Toll-like receptors and innate immunity

scientific article published on 01 September 2006

Toll-like receptors and innate immunity is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1053284995
P356DOI10.1007/S00109-006-0084-Y
P698PubMed publication ID16924467

P2093author name stringSatoshi Uematsu
Shizuo Akira
P2860cites workMD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4Q22009943
A frameshift mutation in NOD2 associated with susceptibility to Crohn's diseaseQ22251291
The inflammasomeQ24276127
A Toll-like receptor recognizes bacterial DNAQ24290668
Discrimination of bacterial lipoproteins by Toll-like receptor 6Q24291383
CLAN, a novel human CED-4-like geneQ24291485
Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndromeQ24291856
RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systemsQ24292468
Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detectionQ24292675
Human TLR-7-, -8-, and -9-mediated induction of IFN-alpha/beta and -lambda Is IRAK-4 dependent and redundant for protective immunity to virusesQ24294677
Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunityQ24296473
Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3...Q24297037
CATERPILLER: a novel gene family important in immunity, cell death, and diseasesQ24298131
Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signalingQ37585525
Toll-like receptor 9 signaling activates NF-kappaB through IFN regulatory factor-8/IFN consensus sequence binding protein in dendritic cellsQ38340967
The roles of Toll-like receptor 9, MyD88, and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsetsQ38356908
Hemagglutinin protein of wild-type measles virus activates toll-like receptor 2 signalingQ39686635
Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen productionQ40409755
Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} inductionQ40446857
Host susceptibility and clinical outcomes in toll-like receptor 5-deficient patients with typhoid fever in VietnamQ40513723
Separation and structural analysis of lipoprotein in a lipopolysaccharide preparation from Porphyromonas gingivalisQ40523007
TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta inductionQ40675827
Genomic DNA released by dying cells induces the maturation of APCsQ40785552
Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoinQ41912941
Interferon-alpha and interleukin-12 are induced differentially by Toll-like receptor 7 ligands in human blood dendritic cell subsetsQ42079485
Cutting edge: CATERPILLER: a large family of mammalian genes containing CARD, pyrin, nucleotide-binding, and leucine-rich repeat domainsQ44172193
Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9.Q45710766
Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virusQ45739890
Birc1e is the gene within the Lgn1 locus associated with resistance to Legionella pneumophilaQ48269403
Toll receptor families: structure and function.Q52643048
A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA.Q54631516
TLR9-Dependent Recognition of MCMV by IPC and DC Generates Coordinated Cytokine Responses that Activate Antiviral NK Cell FunctionQ56998126
Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genesQ77137033
Unresponsiveness of MyD88-deficient mice to endotoxinQ78093558
Impaired thymic development in mouse embryos deficient in apoptotic DNA degradationQ78782078
The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infectionQ82412798
Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteinsQ24300005
Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMOQ24303248
The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-betaQ24305136
Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8Q24310398
Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)Q24317711
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon inductionQ24318426
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virusQ24336255
The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMOQ24336822
De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseasesQ24337040
Heterotypic interactions among NACHT domains: implications for regulation of innate immune responsesQ24337800
Innate immune recognition of viral infectionQ24498364
mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive propertiesQ24530264
The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoterQ24558779
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infectionQ24633526
Toll-like receptorsQ27860671
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responsesQ27860685
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3Q27860854
Pathogen recognition and innate immunityQ27861084
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3Q27861127
Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6Q28115232
Gout-associated uric acid crystals activate the NALP3 inflammasomeQ28131797
VISA is an adapter protein required for virus-triggered IFN-beta signalingQ28131814
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5Q28185796
IKKepsilon and TBK1 are essential components of the IRF3 signaling pathwayQ28190704
Triggering the interferon antiviral response through an IKK-related pathwayQ28191761
TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signalingQ28201815
Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's diseaseQ28201834
Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expressionQ28211358
Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathwayQ28216760
Evasion of Toll-like receptor 5 by flagellated bacteriaQ28256503
TLR11 activation of dendritic cells by a protozoan profilin-like protein.Q34414638
The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I.Q34457606
CARD15 mutations in Blau syndromeQ34517310
Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2.Q34858442
Recognition of pathogen-associated molecular patterns by TLR familyQ35044748
IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblastsQ35122228
Recognition of fungal pathogens by Toll-like receptorsQ35868185
Role of the Toll/interleukin-1 receptor signaling pathway in host resistance and pathogenesis during infection with protozoan parasites.Q35884180
Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitisQ36017935
The poxvirus protein A52R targets Toll-like receptor signaling complexes to suppress host defenseQ36370571
Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2.Q36370968
Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cellsQ36371359
A Common Dominant TLR5 Stop Codon Polymorphism Abolishes Flagellin Signaling and Is Associated with Susceptibility to Legionnaires' DiseaseQ36371497
The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infectionQ36402648
Differential requirement for TANK-binding kinase-1 in type I interferon responses to toll-like receptor activation and viral infectionQ36402672
Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulenceQ36403362
CATERPILLERs, pyrin and hereditary immunological disordersQ36405072
A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling.Q37421291
Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseasesQ28263484
Differential activation of the inflammasome by caspase-1 adaptors ASC and IpafQ28266417
Cutting edge: TNFR-associated factor (TRAF) 6 is essential for MyD88-dependent pathway but not toll/IL-1 receptor domain-containing adaptor-inducing IFN-beta (TRIF)-dependent pathway in TLR signalingQ28278006
The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adultsQ28289939
Cryopyrin activates the inflammasome in response to toxins and ATPQ28291313
Signalling pathways and molecular interactions of NOD1 and NOD2Q28298636
A toll-like receptor that prevents infection by uropathogenic bacteriaQ28504943
TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathwayQ28505835
Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall componentsQ28511151
The adaptor molecule TIRAP provides signalling specificity for Toll-like receptorsQ28511605
Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNAQ28513215
Activation of target-tissue immune-recognition molecules by double-stranded polynucleotidesQ28571397
Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNAQ28587147
Identification of Lps2 as a key transducer of MyD88-independent TIR signallingQ28587545
Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectinsQ28588506
Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient miceQ28589323
CD36 is a sensor of diacylglyceridesQ28591244
Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathwayQ28592087
CARD6 is a modulator of NF-kappa B activation by Nod1- and Cardiak-mediated pathwaysQ28592172
Dectin-1 is a major beta-glucan receptor on macrophagesQ28593983
Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signalingQ28646137
Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signalingQ29614206
Innate immunity: the virtues of a nonclonal system of recognitionQ29614428
Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitisQ29615108
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3Q29615598
Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunityQ29615913
Cell type-specific involvement of RIG-I in antiviral responseQ29615914
IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursorsQ29618425
An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acidQ29620015
Involvement of toll-like receptor 4 in innate immunity to respiratory syncytial virusQ33848810
Murine retroviruses activate B cells via interaction with toll-like receptor 4Q34013073
Does the shape of lipid A determine the interaction of LPS with Toll-like receptors?Q34115875
Overexpression of Helicard, a CARD-containing helicase cleaved during apoptosis, accelerates DNA degradationQ34128741
Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4.Q34160547
TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta.Q34266420
RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activationQ34311133
P433issue9
P304page(s)712-725
P577publication date2006-09-01
P1433published inJournal of Molecular MedicineQ6295593
P1476titleToll-like receptors and innate immunity
P478volume84

Reverse relations

cites work (P2860)
Q33488110A dynamic network of transcription in LPS-treated human subjects
Q38857831A functional C-terminal TRAF3-binding site in MAVS participates in positive and negative regulation of the IFN antiviral response
Q37222176A novel TLR7 agonist reverses NK cell anergy and cures RMA-S lymphoma-bearing mice
Q37235428Activation and regulation of the pattern recognition receptors in obesity-induced adipose tissue inflammation and insulin resistance
Q37164687Amelioration in wound healing in diabetic toll-like receptor-4 knockout mice
Q37081654An essential role for the antiviral endoribonuclease, RNase-L, in antibacterial immunity.
