Chelation of iron within the erythrocytic Plasmodium falciparum parasite by iron chelators

scientific article published on 01 June 1999

Chelation of iron within the erythrocytic Plasmodium falciparum parasite by iron chelators is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0166-6851(99)00053-5
P698PubMed publication ID10413042

P50authorValerie W. HuQ52279528
J. Houston MillerQ56892219
P2093author name stringC John
M Loyevsky
V R Gordeuk
B Dickens
P2860cites workHuman malaria parasites in continuous cultureQ28131626
Cloning and characterization of a mammalian proton-coupled metal-ion transporterQ28245045
Natural resistance to infection with intracellular parasites: molecular genetics identifies Nramp1 as the Bcg/Ity/Lsh locusQ28509803
Synchronization of Plasmodium falciparum Erythrocytic Stages in CultureQ29547549
Role of the mitochondrial permeability transition in salicylate toxicity to cultured rat hepatocytes: implications for the pathogenesis of Reye's syndromeQ32137666
Iron chelation therapy for malaria: a reviewQ33537442
High and low affinity Ca2+ binding to the sarcoplasmic reticulum: use of a high-affinity fluorescent calcium indicatorQ34655761
Calcium transport of Plasmodium chabaudi-infected erythrocytesQ36206137
Deferoxamine inhibition of malaria is independent of host iron statusQ36355145
Cloning, sequence determination, and regulation of the ribonucleotide reductase subunits from Plasmodium falciparum: a target for antimalarial therapyQ36584319
Identification of the parasite transferrin receptor of Plasmodium falciparum-infected erythrocytes and its acylation via 1,2-diacyl-sn-glycerolQ37407350
Plasmodicidal effect of desferrioxamine B in human vivax or falciparum malaria from ThailandQ38925729
Chemical Determinants of antimalarial activity of reversed siderophoresQ39782791
The antimalarial action of desferal involves a direct access route to erythrocytic (Plasmodium falciparum) parasitesQ40512718
The biochemical basis for the selective antimalarial action of iron chelators on Plasmodium falciparum parasitized cellsQ40610861
Aminothiol multidentate chelators as antimalarialsQ40883701
Iron chelators: mode of action as antimalarialsQ40972061
Concentration from Continuous Culture of Erythrocytes Infected with Trophozoites and Schizonts of Plasmodium Falciparum *Q40974465
Transport of iron and other transition metals into cells as revealed by a fluorescent probeQ41340992
Iron release and membrane damage in erythrocytes exposed to oxidizing agents, phenylhydrazine, divicine and isouramilQ41839010
Hemin lyses malaria parasitesQ41924272
Inhibition by anti-malarial drugs of haemoglobin denaturation and iron release in acidified red blood cell lysates--a possible mechanism of their anti-malarial effect?Q41935455
Hemozoin production by Plasmodium falciparum: variation with strain and exposure to chloroquine.Q41937349
Inhibition by chloroquine of a novel haem polymerase enzyme activity in malaria trophozoitesQ41940707
Desferrioxamine suppresses Plasmodium falciparum in Aotus monkeysQ43678222
Parasite uptake of desferroxamine: a prerequisite for antimalarial activityQ46158011
A transferrin-independent iron uptake activity in Plasmodium falciparum-infected and uninfected erythrocytesQ47854924
A protein on Plasmodium falciparum-infected erythrocytes functions as a transferrin receptorQ47907949
Plasmodium falciparum: inhibition of in vitro growth by desferrioxamine.Q47986167
Hemoglobin denaturation and iron release in acidified red blood cell lysate--a possible source of iron for intraerythrocytic malaria parasitesQ48017320
Origin of reactive oxygen species in erythrocytes infected with Plasmodium falciparumQ48018663
In vivo antimalarial action of a lipophilic iron (III) chelator: suppression of Plasmodium vinckei infection by reversed siderophore.Q48020639
High-performance liquid chromatographic analysis of biological and chemical heme polymerizationQ48028521
Fluorescence analysis of the labile iron pool of mammalian cells.Q52264375
Chelation of Ferrous Sulphate Solutions by Desferrioxamine BQ59078357
de novo biosynthesis of heme offers a new chemotherapeutic target in the human malarial parasiteQ67521292
Inability to detect transferrin receptors on P. falciparum parasitized red cellsQ68128044
Use of chelating agents to inhibit enzymesQ68375631
Plasmodium falciparum takes up iron from transferrinQ70380208
A fluorescence assay for assessing chelation of intracellular iron in a membrane model system and in mammalian cellsQ71492847
P433issue1-2
P921main subjectPlasmodium falciparumQ311383
P304page(s)43-59
P577publication date1999-06-01
P1433published inMolecular and Biochemical ParasitologyQ15752756
P1476titleChelation of iron within the erythrocytic Plasmodium falciparum parasite by iron chelators
P478volume101

Reverse relations

cites work (P2860)
Q30045593A vacuolar iron-transporter homologue acts as a detoxifier in Plasmodium
Q37338387Anti-plasmodial activity of aroylhydrazone and thiosemicarbazone iron chelators: effect on erythrocyte membrane integrity, parasite development and the intracellular labile iron pool
Q42075825Antibacterial activities of iron chelators against common nosocomial pathogens
Q28483846Antimalarial iron chelator, FBS0701, shows asexual and gametocyte Plasmodium falciparum activity and single oral dose cure in a murine malaria model
Q35121213Assessing Micronutrient Status in the Presence of Inflammation
Q43593356Comparison of hydrophobic charge induction chromatography with affinity chromatography on protein A for harvest and purification of antibodies
Q33491551Determination of the labile iron pool of human lymphocytes using the fluorescent probe, CP655.
Q38372890Microbial siderophores and their potential applications: a review
Q34598463Parasite maturation and host serum iron influence the labile iron pool of erythrocyte stage Plasmodium falciparum
Q34113689Relationship between chloroquine toxicity and iron acquisition in Saccharomyces cerevisiae
Q24681774Siderophore-based iron acquisition and pathogen control

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