The use of perfusion CT for the evaluation of therapy combining AZD2171 with gefitinib in cancer patients

scientific article published on 27 October 2006

The use of perfusion CT for the evaluation of therapy combining AZD2171 with gefitinib in cancer patients is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00330-006-0425-9
P698PubMed publication ID17072618

P50authorGiuseppe GiacconeQ37829946
Martijn R MeijerinkQ43182951
P2093author name stringRadu A Manoliu
Hester van Cruijsen
Klaas Hoekman
Jan Hein T M van Waesberghe
Matthijs Kater
Cors van Schaik
P2860cites workTumor angiogenesis: therapeutic implicationsQ27860595
New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of CanadaQ27860904
AZD2171: a highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancerQ28251373
Normalization of tumor vasculature: an emerging concept in antiangiogenic therapyQ29547379
Toxicity and response criteria of the Eastern Cooperative Oncology GroupQ29619399
Quantitative perfusion map of malignant liver tumors, created from dynamic computed tomography dataQ30907241
62Cu-PTSM and PET used for the assessment of angiotensin II-induced blood flow changes in patients with colorectal liver metastasesQ32002205
Hepatic perfusion parameters in chronic liver disease: dynamic CT measurements correlated with disease severityQ32061742
Estimating kinetic parameters from dynamic contrast-enhanced T(1)-weighted MRI of a diffusable tracer: standardized quantities and symbols.Q33744660
Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trialQ34271566
Perfusion imaging of the liver: current challenges and future goalsQ34398265
Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [corrected].Q34533636
Imaging angiogenesis: applications and potential for drug developmentQ36027611
The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations.Q36616812
Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancerQ37219981
Rim enhancement in colorectal metastases at CT during infusion hepatic arteriography. Does it represent liver parenchyma or live tumor cell zone?Q39447358
A physiologic imaging pilot study of breast cancer treated with AZD2171.Q40333245
Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases.Q40479307
Improving the detection of hepatic metastases by the use of dynamic flow scintigraphyQ41509313
First-pass measurements of regional blood flow with external detectorsQ41585516
Colour perfusion imaging: a new application of computed tomographyQ41787650
Evaluation of the anti-vascular effects of combretastatin in rodent tumours by dynamic contrast enhanced MRI.Q43900373
Measuring portal venous perfusion with contrast-enhanced CT: comparison of direct and indirect methodsQ43914801
Perfusion of colorectal hepatic metastases. Relative distribution of flow from the hepatic artery and portal veinQ44266901
The portal component of hepatic perfusion measured by dynamic CT: an indicator of hepatic parenchymal damageQ44762666
Perfusion CT in patients with advanced bronchial carcinomas: a novel chance for characterization and treatment monitoring?Q44804423
Measurement of tissue perfusion by dynamic computed tomographyQ44997256
Measurement of regional cerebral blood flow using ultrafast computed tomography. Theoretical aspects.Q46036593
MRI assessment of microvascular characteristics in experimental breast tumors using a new blood pool contrast agent (MS-325) with correlations to histopathology.Q46089577
Phase I study of the safety, tolerability, pharmacokinetics, and pharmacodynamics of PTK787/ZK 222584 administered twice daily in patients with advanced cancerQ46468963
Assessment of inter- and intrapatient variability in C15O2 positron emission tomography measurements of blood flow in patients with intra-abdominal cancers.Q47297737
Tumor perfusion rate determined noninvasively by dynamic computed tomography predicts outcome in head-and-neck cancer after radiotherapyQ47373010
Breath-hold perfusion and permeability mapping of hepatic malignancies using magnetic resonance imaging and a first-pass leakage profile model.Q51725613
Non-invasive quantification of liver perfusion with dynamic computed tomography and a dual-input one-compartmental model.Q52070479
Derivation of gamma variate indicator dilution function from simple convective dispersion model of blood flow.Q52431974
Cerebral blood flow determination by rapid-sequence computed tomography: theoretical analysis.Q52751958
A phase I surrogate endpoint study of SU6668 in patients with solid tumors.Q53615730
Early modifications of hepatic perfusion measured by functional CT in a rat model of hepatocellular carcinoma using a blood pool contrast agentQ59510517
Reproducibility of quantitative dynamic MRI of normal human tissuesQ62612608
Quantification of perfusion of liver tissue and metastases using a multivessel model for replenishment kinetics of ultrasound contrast agents.Q64025807
Hepatic perfusion changes in mice livers with developing colorectal cancer metastases.Q64948664
Liver perfusion studied with ultrafast CTQ72334213
Functional images of hepatic perfusion obtained with dynamic CTQ72822410
Splenic blood flow: evaluation with computed tomographyQ73090288
CT assessment of cerebral perfusion: experimental validation and initial clinical experienceQ73130085
Lung nodule enhancement at CT: multicenter studyQ73375528
9:00-9:15. Antiangiogenic Treatment with Endostatin Results in Uncoupling of Blood Flow and Glucose Metabolism in Human TumorsQ73379275
A CT method to measure hemodynamics in brain tumors: validation and application of cerebral blood flow mapsQ73578659
Solitary pulmonary nodules: evaluation of blood flow patterns with dynamic CTQ73843574
Colorectal cancer: diagnostic potential of CT measurements of hepatic perfusion and implications for contrast enhancement protocolsQ73931348
Reproducibility of quantitative CT perfusion imagingQ74222592
In vivo assessment of neovascularization of liver metastases using perfusion CTQ74620633
Development of perfusion CT software for personal computersQ74627069
The theory and applications of the exchange of inert gas at the lungs and tissuesQ75726399
Does the presence of distant and local malignancy alter parenchymal perfusion in apparently disease-free areas of the liver?Q77073447
Assessment of hepatic perfusion parameters with dynamic MRIQ77382106
Regional blood flow, capillary permeability, and compartmental volumes: measurement with dynamic CT--initial experienceQ77785612
CT measurement of perfusion and permeability within lymphoma masses and its ability to assess grade, activity, and chemotherapeutic responseQ78086655
Phase I pharmacokinetic and pharmacodynamic study of recombinant human endostatin in patients with advanced solid tumorsQ78785324
P433issue7
P304page(s)1700-1713
P577publication date2006-10-27
P1433published inEuropean RadiologyQ5413071
P1476titleThe use of perfusion CT for the evaluation of therapy combining AZD2171 with gefitinib in cancer patients
P478volume17

