Androgens and bone

scientific article published on 17 October 2008

Androgens and bone is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.STEROIDS.2008.10.003
P932PMC publication ID2679948
P698PubMed publication ID18992761

P50authorSundeep KhoslaQ42164143
P2093author name stringBart L Clarke
P2860cites workDehydroepiandrosterone (DHEA), DHEA sulfate, and aging: contribution of the DHEAge Study to a sociobiomedical issueQ24679625
Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand familiesQ28137631
The Impact of Gonadal Steroid Hormone Action on Growth Hormone Secretion During Childhood and Adolescence*Q30438131
Sex steroids and boneQ31817124
Localization of estrogen receptor beta protein expression in adult human bone.Q32006661
Free testosterone is an independent predictor of BMD and prevalent fractures in elderly men: MrOS SwedenQ33239089
The effects of testosterone on osteoporosis in men.Q33723618
Steroid hormone receptor expression and action in boneQ33829036
Identification of androgen receptors in normal human osteoblast-like cellsQ33834413
Spironolactone, but not flutamide, administration prevents bone loss in hyperandrogenic women treated with gonadotropin-releasing hormone agonistQ33858495
Effects of transdermal testosterone on bone and muscle in older men with low bioavailable testosterone levelsQ33943952
The effects of oestrogens on linear bone growthQ33949996
DHEA in elderly women and DHEA or testosterone in elderly men.Q34000294
Clinical Review 116: Bone mineral density, androgens, and the polycystic ovary: the complex and controversial issue of androgenic influence in female boneQ34075696
Calcium and protein kinetics in prepubertal boys. Positive effects of testosteroneQ34131306
Sex steroids and the construction and conservation of the adult skeletonQ34131889
Regulation of interleukin-6, osteoclastogenesis, and bone mass by androgens. The role of the androgen receptorQ34224435
Population-based study of age and sex differences in bone volumetric density, size, geometry, and structure at different skeletal sitesQ34366766
Treatment of isolated hypogonadotropic hypogonadism effect on bone mineral density and bone turnover.Q34415758
Altered bone mineral density in patients with complete androgen insensitivity syndrome.Q34492145
Clinical review 144: Estrogen and the male skeletonQ34587203
Transcriptional up-regulation of the human androgen receptor by androgen in bone cellsQ34740453
Androgens regulate bone resorption activity of isolated osteoclasts in vitroQ34818200
Osteoporosis during androgen deprivation therapy for prostate cancerQ34856701
Estradiol, testosterone, and the risk for hip fractures in elderly men from the Framingham StudyQ36465030
Short-term effect of testosterone treatment on reduced bone density in boys with constitutional delay of pubertyQ36805507
Relative contributions of testosterone and estrogen in regulating bone resorption and formation in normal elderly menQ37272054
Expression of the vitamin D receptor, of estrogen and thyroid hormone receptor alpha- and beta-isoforms, and of the androgen receptor in cultures of native mouse bone marrow and of stromal/osteoblastic cellsQ38324907
Endogenous sex hormones and incident fracture risk in older men: the Dubbo Osteoporosis Epidemiology Study.Q40134234
Regulation of osteoprotegerin production by androgens and anti-androgens in human osteoblastic lineage cells.Q40713758
Determinants of bone density in healthy older men with low testosterone levelsQ40747297
Androgens suppress osteoclast formation induced by RANKL and macrophage-colony stimulating factorQ40784699
Homologous androgen receptor up-regulation in osteoblastic cells may be associated with enhanced functional androgen responsivenessQ40945365
Effects of gonadal and adrenal androgens in a novel androgen-responsive human osteoblastic cell lineQ41009217
Low levels of estradiol are associated with vertebral fractures in older men, but not women: the Rancho Bernardo StudyQ41714023
Transdermal testosterone gel improves sexual function, mood, muscle strength, and body composition parameters in hypogonadal men.Q41756245
Androgen supplementation in eugonadal men with osteoporosis-effects of 6 months of treatment on bone mineral density and cardiovascular risk factorsQ42639872
