Selective regulation of trkC expression by NT3 in the developing peripheral nervous system

scientific article published on 01 August 1999

Selective regulation of trkC expression by NT3 in the developing peripheral nervous system is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1523/JNEUROSCI.19-15-06559.1999
P932PMC publication ID6782807
P698PubMed publication ID10414984

P2093author name stringA M Davies
S Wyatt
G Middleton
E Doxakis
P2860cites worktrkC encodes multiple neurotrophin-3 receptors with distinct biological properties and substrate specificitiesQ24564488
The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domainQ28238459
Disruption of the neurotrophin-3 receptor gene trkC eliminates la muscle afferents and results in abnormal movementsQ28251523
trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factorQ28273781
Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferentsQ28286113
The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptorQ28295368
Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cellsQ28297730
TrkB mediates BDNF/NT-3-dependent survival and proliferation in fibroblasts lacking the low affinity NGF receptorQ28298874
trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3Q28301898
Expression of Trk receptors in the developing mouse trigeminal ganglion: in vivo evidence for NT-3 activation of TrkA and TrkB in addition to TrkCQ28505551
A local action of neurotrophin-3 prevents the death of proliferating sensory neuron precursor cellsQ28508014
Alternative forms of rat TrkC with different functional capabilitiesQ28583560
TrkA, but not TrkC, receptors are essential for survival of sympathetic neurons in vivoQ28594079
The trk proto-oncogene encodes a receptor for nerve growth factorQ28609788
The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3Q34497200
Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF.Q34576586
An alternatively spliced form of the nerve growth factor receptor TrkA confers an enhanced response to neurotrophin 3.Q35897889
Regulation of nerve growth factor receptor gene expression in sympathetic neurons during developmentQ36235983
Characterization of glial trkB receptors: differential response to injury in the central and peripheral nervous systemsQ36329542
Differential expression of nerve growth factor receptors leads to altered binding affinity and neurotrophin responsiveness.Q36493889
Regulation of nerve growth factor receptor gene expression by nerve growth factor in the developing peripheral nervous systemQ36529098
Mammalian neurotrophin-4: structure, chromosomal localization, tissue distribution, and receptor specificityQ36935698
Neurotrophin-3 is a survival factor in vivo for early mouse trigeminal neuronsQ37208132
Characterization of neurotrophin and Trk receptor functions in developing sensory ganglia: direct NT-3 activation of TrkB neurons in vivoQ37263784
Functional analysis of mutant neurotrophins deficient in low-affinity binding reveals a role for p75LNGFR in NT-4 signalling.Q37696831
NGF Amplifies Expression of NGF Receptor Messenger RNA in Forebrain Cholinergic Neurons of RatsQ74428996
Regulation of expression of mRNAs encoding the nerve growth factor receptors p75 and trkA in developing sensory neuronsQ93875267
Selective binding and internalisation by truncated receptors restrict the availability of BDNF during development.Q38292846
Colocalization of NGF binding sites, trk mRNA, and low-affinity NGF receptor mRNA in primary sensory neurons: responses to injury and infusion of NGFQ38325531
Functional Interactions of Neurotrophins and Neurotrophin ReceptorsQ40441056
The role of neurotrophins in the developing nervous systemQ40590879
Functions of the neurotrophins during nervous system development: what the knockouts are teaching us.Q40763660
Developmental changes in NT3 signalling via TrkA and TrkB in embryonic neurons.Q40789379
Expression and function of TrkB variants in developing sensory neurons.Q41078653
Novel roles for neurotrophins are suggested by BDNF and NT-3 mRNA expression in developing neuronsQ41088924
Physiology of the neurotrophinsQ41132669
Neurotrophin switching: where does it stand?Q41353337
Neurotrophin-5: A novel neurotrophic factor that activates trk and trkBQ41658559
High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptorQ41687095
Sympathetic neuron survival and TrkA expression in NT3-deficient mouse embryos.Q41829028
Differential expression of mRNAs for neurotrophins and their receptors after axotomy of the sciatic nerveQ42056826
Absence of p75NTR causes increased basal forebrain cholinergic neuron size, choline acetyltransferase activity, and target innervation.Q42444976
Nerve growth factor (NGF)-mediated up-regulation of low-affinity NGF receptor gene expression in cultured basal forebrain cholinergic neurons from postnatal 3-day-old ratsQ42452770
Molecular cloning of rat trkC and distribution of cells expressing messenger RNAs for members of the trk family in the rat central nervous systemQ42458072
p140trk mRNA marks NGF-responsive forebrain neurons: evidence that trk gene expression is induced by NGFQ42458990
Nerve growth factor differentially modulates the expression of its receptor within the CNS.Q42463685
Reciprocal regulation of estrogen and NGF receptors by their ligands in PC12 cells.Q42476656
NGF induction of NGF receptor gene expression and cholinergic neuronal hypertrophy within the basal forebrain of the adult rat.Q42494413