Q34431983An intranasally delivered Toll-like receptor 7 agonist elicits robust systemic and mucosal responses to Norwalk virus-like particles
Q37633698Antiviral autophagy restrictsRift Valley fever virus infection and is conserved from flies to mammals
Q42169591Autophagy is an essential component of Drosophila immunity against vesicular stomatitis virus
Q37093017B cell autonomous TLR signaling and autoimmunity
Q38042414Beta-glucan: an ideal immunostimulant in aquaculture (a review).
Q33903361Calcineurin inactivation leads to decreased responsiveness to LPS in macrophages and dendritic cells and protects against LPS-induced toxicity in vivo
Q41969861Candesartan inhibits Toll-like receptor expression and activity both in vitro and in vivo
Q34565532Characterization analysis and polymorphism detection of the porcine Myd88 gene
Q37075540Characterization of promoter sequence of toll-like receptor genes in Vechur cattle
Q59355447Cloning and Characterization of Two Toll Receptors ( and ) in Response to White Spot Syndrome Virus in the Red Swamp Crayfish
Q51563069Co-ordinated regulation of plasmacytoid dendritic cell surface receptors upon stimulation with herpes simplex virus type 1.
Q38259666Cross-talk between HPA-axis-increased glucocorticoids and mitochondrial stress determines immune responses and clinical manifestations of patients with sepsis.
Q27640796Crystal structure of the Nod1 caspase activation and recruitment domain
Q47146788Danger of frustrated sensors: Role of Toll-like receptors and NOD-like receptors in aseptic and septic inflammations around total hip replacements
Q34889330Decreased dengue replication and an increased anti-viral humoral response with the use of combined Toll-like receptor 3 and 7/8 agonists in macaques
Q33937994Demonstration of increased toll-like receptor 2 and toll-like receptor 4 expression in monocytes of type 1 diabetes mellitus patients with microvascular complications
Q37125939Determination of T-cell fate by dendritic cells
Q33693974Diabetes is a proinflammatory state: a translational perspective
Q37130691Differential effects of the CpG-Toll-like receptor 9 axis on pregnancy outcome in nonobese diabetic mice and wild-type controls
Q84963988Differential induction of Toll-like receptor gene expression in equine monocytes activated by Toll-like receptor ligands or TNF-α
Q34158278Distinct inflammatory signals have physiologically divergent effects on epigenetic regulation of Foxp3 expression and Treg function.
Q38613932Dual Role of p53 in Innate Antiviral Immunity
Q33745427Dysregulation of p38 and MKP-1 in response to NOD1/TLR4 stimulation in sarcoid bronchoalveolar cells
Q89529434Effects of 1,25-dihydroxyvitamin D3 on the Inflammatory Responses of Stromal Vascular Cells and Adipocytes from Lean and Obese Mice
Q53565092Effects of low-protein diets supplemented with indispensable amino acids on growth performance, intestinal morphology and immunological parameters in 13 to 35 kg pigs.
Q28917161Elimination of the unnecessary: intra- and extracellular signaling by anionic phospholipids
Q30300333Emerging therapeutic targets of sepsis-associated acute kidney injury
Q34449865Eritoran: the evidence of its therapeutic potential in sepsis
Q37448034Fatty acids modulate Toll-like receptor 4 activation through regulation of receptor dimerization and recruitment into lipid rafts in a reactive oxygen species-dependent manner
Q36875513Fine-tuning of the innate immune response by microRNAs.