Bone mineral density and quantitative ultrasound parameters in patients with Klinefelter's syndrome after long-term testosterone substitution.Q43576962
Bone loss in men with prostate cancer treated with gonadotropin-releasing hormone agonistsQ43633903
The effect of aromatase inhibition on sex steroids, gonadotropins, and markers of bone turnover in older men.Q43633936
Effects of transdermal testosterone gel on bone turnover markers and bone mineral density in hypogonadal men.Q43650554
A double-blind, placebo-controlled, randomized clinical trial of transdermal dihydrotestosterone gel on muscular strength, mobility, and quality of life in older men with partial androgen deficiencyQ43732380
Pamidronate to prevent bone loss during androgen-deprivation therapy for prostate cancerQ43749401
Effects of raloxifene, a selective estrogen receptor modulator, on bone turnover markers and serum sex steroid and lipid levels in elderly men.Q43791669
Pathogenesis of vertebral crush fractures in menQ43982053
Human osteoblast-like cells express predominantly steroid 5alpha-reductase type 1.Q44238589
Differential effects of androgens and estrogens on bone turnover in normal men.Q44273273
Direct modulation by estradiol of the response of human bone cells (SaOS-2) to human parathyroid hormone (PTH) and PTH-related proteinQ44345535
Androgens directly stimulate proliferation of bone cells in vitroQ44363251
A prospective study of dehydroepiandrosterone sulfate (DHEAS) and bone mineral density in older men and womenQ44709949
Sex hormones mediate interleukin-1β production by human osteoblastic HOBIT cellsQ45082467
Sublingual testosterone replacement improves muscle mass and strength, decreases bone resorption, and increases bone formation markers in hypogonadal men--a clinical research center study.Q46080336
Studies of the mechanism by which androgens enhance mitogenesis and differentiation in bone cellsQ46259138
Endogenous sex steroids and bone mineral density in older women and men: the Rancho Bernardo StudyQ46270750
Does hypogonadism contribute to the occurrence of a minimal trauma hip fracture in elderly men?Q46492115
Effect of testosterone treatment on bone mineral density in men over 65 years of age.Q48759951
Long-term effect of testosterone therapy on bone mineral density in hypogonadal men.Q50623955
Relationship of serum sex steroid levels and bone turnover markers with bone mineral density in men and women: a key role for bioavailable estrogen.Q50877209
Age-related (type II) femoral neck osteoporosis in men: biochemical evidence for both hypovitaminosis D- and androgen deficiency-induced bone resorption.Q50915518
Skeletal site-dependent expression of the androgen receptor in human osteoblastic cell populations.Q50921556
Marked decline in serum concentrations of adrenal C19 sex steroid precursors and conjugated androgen metabolites during aging.Q50941992
Androgen-receptor blockade does not impair bone mineral density in adolescent females.Q50950580
Estrogen, progesterone and testosterone receptors in human fetal cartilaginous tissue: immunohistochemical studies.Q50954072
Comparison of the effects of estrogen alone and estrogen plus androgen on biochemical markers of bone formation and resorption in postmenopausal women.Q51044416
Bone histomorphometry in hypogonadal and eugonadal men with spinal osteoporosis.Q51629207
Direct administration of testosterone increases rat tibial epiphyseal growth plate width.Q52244989
Effects of testosterone replacement in hypogonadal men.Q52970270
Finasteride therapy does not alter bone turnover in men with benign prostatic hyperplasia--a Clinical Research Center study.Q53811664
Increases in bone density during treatment of men with idiopathic hypogonadotropic hypogonadism.Q54104714
Spironolactone, But Not Flutamide, Administration Prevents Bone Loss in Hyperandrogenic Women Treated with Gonadotropin-Releasing Hormone Agonist1Q56429446
Androgens and BoneQ57606357
Effect of testosterone therapy on bone formation in an osteoporotic hypogonadal maleQ58086773
Demonstration of Estrogen Receptor-β Immunoreactivity in Human Growth Plate CartilageQ61480392
Prolonged treatment with finasteride (a 5α‐reductase inhibitor) does not affect bone density and metabolismQ67467248