Nerve growth factor induces trkA mRNA expression in cultured basal forebrain cholinergic neurons from 17-day fetal ratsQ42496032
Expression of neurotrophin and trk receptor genes in adult rats with fimbria transections: effect of intraventricular nerve growth factor and brain-derived neurotrophic factor administrationQ42496429
Survival of cholinergic forebrain neurons in developing p75NGFR-deficient miceQ42527534
Lack of neurotrophin-3 results in death of spinal sensory neurons and premature differentiation of their precursorsQ42578317
Differential modulation of neuron survival during development by nerve growth factor binding to the p75 neurotrophin receptorQ42799493
The rat trkC locus encodes multiple neurogenic receptors that exhibit differential response to neurotrophin-3 in PC12 cellsQ42809847
Neurotrophins regulate sequential changes in neurotrophin receptor expression by sympathetic neuroblastsQ43473220
Expression of the tyrosine kinase receptor gene trkB is confined to the murine embryonic and adult nervous systemQ43512347
The survival and growth of embryonic proprioceptive neurons is promoted by a factor present in skeletal muscleQ44788819
Induction of noncatalytic TrkB neurotrophin receptors during axonal sprouting in the adult hippocampusQ46743236
TrkB signalling inhibits p75-mediated apoptosis induced by nerve growth factor in embryonic proprioceptive neuronsQ47674900
Different neurotrophins are expressed and act in a developmental sequence to promote the survival of embryonic sensory neuronsQ48263160
Timing and regulation of trkB and BDNF mRNA expression in placode-derived sensory neurons and their targetsQ48873108
Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75.Q48887712
Nerve growth factor derived from terminals selectively increases the ratio of p75 to trkA NGF receptors on mature sympathetic neurons.Q50776082
Timing of neuronal death in trkA, trkB and trkC mutant embryos reveals developmental changes in sensory neuron dependence on Trk signalling.Q52199659
Developing inner ear sensory neurons require TrkB and TrkC receptors for innervation of their peripheral targetsQ52205757
NGF receptor expression in sensory neurons develops normally in embryos lacking NGF.Q52205825
Expression of trk and neurotrophin mRNA in dorsal root and sympathetic ganglia of the quail during development.Q52212681
Relation of target encounter and neuronal death to nerve growth factor responsiveness in the developing mouse trigeminal ganglion.Q52276034
Induction of cell death by endogenous nerve growth factor through its p75 receptorQ58047180
Requirement of neurotrophin-3 for the survival of proliferating trigeminal ganglion progenitor cellsQ60695078
A novel modular mosaic of cell adhesion motifs in the extracellular domains of the neurogenic trk and trkB tyrosine kinase receptorsQ68258208
The survival of early chick sympathetic neurons in vitro is dependent on a suitable substrate but independent of NGFQ69721319
Factors controlling the expression of the NGF receptor in PC12 cellsQ69841890
p75-deficient trigeminal sensory neurons have an altered response to NGF but not to other neurotrophinsQ70478360
Trigeminal sensory neurons require extrinsic signals to switch neurotrophin dependence during the early stages of target field innervationQ71736886
Truncated and catalytic isoforms of trkB are co-expressed in neurons of rat and mouse CNSQ71795858
p75-deficient embryonic dorsal root sensory and neonatal sympathetic neurons display a decreased sensitivity to NGFQ71845313
Role of transforming growth factor-beta isoforms in regulating the expression of nerve growth factor and neurotrophin-3 mRNA levels in embryonic cutaneous cells at different stages of developmentQ72106583
Neurotrophic factor receptors and their signal transduction capabilities in rat astrocytesQ72162022
NGF binding to p75 enhances the sensitivity of sensory and sympathetic neurons to NGF at different stages of developmentQ74415738
Nerve Growth Factor Regulates Expression of the Nerve Growth Factor Receptor Gene in Adult Sensory NeuronsQ74428639
P433issue15
P304page(s)6559-6570
P577publication date1999-08-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleSelective regulation of trkC expression by NT3 in the developing peripheral nervous system
P478volume19

Reverse relations

cites work (P2860)
Q35403529Chinese herbal formula Tongluo Jiunao injection protects against cerebral ischemia by activating neurotrophin 3/tropomyosin-related kinase C pathway
Q42113611Differential phosphorylation of Smad1 integrates BMP and neurotrophin pathways through Erk/Dusp in axon development.
Q37260462Diverse dependencies of developing Merkel innervation on the trkA and both full-length and truncated isoforms of trkC.
Q34662661Morphometric analysis of embryonic rat trigeminal neurons treated with different neurotrophins
Q44597445Neurotrophin‐3 down‐regulates trkA mRNA, NGF high‐affinity binding sites, and associated phenotype in adult DRG neurons
Q36519997The Transcriptional Response of Neurotrophins and Their Tyrosine Kinase Receptors in Lumbar Sensorimotor Circuits to Spinal Cord Contusion is Affected by Injury Severity and Survival Time.
Q48155108The effects of deafferentation and exogenous NGF on neurotrophins and neurotrophin receptor mRNA expression in the adult superior cervical ganglion

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