Characterization of the Ketosynthase and Acyl Carrier Protein Domains at the LnmI Nonribosomal Peptide Synthetase-Polyketide Synthase Interface for Leinamycin Biosynthesis. |
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| Q34150464 | Combinatorial and computational challenges for biocatalyst design |
| Q35879503 | Combinatorial biosynthesis of RiPPs: docking with marine life |
| Q24557524 | Combinatorial biosynthesis of antitumor indolocarbazole compounds |
| Q30662200 | Combinatorial biosynthesis of polyketides and nonribosomal peptides |
| Q36328793 | Combinatorial biosynthesis of reduced polyketides |
| Q34722973 | Comparative analysis of the biosynthetic gene clusters and pathways for three structurally related antitumor antibiotics: bleomycin, tallysomycin, and zorbamycin |
| Q42378249 | Comparative analysis of the biosynthetic systems for fungal bicyclo[2.2.2]diazaoctane indole alkaloids: the (+)/(-)-notoamide, paraherquamide and malbrancheamide pathways |
| Q44400938 | Computational approach for prediction of domain organization and substrate specificity of modular polyketide synthases |
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| Q35750870 | Construction of hybrid peptide synthetases by module and domain fusions |
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| Q35659229 | Coupling Binding to Catalysis: Using Yeast Cell Surface Display to Select Enzymatic Activities |
| Q27663890 | Crystal Structures and Mutational Analyses of Acyl-CoA Carboxylase β Subunit of Streptomyces coelicolor , |
| Q27636992 | Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: Versatility from a unique substrate channel |
| Q27639955 | Crystal structure of the priming beta-ketosynthase from the R1128 polyketide biosynthetic pathway |
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| Q34029169 | Directed evolution: the 'rational' basis for 'irrational' design. |
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| Q34150445 | Enzymes for chemical synthesis |
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| Q37333806 | Evolution of multi-component anion relay chemistry (ARC): construction of architecturally complex natural and unnatural products |
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| Q33753331 | Expanding the fluorine chemistry of living systems using engineered polyketide synthase pathways. |
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| Q36729066 | Explorations of catalytic domains in non-ribosomal peptide synthetase enzymology |
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| Q34647692 | Genetics and assembly line enzymology of siderophore biosynthesis in bacteria |
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| Q35763602 | Genome mining for natural product biosynthetic gene clusters in the Subsection V cyanobacteria |
| Q38429580 | Genome mining: Prediction of lipopeptides and polyketides from Bacillus and related Firmicutes |
| Q42178119 | Genome-based studies of marine microorganisms to maximize the diversity of natural products discovery for medical treatments |
| Q41011831 | Heterologous expression of diverse propionyl-CoA carboxylases affects polyketide production in Escherichia coli. |
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| Q33712368 | Hybrid enzymes |
| Q37557394 | Hyper-inducible expression system for streptomycetes |
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| Q39680877 | Identification and localization of the gene cluster encoding biosynthesis of the antitumor macrolactam leinamycin in Streptomyces atroolivaceus S-140. |
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