Close association between HER-2 amplification and overexpression in human tumors of non-breast origin

scientific article published on 01 February 2007

Close association between HER-2 amplification and overexpression in human tumors of non-breast origin is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1019380982
P356DOI10.1038/MODPATHOL.3800729
P698PubMed publication ID17361205

P50authorRonald SimonQ40046025
Luigi TornilloQ40856429
P2093author name stringLuigi Terracciano
Guido Sauter
Alessandro Lugli
Coya Tapia
Christian A Seemayer
Katharina Glatz
Martina Mirlacher
Hedvika Novotny
Hanspeter Spichtin
Milo Horcic
P2860cites workA subset of pancreatic adenocarcinomas demonstrates coamplification of topoisomerase IIalpha and HER2/neu: use of immunolabeling and multicolor FISH for potential patient screening andtreatmentQ81511454
Trastuzumab trials steal show at ASCO meetingQ81852806
Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogeneQ27860693
Tissue microarrays for high-throughput molecular profiling of tumor specimensQ29618675
ERBB receptors and cancer: the complexity of targeted inhibitorsQ29619520
The HER-2/neu oncogene in tumors of the gastrointestinal tractQ34311106
Trastuzumab: hopes and realitiesQ34569899
Tissue microarrays in drug discoveryQ35600009
The ErbB receptors and their ligands in cancer: an overview.Q36108987
Antitumor activity of HER-2 inhibitorsQ36211044
Trastuzumab plus docetaxel in HER-2/neu-positive prostate carcinoma: final results from the California Cancer Consortium Screening and Phase II TrialQ38447818
Evaluation of HER-2/neu oncogene status in breast tumors on tissue microarraysQ38452406
Strong correlation between results of fluorescent in situ hybridization and immunohistochemistry for the assessment of the ERBB2 (HER-2/neu) gene status in breast carcinomaQ38463184
Assessment of methods for tissue-based detection of the HER-2/neu alteration in human breast cancer: a direct comparison of fluorescence in situ hybridization and immunohistochemistryQ38463502
HER-2/neu gene amplification status in prostate cancer by fluorescence in situ hybridizationQ38474353
Her-2/neu oncogene amplification in clinically localised prostate cancerQ42252556
Prognostic factors and c-erbB-2 expression in non-small-cell lung carcinoma (c-erbB-2 in non-small cell lung carcinoma).Q43888317
HER2/neu gene amplification and protein overexpression in G3 pT2 transitional cell carcinoma of the bladder: a role for anti-HER2 therapy?Q44700955
Protein overexpression and gene amplification of HER-2 and EGFR in colorectal cancers: an immunohistochemical and fluorescent in situ hybridization studyQ47604705
HER2 amplification ratios by fluorescence in situ hybridization and correlation with immunohistochemistry in a cohort of 6556 breast cancer tissuesQ47612892
Assessment of HER‐2/neu overexpression and/or gene amplification in breast carcinomas: should in situ hybridization be the method of choice?Q47906737
Safety of treatment of metastatic breast cancer with trastuzumab beyond disease progressionQ47951353
Lack of trastuzumab activity in nonsmall cell lung carcinoma with overexpression of erb-B2: 39810: a phase II trial of Cancer and Leukemia Group B.Q50775865
Overexpression of her-2/neu in human prostate cancer and benign hyperplasiaQ58325256
Polysomy 17 in HER-2/neu Status Elaboration in Breast Cancer: Effect on Daily PracticeQ59567752
Comparison of fluorescence in situ hybridization and immunohistochemistry for the evaluation of HER-2/neu in breast cancerQ73181572
Relevance of p185 HER-2/neu oncoprotein quantification in human primary breast carcinomaQ73243706
Expression of the tyrosine kinase activity growth factor receptors (EGFR, ERB B2, ERB B3) in colorectal adenocarcinomas and adenomasQ73473432
Herceptin in patients with advanced or metastatic salivary gland carcinomas. A phase II studyQ73783125
Status of c-erbB-2 in gastric adenocarcinoma: a comparative study of immunohistochemistry, fluorescence in situ hybridization and enzyme-linked immuno-sorbent assayQ77925384
Prognostic relevance of gene amplifications and coamplifications in breast cancerQ81085059
Evaluation of clinical outcomes according to HER2 detection by fluorescence in situ hybridization in women with metastatic breast cancer treated with trastuzumabQ81151636
P433issue2
P304page(s)192-198
P577publication date2007-02-01
P1433published inModern PathologyQ15724578
P1476titleClose association between HER-2 amplification and overexpression in human tumors of non-breast origin
P478volume20

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cites work (P2860)
Q54594739Assessment of ErbB2 (Her2) in oesophageal adenocarcinomas: summary of a revised immunohistochemical evaluation system, bright field double in situ hybridisation and fluorescence in situ hybridisation.
Q35399306Biomarkers and molecular diagnosis of gastrointestinal and pancreatic neoplasms
Q43635123Continuous tissue microarray based identification of cancers with homogeneous target expression for successful targeted therapy in clinical routine practice
Q40886552Determination of Tumor Heterogeneity in Colorectal Cancers Using Heterogeneity Tissue Microarrays
Q35125725Epidermal growth factor receptor expression in urinary bladder cancer
Q28728860Fast and non-toxic in situ hybridization without blocking of repetitive sequences
Q33925506Gli1 promotes cell survival and is predictive of a poor outcome in ERalpha-negative breast cancer
Q35495307HER-2 Evaluation in a Specific Gastric Cancer Population with the Highest Rate of Mortality in Spain
Q37590066HER-2/neu Marker Examination using Immunohistochemical Method in Patients Suffering from Gastric Adenocarcinoma
Q42431264HER2 diagnostics in gastric cancer—guideline validation and development of standardized immunohistochemical testing
Q34324291HER2 in gastric cancer: a digital image analysis in pre-neoplastic, primary and metastatic lesions.
Q33517907HER2 overexpression and amplification is present in a subset of ovarian mucinous carcinomas and can be targeted with trastuzumab therapy
Q41880900HER2 status in gastro-oesophageal adenocarcinomas assessed by two rabbit monoclonal antibodies (SP3 and 4B5) and two in situ hybridization methods (FISH and SISH)
Q35670454Human epidermal growth factor receptor-2 gene amplification in gastric cancer using tissue microarray technology.
Q49646394Immunophenotypic profile of tumor buds in breast cancer.
Q61852873Involvement of HER-2/neu and metastasis-related proteins in the development of ileal neuroendocrine tumors
Q57181580Overexpression of Epidermal Growth Factor Receptor (EGFR) and HER-2 in Bladder Carcinoma and Its Association with Patients' Clinical Features
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