Reverse relations

cites work (P2860)
Q35798947Anti-angiogenic activity of VXM01, an oral T-cell vaccine against VEGF receptor 2, in patients with advanced pancreatic cancer: A randomized, placebo-controlled, phase 1 trial.
Q47552136Appraisal of radiation dose with 64-slice computed tomography perfusion in lung cancer patients with special reference to SSDE: An initial experience in a tertiary care hospital
Q51853080Assessment of the spatial pattern of colorectal tumour perfusion estimated at perfusion CT using two-dimensional fractal analysis.
Q37693472CT perfusion in oncology: how to do it.
Q36558272CTA combined with CT perfusion for assessing the efficacy of anti-angiogenic therapy in rabbit VX2 tumors
Q45001364CTA-enhanced perfusion CT: an original method to perform ultra-low-dose CTA-enhanced perfusion CT.
Q44939902Can perfusion CT assessment of primary colorectal adenocarcinoma blood flow at staging predict for subsequent metastatic disease? A pilot study
Q53268488Commercial software upgrades may significantly alter Perfusion CT parameter values in colorectal cancer.
Q36347036Comparison of free breathing versus breath-hold in perfusion imaging using dynamic volume CT
Q39647845Current status and guidelines for the assessment of tumour vascular support with dynamic contrast-enhanced computed tomography
Q57177411Dynamic contrast-enhanced CT for the assessment of tumour response in malignant pleural mesothelioma: a pilot study
Q34298000Dynamic contrast-enhanced CT in patients treated with sorafenib and erlotinib for non-small cell lung cancer: a new method of monitoring treatment?
Q30475764Estimation of intra-operator variability in perfusion parameter measurements using DCE-US.
Q26860708Functional imaging biomarkers for assessing response to treatment in liver and lung metastases
Q39814899Hepatic Perfusion Imaging: Concepts and Application
Q37356037Morphological and functional MDCT: problem-solving tool and surrogate biomarker for hepatic disease clinical care and drug discovery in the era of personalized medicine
Q42923595Perfusion CT and US of colorectal cancer liver metastases: a correlative study of two dynamic imaging modalities.
Q37707171Perfusion CT in solid body-tumours. Part II: Clinical applications and future development.
Q34427108Perfusion characterization of liver metastases from endocrine tumors: Computed tomography perfusion
Q33764784Perfusion magnetic resonance imaging of the liver
Q37392001Perfusion-CT monitoring of cryo-ablated renal cells tumors
Q33796799Protocol modifications for CT perfusion (CTp) examinations of abdomen-pelvic tumors: impact on radiation dose and data processing time
Q46693507Quantitative mapping of hepatic perfusion index using MR imaging: a potential reproducible tool for assessing tumour response to treatment with the antiangiogenic compound BIBF 1120, a potent triple angiokinase inhibitor.
Q33857343RECIST revised: implications for the radiologist. A review article on the modified RECIST guideline
Q82495518Radiation dose from volumetric helical perfusion CT of the thorax, abdomen or pelvis
Q33567345Response Evaluation of Chemotherapy for Lung Cancer
Q34088696Targeted therapies in renal cell cancer: recent developments in imaging
Q53199563The value of perfusion CT in predicting the short-term response to synchronous radiochemotherapy for cervical squamous cancer.
Q51878570Total-liver-volume perfusion CT using 3-D image fusion to improve detection and characterization of liver metastases.
Q37760857Tracer kinetic modelling of tumour angiogenesis based on dynamic contrast-enhanced CT and MRI measurements

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