Effects of androgens on parathyroid hormone and interleukin-1-stimulated prostaglandin production in cultured neonatal mouse calvariaeQ68648059
Biological effects of androgens and identification of specific dihydrotestosterone-binding sites in cultured human fetal epiphyseal chondrocytesQ68690362
Osteoporosis in hypogonadal men: role of decreased plasma 1,25-dihydroxyvitamin D, calcium malabsorption, and low bone formationQ69636878
Effect of excess endogenous androgens on bone density in young womenQ70063539
High bone density in hyperandrogenic women: effect of gonadotropin-releasing hormone agonist alone or in conjunction with estrogen-progestin replacementQ71091887
Testosterone therapy in glucocorticoid-treated menQ71098016
Risk factors for spinal osteoporosis in menQ71123827
A longitudinal evaluation of bone mineral density in adult men with histories of delayed pubertyQ71441877
Increase in bone density and lean body mass during testosterone administration in men with acquired hypogonadismQ71857797
Androgens and boneQ71916439
Immunocytochemical identification of androgen receptor in mouse osteoclast-like multinucleated cellsQ72132570
Antiandrogen treatment with spironolactone and linestrenol decreases bone mineral density in eumenorrhoeic women with androgen excessQ72346200
Gonadal and adrenal androgens are potent regulators of human bone cell metabolism in vitroQ73168558
Effects of DHEA replacement on bone mineral density and body composition in elderly women and menQ73270915
The localization of androgen receptors in human boneQ73785087
Estrogen receptors alpha and beta are differentially expressed in developing human boneQ73853603
Effects of testosterone replacement therapy on cortical and trabecular bone mineral density, vertebral body area and paraspinal muscle area in hypogonadal menQ74166335
Gender differences in expression of androgen receptor in tibial growth plate and metaphyseal bone of the ratQ74252553
Sex steroid metabolism in the tibial growth plate of the ratQ74805683
Changes in bone mineral density after orchidectomy and hormone replacement therapy in individuals with androgen insensitivity syndromeQ77519218
Normal volumetric bone mineral density and bone turnover in young men with histories of constitutional delay of pubertyQ77676740
P433issue3
P304page(s)296-305
P577publication date2008-10-17
P1433published inSteroidsQ15716675
P1476titleAndrogens and bone
P478volume74

Reverse relations

cites work (P2860)
Q28066891A concise review of testosterone and bone health
Q38021668AST-induced bone loss in men with prostate cancer: exercise as a potential countermeasure
Q46258479Additive genetic variation in the craniofacial skeleton of baboons (genus Papio) and its relationship to body and cranial size.
Q35774987Androgen-deprivation therapy and bone loss in prostate cancer patients: a clinical review
Q90292888Anorexia Nervosa and Osteoporosis: Pathophysiology and Treatment
Q35101538Aromatase activity and bone loss in men.
Q55342099Bioavailable Testosterone Is Positively Associated With Bone Mineral Density in Male Kidney Transplantation Candidates.
Q55003255Bone Cell Activity in Clinical Prostate Cancer Bone Metastasis and Its Inverse Relation to Tumor Cell Androgen Receptor Activity.
Q64266776Bone as a Preferential Site for Metastasis
Q27025688Bone health and associated metabolic complications in neuromuscular diseases
Q36259458Bone metastasis and the metastatic niche
Q40107245Bone mineral density in people living with HIV: a narrative review of the literature.
Q49211720Cancer Treatment and Bone Health
Q58101753Chemokine-like receptor 1 deficiency leads to lower bone mass in male mice
Q36538137Different effects of an extended photoperiod treatment on growth, gonadal function, and condition of hair coats in Thoroughbred yearlings reared under different climate conditions
Q47145924Dihydrotestosterone, a robust promoter of osteoblastic proliferation and differentiation: understanding of time-mannered and dose-dependent control of bone forming cells
Q60182871Dissection of genetic variation and evidence for pleiotropy in male pattern baldness
Q64993063Effects of androgen and progestin on the proliferation and differentiation of osteoblasts.
