Duodenal-content reflux into the esophagus leads to expression of Cdx2 and Muc2 in areas of squamous epithelium in rats

scientific article published on 01 July 2007

Duodenal-content reflux into the esophagus leads to expression of Cdx2 and Muc2 in areas of squamous epithelium in rats is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S11605-007-0162-7
P698PubMed publication ID17440788

P2093author name stringRichard Poulsom
Manuel Pera
Antonio Cardesa
Luis Grande
Miguel Pera
Antonio Palacín
Maria J Brito
Carmen de Bolós
P2860cites workCdx2 as a Marker of Epithelial Intestinal Differentiation in the EsophagusQ30311906
Molecular evolution of the metaplasia-dysplasia-adenocarcinoma sequence in the esophagusQ33611018
An intestine-specific homeobox gene regulates proliferation and differentiationQ34370444
Clinical practice. Barrett's EsophagusQ34563466
Experimental Barrett's esophagus and the origin of intestinal metaplasiaQ34569483
Stem cells of the oesophageal epitheliumQ34603090
The homeodomain protein CDX2 is an early marker of Barrett's oesophagus.Q35588064
The role of Cdx proteins in intestinal development and cancerQ35770120
Barrett's esophagus: a molecular perspectiveQ36137465
A study of regional gut endoderm potency by analysis of Cdx2 null mutant chimaeric miceQ38484917
Reflux of duodenal or gastro-duodenal contents induces esophageal carcinoma in ratsQ39255662
Cdx1 and cdx2 expression during intestinal developmentQ40847809
Molecular characterization of the large heavily glycosylated domain glycopeptide from the rat small intestinal Muc2 mucin.Q41161468
Duodenal content reflux esophagitis in the rat: an animal model for the ulcer-associated cell lineage (UACL)?Q41830933
Chronic acid exposure leads to activation of the cdx2 intestinal homeobox gene in a long-term culture of mouse esophageal keratinocytesQ42438360
Expression of Cdx2 in early GRCL of Barrett's esophagus induced in rats by duodenal refluxQ42476498
Phenotypic characteristics of a distinctive multilayered epithelium suggests that it is a precursor in the development of Barrett's esophagusQ42504051
CDX1 protein expression in normal, metaplastic, and neoplastic human alimentary tract epitheliumQ42798173
Bile acids directly augment caudal related homeobox gene Cdx2 expression in oesophageal keratinocytes in Barrett's epitheliumQ42844302
Influence of esophagojejunostomy on the induction of adenocarcinoma of the distal esophagus in Sprague-Dawley rats by subcutaneous injection of 2,6-dimethylnitrosomorpholineQ44045047
Cdx2 ectopic expression induces gastric intestinal metaplasia in transgenic mice.Q50501238
Expression of intestine-specific transcription factors, CDX1 and CDX2, in intestinal metaplasia and gastric carcinomas.Q53384678
Duodenal-content reflux esophagitis induces the development of glandular metaplasia and adenosquamous carcinoma in rats.Q53407603
Detection by scanning electron microscopy of a distinctive esophageal surface cell at the junction of squamous and Barrett's epitheliumQ70530852
Homeodomain protein CDX2 regulates goblet-specific MUC2 gene expressionQ78862429
Aberrant expression of CDX2 in Barrett's epithelium and inflammatory esophageal mucosaQ78865239
Esophagitis produced by reflux of duodenal contents in ratsQ78983561
Phenotype of columnar-lined esophagus in rats with esophagogastroduodenal anastomosis: similarity to human Barrett's esophagusQ79954808
The role of overdiagnosis and reclassification in the marked increase of esophageal adenocarcinoma incidenceQ81290009
P433issue7
P304page(s)869-874
P577publication date2007-07-01
P1433published inJournal of Gastrointestinal SurgeryQ15764393
P1476titleDuodenal-content reflux into the esophagus leads to expression of Cdx2 and Muc2 in areas of squamous epithelium in rats
P478volume11

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cites work (P2860)
Q33987356Acid and bile salt-induced CDX2 expression differs in esophageal squamous cells from patients with and without Barrett's esophagus
Q82468769Activation of the BMP4 pathway and early expression of CDX2 characterize non-specialized columnar metaplasia in a human model of Barrett's esophagus
Q48233200Aspirin prevents NF-κB activation and CDX2 expression stimulated by acid and bile salts in oesophageal squamous cells of patients with Barrett's oesophagus.
Q37762151Barrett esophagus: an update
Q54290278Barrett's oesophagus
Q40671403Bile acid and inflammation activate gastric cardia stem cells in a mouse model of Barrett-like metaplasia.
Q39433403CDX2 hox gene product in a rat model of esophageal cancer
Q37809363Cdx genes, inflammation, and the pathogenesis of intestinal metaplasia
Q33384875Deoxycholic acid induces the overexpression of intestinal mucin, MUC2, via NF-kB signaling pathway in human esophageal adenocarcinoma cells
Q33873724Ectopic Cdx2 expression in murine esophagus models an intermediate stage in the emergence of Barrett's esophagus
Q33786336History, molecular mechanisms, and endoscopic treatment of Barrett's esophagus
Q37809354Molecular Determinants of Metaplastic and Neoplastic Transformation in the Esophageal Epithelium
Q39268802Reflux esophagitis and its role in the pathogenesis of Barrett's metaplasia
Q36841300Relationships of CDXs and apical sodium-dependent bile acid transporter in Barrett's esophagus
Q54372521Role of Th-2 cytokines in the development of Barrett's esophagus in rats.
Q46680892The effect of retinoic acid and deoxycholic acid on the differentiation of primary human esophageal keratinocytes.

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