Q36311828Frequency of TLR 2, 4, and 9 gene polymorphisms in Chinese population and their susceptibility to type 2 diabetes and coronary artery disease
Q37671802Functional genomics of silencing TREM-1 on TLR4 signaling in macrophages
Q36178531Gene Expression Profiling of Pulmonary Artery in a Rabbit Model of Pulmonary Thromboembolism
Q37172163Genetic variation and atherosclerosis
Q36440629Glial toll-like receptor signaling in central nervous system infection and autoimmunity
Q58762557Global Long Noncoding RNA and mRNA Expression Changes between Prenatal and Neonatal Lung Tissue in Pigs
Q36943779High glucose induces toll-like receptor expression in human monocytes: mechanism of activation
Q37280787How can calcium pyrophosphate crystals induce inflammation in hypophosphatasia or chronic inflammatory joint diseases?
Q36157687Human formyl peptide receptor 2 senses highly pathogenic Staphylococcus aureus
Q37075445Humoral immunity against capsule polysaccharide protects the host from magA+ Klebsiella pneumoniae-induced lethal disease by evading Toll-like receptor 4 signaling
Q36710627Identification of genes particularly sensitive to lipopolysaccharide (LPS) in human monocytes induced by wild-type versus LPS-deficient Neisseria meningitidis strains
Q94589870Imiquimod suppresses respiratory syncytial virus (RSV) replication via PKA pathway and reduces RSV induced-inflammation and viral load in mice lungs
Q55254424Immune Ecosystem of Virus-Infected Host Tissues.
Q37460790Immune influence on adult neural stem cell regulation and function
Q37040501Immune responses to malignancies
Q37129925Increased TLR4 expression in murine placentas after oral infection with periodontal pathogens
Q37408117Increased secretion of IP-10 from monocytes under hyperglycemia is via the TLR2 and TLR4 pathway
Q36459935Increased toll-like receptor (TLR) 2 and TLR4 expression in monocytes from patients with type 1 diabetes: further evidence of a proinflammatory state
Q33300685Induction of TNF-alpha by LPS in Schwann cell is regulated by MAPK activation signals.
Q89450344Induction of inducible nitric oxide synthase (iNOS) in Porphyromonas gingivalis LPS-treated mouse macrophage cell line (RAW264.7) requires Toll-like receptor 9
Q37987473Inflammation, atherosclerosis, and psoriasis.
Q36975932Innate immunity in inflammatory bowel disease.
Q34319249Intracellular immunity: finding the enemy within--how cells recognize and respond to intracellular pathogens
Q28265676Intracellular innate immunity in gouty arthritis: role of NALP3 inflammasome
Q26997316Intracellular nucleic acid sensors and autoimmunity
Q42273902Investigation of the role of endosomal Toll-like receptors in murine collagen-induced arthritis reveals a potential role for TLR7 in disease maintenance
Q41821136LPS-induced IL-6, IL-8, VCAM-1, and ICAM-1 expression in human lymphatic endothelium
Q37136127Lipopolysaccharide sensing an important factor in the innate immune response to Gram-negative bacterial infections: benefits and hazards of LPS hypersensitivity
Q98172163Loss of Function Genetic Screen Identifies ATM Kinase as a Positive Regulator of TLR3-Mediated NF-κB Activation
Q24316163MDA5 is SUMOylated by PIAS2β in the upregulation of type I interferon signaling
Q38073753Macrophages, inflammation, and tumor suppressors: ARF, a new player in the game
Q36808165Mast cell-dependent anorexia and hypothermia induced by mucosal activation of Toll-like receptor 7
Q35886583Mechanisms and pathways of innate immune activation and regulation in health and cancer
Q34449816Mechanisms of fever production and lysis: lessons from experimental LPS fever
Q58728893Modulation of three key innate immune pathways for the most common retinal degenerative diseases
Q46409074Molecular characterisation of Toll-like receptors in the black flying fox Pteropus alecto.
Q38611714Multicolor flow cytometric analysis of TLR2 and TLR9 expression and function in NK cells from patients with ANCA-associated vasculitis.
