EGF AND TGF-alpha motogenic activities are mediated by the EGF receptor via distinct matrix-dependent mechanisms

scientific article published on 05 December 2006

EGF AND TGF-alpha motogenic activities are mediated by the EGF receptor via distinct matrix-dependent mechanisms is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.YEXCR.2006.11.016
P698PubMed publication ID17196962

P50authorIan EllisQ67554645
P2093author name stringAna M Schor
Seth L Schor
P2860cites workPhenotypic and genetic alterations in mammary stroma: implications for tumour progressionQ21195198
Negative regulation of EGFR signalling through integrin-alpha1beta1-mediated activation of protein tyrosine phosphatase TCPTPQ24321559
Hyaluronan promotes CD44v3-Vav2 interaction with Grb2-p185(HER2) and induces Rac1 and Ras signaling during ovarian tumor cell migration and growthQ28199263
An open-and-shut case? Recent insights into the activation of EGF/ErbB receptorsQ28207289
Integrin regulation of epidermal growth factor (EGF) receptor and of EGF-dependent responsesQ28262897
Hyaluronan-CD44 interaction with leukemia-associated RhoGEF and epidermal growth factor receptor promotes Rho/Ras co-activation, phospholipase C epsilon-Ca2+ signaling, and cytoskeleton modification in head and neck squamous cell carcinoma cellsQ28303871
Alterations of vitronectin and its receptor alpha(v) integrin in the rat renal glomerular wall during diabetesQ28580731
Alphavbeta3 integrin associates with activated insulin and PDGFbeta receptors and potentiates the biological activity of PDGFQ33887469
A hierarchy of ECM-mediated signalling regulates tissue-specific gene expressionQ34103381
An integrated model of epidermal growth factor receptor trafficking and signal transductionQ34182212
Epidermal growth factor receptor: mechanisms of activation and signalling.Q34185055
Signaling properties of hyaluronan receptorsQ34444928
EGFR signal transactivation in cancer cellsQ35594162
Role of HER receptors family in development and differentiation.Q35837065
A variant epidermal growth factor receptor exhibits altered type alpha transforming growth factor binding and transmembrane signalingQ35841864
Alphavbeta6 integrin in wound healing and cancer of the oral cavityQ36360521
Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective in epithelial biologyQ36755844
Tumor cells enhance their own CD44 cleavage and motility by generating hyaluronan fragmentsQ40331251
Cytokine control of cell motility: modulation and mediation by the extracellular matrixQ40627368
EGF upregulates, whereas TGF-beta downregulates, the hyaluronan synthases Has2 and Has3 in organotypic keratinocyte cultures: correlations with epidermal proliferation and differentiationQ40642521
CD44 stimulation by fragmented hyaluronic acid induces upregulation of urokinase-type plasminogen activator and its receptor and subsequently facilitates invasion of human chondrosarcoma cellsQ40694018
Interaction between the adhesion receptor, CD44, and the oncogene product, p185HER2, promotes human ovarian tumor cell activationQ41083579
Receptor-mediated effects on ligand availability influence relative mitogenic potencies of epidermal growth factor and transforming growth factor alphaQ41225764
Differential regulation by IL-1beta and EGF of expression of three different hyaluronan synthases in oral mucosal epithelial cells and fibroblasts and dermal fibroblasts: quantitative analysis using real-time RT-PCR.Q44846059
Changes in the extracellular matrix of the normal human breast during the menstrual cycleQ45256160
Epidermal growth factor and transforming growth factor alpha bind differently to the epidermal growth factor receptorQ46051292
Age-related changes in hyaluronan, proteoglycan, collagen, and osteonectin synthesis by human bone cells.Q52421615
A novel 'sandwich' assay for quantifying chemo-regulated cell migration within 3-dimensional matrices: wound healing cytokines exhibit distinct motogenic activities compared to the transmembrane assay.Q53000312
The EGF receptor: a nexus for trafficking and signalingQ56059793
Enhanced modulation of keratinocyte motility by transforming growth factor-alpha (TGF-alpha) relative to epidermal growth factor (EGF)Q71049491
Motogenic and biosynthetic response of adult skin fibroblasts to TGF-beta isoforms (-1, -2 and -3) determined by 'tissue response unit': role of cell density and substratumQ73574063
Comparative mitogenic potencies of EGF and TGF alpha and their dependence on receptor-limitation versus ligand-limitationQ77307797
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)732-741
P577publication date2006-12-05
P1433published inExperimental Cell ResearchQ1524289
P1476titleEGF AND TGF-alpha motogenic activities are mediated by the EGF receptor via distinct matrix-dependent mechanisms
P478volume313

Reverse relations

cites work (P2860)
Q42914728A novel fragment derived from the beta chain of human fibrinogen, beta43-63, is a potent inhibitor of activated endothelial cells in vitro and in vivo
Q39403006Aging fibroblasts resist phenotypic maturation because of impaired hyaluronan-dependent CD44/epidermal growth factor receptor signaling.
Q37698606Autocrine-derived epidermal growth factor receptor ligands contribute to recruitment of tumor-associated macrophage and growth of basal breast cancer cells in vivo.
Q40065097Co-expression by keratinocytes of migration stimulating factor (MSF) and a functional inhibitor of its bioactivity (MSFI).
Q34249179Different epidermal growth factor (EGF) receptor ligands show distinct kinetics and biased or partial agonism for homodimer and heterodimer formation
Q50100847Differential recruitment of CD44 isoforms by ErbB ligands reveals an involvement of CD44 in breast cancer.
Q37149729Functional selectivity of EGF family peptide growth factors: implications for cancer
Q42733192Hyaluronan facilitates transforming growth factor-β1-dependent proliferation via CD44 and epidermal growth factor receptor interaction
Q43093528Multi-factorial modulation of IGD motogenic potential in MSF (migration stimulating factor).
Q37970313Regenerative potential of glycosaminoglycans for skin and bone.
Q37422984Relationship between EGF, TGFA, and EGFR Gene Polymorphisms and Traditional Chinese Medicine ZHENG in Gastric Cancer
Q42347025Sorafenib controls the epithelial‑mesenchymal transition of ovarian cancer cells via EGF and the CD44‑HA signaling pathway in a cell type‑dependent manner
Q39472524The control and importance of hyaluronan synthase expression in palatogenesis
Q34339468Transforming growth factor-β1 (TGF-β1)-stimulated fibroblast to myofibroblast differentiation is mediated by hyaluronan (HA)-facilitated epidermal growth factor receptor (EGFR) and CD44 co-localization in lipid rafts
Q33610372Wounding-induced synthesis of hyaluronic acid in organotypic epidermal cultures requires the release of heparin-binding egf and activation of the EGFR

Search more.