The frequency of illegitimate V(D)J recombinase-mediated mutations in children treated with etoposide-containing antileukemic therapy

scientific article published on 01 November 1998

The frequency of illegitimate V(D)J recombinase-mediated mutations in children treated with etoposide-containing antileukemic therapy is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S1383-5718(98)00129-6
P698PubMed publication ID9804912

P2093author name stringM V Relling
R W Setzer
C H Pui
J T Sandlund
N M Hanley
J C Fuscoe
G W Knapp
P2860cites workQuantification of hprt gene deletions mediated by illegitimate V(D)J recombination in peripheral blood cells of humansQ48056177
Acute myelomonocytic leukemia with t(10;11)(p13;q23): heterogeneity of breakpoints at 11q23 and association with recombinase activation.Q51131209
Chromosomal translocations in human cancer.Q52512616
Quantification of t(14;18) in the lymphocytes of healthy adult humans as a possible biomarker for environmental exposures to carcinogens.Q53454862
Improved outcome in childhood acute lymphoblastic leukaemia with reinforced early treatment and rotational combination chemotherapyQ68289938
Secondary acute myeloid leukemia in children with acute lymphoblastic leukemia treated with etoposideQ70543495
B-cell non-Hodgkin's lymphoma: evidence for the t (14;18) translocation in all hematopoietic cell lineagesQ71153218
Frequencies of HPRT mutants and micronuclei in lymphocytes of cancer patients under chemotherapy: a prospective studyQ71622602
Somatic mutations at T-cell antigen receptor and glycophorin a loci in pediatric leukemia pateints following chemotherapy: comparison with HPRT locus mutationQ71643050
Relationship between cytotoxicity and site-specific DNA recombination after in vitro exposure of leukemia cells to etoposideQ71878639
Immunological detection of minimal residual disease in children with acute lymphoblastic leukaemiaQ74282286
Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemiasQ24294368
Acute mixed-lineage leukemia t(4;11)(q21;q23) generates an MLL-AF4 fusion productQ24310468
Panhandle PCR strategy to amplify MLL genomic breakpoints in treatment-related leukemiasQ24654907
Structure of the human immunoglobulin μ locus: Characterization of embryonic and rearranged J and D genesQ28259844
Genetic instability in patients with Hodgkin's disease undergoing chemotherapyQ28378917
V(D)J recombination activity in lymphoid cell lines is increased by agents that elevate cAMPQ33915712
Automated DNA sequencing of the human HPRT locusQ34035590
Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocationQ34559025
BCL2 translocation frequency rises with age in humansQ35753763
Interlocus V-J recombination measures genomic instability in agriculture workers at risk for lymphoid malignanciesQ37053952
The (4;11)(q21;q23) chromosome translocations in acute leukemias involve the VDJ recombinaseQ37281612
The clinical pharmacology of etoposide and teniposideQ39658304
Molecular basis of 11q23 rearrangements in hematopoietic malignant proliferations.Q40402872
Topoisomerase II enzymes and mutagenicityQ40590105
Therapy-related acute myeloid leukemia following treatment with epipodophyllotoxins: estimating the risksQ40761813
V(D)J recombinase-mediated deletion of the hprt gene in T-lymphocytes from adult humansQ44067825
Acute myeloid leukemia in children treated with epipodophyllotoxins for acute lymphoblastic leukemiaQ44461372
P433issue1-3
P407language of work or nameEnglishQ1860
P304page(s)107-121
P577publication date1998-11-01
P1433published inMutation ResearchQ6943732
P1476titleThe frequency of illegitimate V(D)J recombinase-mediated mutations in children treated with etoposide-containing antileukemic therapy
P478volume419

Reverse relations

cites work (P2860)
Q80556570Can the genotoxicity of chemotherapy be predicted?
Q34057953Cancer chemotherapy and somatic cell mutation
Q35573350Illegitimate Cre-dependent chromosome rearrangements in transgenic mouse spermatids
Q24812866Qualitatively and quantitatively similar effects of active and passive maternal tobacco smoke exposure on in utero mutagenesis at the HPRT locus
Q73355680Quantification of illegitimate V(D)J recombinase-mediated mutations in lymphocytes of newborns and adults
Q44521593Quantitation of aberrant interlocus T-cell receptor rearrangements in mouse thymocytes and the effect of the herbicide 2,4-dichlorophenoxyacetic acid
Q40829065Temporal delineation of sequential HPRT mutations arising in vivo in a T-cell clone with a mutator phenotype

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