Q40260971Myocardial expression of Toll-like receptor 4 predicts the response to immunosuppressive therapy in patients with virus-negative chronic inflammatory cardiomyopathy
Q42573172Neonatal innate immunity and Toll-like receptor
Q34309219Network analysis identifies a putative role for the PPAR and type 1 interferon pathways in glucocorticoid actions in asthmatics
Q36655897Nod-like proteins in immunity, inflammation and disease
Q35173250Nonimmune Cells Contribute to Crosstalk between Immune Cells and Inflammatory Mediators in the Innate Response to Trypanosoma cruzi Infection
Q27022826Nonprofessional phagocytic cell receptors involved in Staphylococcus aureus internalization
Q53268885Oligodeoxynucleotide inhibition of Toll-like receptors 3, 7, 8, and 9 suppresses cytokine production in a human rheumatoid arthritis model.
Q34095777Oxygen-glucose deprivation of neurons transfected with toll-like receptor 3-siRNA: Determination of an optimal transfection sequence.
Q31001219PLP2 of mouse hepatitis virus A59 (MHV-A59) targets TBK1 to negatively regulate cellular type I interferon signaling pathway
Q39924024PLP2, a potent deubiquitinase from murine hepatitis virus, strongly inhibits cellular type I interferon production
Q39659848Peptidoglycan derived from Staphylococcus epidermidis induces Connexin43 hemichannel activity with consequences on the innate immune response in endothelial cells
Q37281187Pioglitazone inhibits Toll-like receptor expression and activity in human monocytes and db/db mice
Q35071279Placental TNF-α signaling in illness-induced complications of pregnancy
Q38353384PolyI:C-induced reduction in uptake of soluble antigen is independent of dendritic cell activation
Q43959782Polymorphism in 3′‐untranslated region of toll‐like receptor 4 gene is associated with protection from hepatitis B virus recurrence after liver transplantation
Q87105804Probiotic-Induced Priming of Innate Immunity to Protect Against Rotaviral Infection
Q35003734Regulation of toll-like receptor 1 and -2 in neonatal mice brains after hypoxia-ischemia
Q48277809Role of TLR4 and miR-155 in peripheral blood mononuclear cell-mediated inflammatory reaction in coronary slow flow and coronary arteriosclerosis patients.
Q38237647Role of Th17 Cells in the Pathogenesis of Human IBD.
Q50072073Salmonella-induced SipB-independent cell death requires Toll-like receptor-4 signalling via the adapter proteins Tram and Trif
Q37549926Sensors of the innate immune system: their mode of action
Q26853544Sepsis-induced Cardiac Mitochondrial Damage and Potential Therapeutic Interventions in the Elderly
Q38290813Single-stranded oligonucleotides can inhibit cytokine production induced by human toll-like receptor 3.
Q33323372Sub-nucleocapsid nanoparticles: a nasal vaccine against respiratory syncytial virus
Q39933420Suppressed production of pro-inflammatory cytokines by LPS-activated macrophages after treatment with Toxoplasma gondii lysate
Q41943483Surface expression of Toll-like receptor 9 is upregulated on intestinal epithelial cells in response to pathogenic bacterial DNA.
Q37152614TLR-3 receptor activation protects the very immature brain from ischemic injury
Q36654413TLR2 enhances ovarian cancer stem cell self-renewal and promotes tumor repair and recurrence
Q39947429TLR2 expression and signaling-dependent inflammation impair wound healing in diabetic mice
Q90335945TLR4-RelA-miR-30a signal pathway regulates Th17 differentiation during experimental autoimmune encephalomyelitis development
Q37447389TLR9 activation coupled to IL-10 deficiency induces adverse pregnancy outcomes
Q38133632Tackling the physiological barriers for successful mesenchymal stem cell transplantation into the central nervous system.
