ERK pathway mediates the activation of Cdk2 in IGF-1-induced proliferation of human osteosarcoma MG-63 cells

scientific article published on 01 April 1999

ERK pathway mediates the activation of Cdk2 in IGF-1-induced proliferation of human osteosarcoma MG-63 cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1359/JBMR.1999.14.4.528
P698PubMed publication ID10234573

P2093author name stringS Kumar
W Zhang
J C Lee
M Gowen
P2860cites workIsolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinaseQ24307836
Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1Q24309607
P433issue4
P304page(s)528-535
P577publication date1999-04-01
P1433published inJournal of Bone and Mineral ResearchQ15750941
P1476titleERK pathway mediates the activation of Cdk2 in IGF-1-induced proliferation of human osteosarcoma MG-63 cells
P478volume14

Reverse relations

cites work (P2860)
Q34869180A new approach for prediction of tumor sensitivity to targeted drugs based on functional data
Q45879706Change of p16(INK4a) and PCNA protein expression in myocardium after injection of hIGF-1 gene modified skeletal myoblasts into post-infarction rats
Q44550185Effects of combined treatment of insulin and human parathyroid hormone(1-34) on cancellous bone mass and structure in streptozotocin-induced diabetic rats
Q37217121IGF-I regulates tight-junction protein claudin-1 during differentiation of osteoblast-like MC3T3-E1 cells via a MAP-kinase pathway
Q40640880Immature human osteoblastic MG63 cells predominantly express a subtype 1-like CGRP receptor that inactivates extracellular signal response kinase by a cAMP-dependent mechanism
Q41035104Insulin-like growth factor I regulates G2/M progression through mammalian target of rapamycin signaling in oligodendrocyte progenitors.
Q40719474Mechanical strain and fluid movement both activate extracellular regulated kinase (ERK) in osteoblast-like cells but via different signaling pathways
Q83265745Mechanisms of drug combinations: interaction and network perspectives
Q40809278Mitogenic G(i) protein-MAP kinase signaling cascade in MC3T3-E1 osteogenic cells: activation by C-terminal pentapeptide of osteogenic growth peptide [OGP(10-14)] and attenuation of activation by cAMP.
Q37761069Nanoparticles: a promising modality in the treatment of sarcomas.
Q39181880Network-based identification of key proteins involved in apoptosis and cell cycle regulation.
Q37598645New insights into mineralogenic effects of vanadate
Q37135526New insights into purinergic receptor signaling in neuronal differentiation, neuroprotection, and brain disorders
Q74414282Osteoprotegerin ameliorates sciatic nerve crush induced bone loss
Q40714072Paracrine activation of extracellular signal-regulated kinase in a simple in vitro model of wounded osteoblasts
Q39616703Proliferative and mineralogenic effects of insulin, IGF-1, and vanadate in fish osteoblast-like cells
Q28573474Regulatory role of endogenous regucalcin in the enhancement of nuclear deoxyribonuleic acid synthesis with proliferation of cloned rat hepatoma cells (H4-II-E)
Q42452984Role of PTEN and Akt in the regulation of growth and apoptosis in human osteoblastic cells
Q28571001Role of endogenous regucalcin in nuclear regulation of regenerating rat liver: suppression of the enhanced ribonucleic acid synthesis activity
Q41887113STRAP regulates c-Jun ubiquitin-mediated proteolysis and cellular proliferation
Q77986088Suppressive role of endogenous regucalcin in the enhancement of deoxyribonucleic acid synthesis activity in the nucleus of regenerating rat liver
Q37047540Synergistic effect of low-dose cucurbitacin B and low-dose methotrexate for treatment of human osteosarcoma
Q51328396The lack of Raf-1 kinase feedback regulation enhances antiapoptosis in cancer cells.
Q42826872Transforming growth factor-beta-induced osteoblast elongation regulates osteoclastic bone resorption through a p38 mitogen-activated protein kinase- and matrix metalloproteinase-dependent pathway.

Search more.