Q44619585Effects of testosterone replacement therapy on bone metabolism in male post-surgical hypogonadotropic hypogonadism: focus on the role of androgen receptor CAG polymorphism
Q37520591Estrogens as regulators of bone health in men.
Q40577247Exploratory analysis of the potential relationship between urinary molybdenum and bone mineral density among adult men and women from NHANES 2007-2010.
Q36059394Glucocorticoid-induced osteoporosis: treatment update and review.
Q34758514Higher serum free testosterone concentration in older women is associated with greater bone mineral density, lean body mass, and total fat mass: the cardiovascular health study
Q41997349Increased Risk of Osteoporosis in Depressive Patients with Erectile Dysfunction: A Cross-sectional Study from Malaysia
Q36572240Local delivery of a selective androgen receptor modulator failed as an anabolic agent in a rat bone marrow ablation model
Q34134467Long‐Term Effects of Dimethandrolone 17β‐Undecanoate and 11β‐Methyl‐19‐Nortestosterone 17β‐Dodecylcarbonate on Body Composition, Bone Mineral Density, Serum Gonadotropins, and Androgenic/Anabolic Activity in Castrated Male Rats
Q50998338Low bone mineral density for age/osteoporosis in triple A syndrome-an overlooked symptom of unexplained etiology.
Q64999428Male osteoporosis: do sex steroids really benefit bone health in men?
Q41245485Marrow Adipose Tissue: Skeletal Location, Sexual Dimorphism, and Response to Sex Steroid Deficiency.
Q58611982Osteoporosis and dry eye syndrome: A previously unappreciated association that may alert active prevention of fall
Q92746416Per- and Polyfluoroalkyl Substance Plasma Concentrations and Bone Mineral Density in Midchildhood: A Cross-Sectional Study (Project Viva, United States)
Q33980978Physiology of bone loss
Q34117906Profiling insulin like factor 3 (INSL3) signaling in human osteoblasts
Q31121010Pubertal Stress and Nutrition and their Association with Sexual Orientation and Height in the Add Health Data
Q89013927Reproduction triggers adaptive increases in body size in female mole-rats
Q34112663Reproductive hormones and bone
Q39316805Revisiting the role of testosterone: Are we missing something?
Q92305299Risk Factors for Development of Canine and Human Osteosarcoma: A Comparative Review
Q40227719Sex hormone levels as determinants of bone mineral density and osteoporosis in Vietnamese women and men.
Q55269687Significant improvement of bone mineral density by denosumab treatment in Japanese osteoporotic patients following breast cancer treatment.
Q59125726Stanozolol promotes osteogenic gene expression and apposition of bone mineral in vitro
Q92495177Systematic Review of the Long-Term Effects of Transgender Hormone Therapy on Bone Markers and Bone Mineral Density and Their Potential Effects in Implant Therapy
Q38121742Testicular function and bone metabolism--beyond testosterone
Q38584377Testosterone in women--the clinical significance
Q35910549Testosterone regulates bone response to inflammation.
Q98735476The Effects of Androgens on T Cells: Clues to Female Predominance in Autoimmune Liver Diseases?
Q64100171The Impact of Childhood Obesity on Skeletal Health and Development
Q39053304The Impact of Fat and Obesity on Bone Microarchitecture and Strength in Children
Q38998176The endocrine manifestations of anorexia nervosa: mechanisms and management
Q38074897The pathogenesis, treatment and prevention of osteoporosis in men.
Q48072729The practical management of testosterone deficiency in men.
Q34633879Tissue physiology and pathology of aromatase
Q34910746UGT2B17 copy number gain in a large ankylosing spondylitis multiplex family
Q47268165Vertebral Volumetric Bone Density and Strength Are Impaired in Women With Low-Weight and Atypical Anorexia Nervosa