Q92024962Targeting innate sensing in the tumor microenvironment to improve immunotherapy
Q33707052The Association of OASL and Type I Interferons in the Pathogenesis and Survival of Intracellular Replicating Bacterial Species
Q43097032The K5 capsule of Escherichia coli strain Nissle 1917 is important in mediating interactions with intestinal epithelial cells and chemokine induction
Q83401137The Role of Toll-Like Receptors in Diabetes-Induced Inflammation: Implications for Vascular Complications
Q37728656The TLR7 agonists imiquimod and gardiquimod improve DC-based immunotherapy for melanoma in mice
Q42396872The activation of CD14, TLR4, and TLR2 by mmLDL induces IL-1β, IL-6, and IL-10 secretion in human monocytes and macrophages
Q34491598The airway epithelium: soldier in the fight against respiratory viruses
Q31171481The effect of TLR9 agonist CpG oligodeoxynucleotides on the intestinal immune response of cobia (Rachycentron canadum).
Q81077941The expression of E-selectin and chemokines in the cultured human lymphatic endothelium with lipopolysaccharides
Q34553478The expression of Toll-like receptors and development of severe sepsis in patients with acute myeloid leukemias after induction chemotherapy
Q27481673The response of mammalian cells to double-stranded RNA
Q39105949The role of toll-like receptors (TLRs) in urinary tract infections (UTIs).
Q64058653Toll-Like Receptor 9 Plays a Pivotal Role in Angiotensin II-Induced Atherosclerosis
Q59800406Toll-Like Receptor and miRNA-let-7e Expression Alter the Inflammatory Response in Leishmania amazonensis-Infected Macrophages
Q37268889Toll-like receptor 2 mediates microglia/brain macrophage MT1-MMP expression and glioma expansion
Q33830986Toll-like receptor 4 (TLR4) expression in human and murine pancreatic beta-cells affects cell viability and insulin homeostasis
Q36235562Toll-like receptor 4 mediates intrauterine growth restriction after systemic Campylobacter rectus infection in mice.
Q33588560Toll-like receptor 4 promoter polymorphisms: common TLR4 variants may protect against severe urinary tract infection
Q33920072Toll-like receptor 9 polymorphisms influence mother-to-child transmission of human immunodeficiency virus type 1.
Q56336950Toll-like receptor agonist R848 blocks Zika virus replication by inducing the antiviral protein viperin
Q39796172Toll-like receptor agonists induce inflammation and cell death in a model of head and neck squamous cell carcinomas
Q37186819Toll-like receptor signalling on Tregs: to suppress or not to suppress?
Q37023459Toll-like receptors and cytokines as surrogate biomarkers for evaluating vaginal immune response following microbicide administration
Q53687316Toll-like receptors in immunity and inflammatory diseases: Past, present, and future.
Q34664161Toll-like receptors modulate adult hippocampal neurogenesis
Q27486231Toll-like receptors regulation of viral infection and disease☆
Q38586199Toll-like receptors-2 and 4 are overexpressed in an experimental model of particle-induced osteolysis
Q37420851Transcriptional profiling of hilar nodes from pigs after experimental infection with Actinobacillus pleuropneumoniae
Q92700295Transcriptome Modifications in Porcine Adipocytes via Toll-Like Receptors Activation
Q42428099Two overlapping domains of a lyssavirus matrix protein that acts on different cell death pathways
Q59352585Type III Interferons in Antiviral Defenses at Barrier Surfaces
Q34786031Ubiquitination of ECSIT is crucial for the activation of p65/p50 NF-κBs in Toll-like receptor 4 signaling
Q36169566Uncovering the Complex Transcriptome Response of Mytilus chilensis against Saxitoxin: Implications of Harmful Algal Blooms on Mussel Populations
Q64298677Urinary tract infections (UTIs) or genital tract infections (GTIs)? It's the diagnostics that count
Q39371774Virus recognition by Toll-7 activates antiviral autophagy in Drosophila
Q47338478ZikaBase: An integrated ZIKV- Human Interactome Map database
Q34223531p21Cip restrains hippocampal neurogenesis and protects neuronal progenitors from apoptosis during acute systemic inflammation