Janus kinase mutations in the development of acute megakaryoblastic leukemia in children with and without Down's syndrome

scientific article published on 19 April 2007

Janus kinase mutations in the development of acute megakaryoblastic leukemia in children with and without Down's syndrome is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1026731729
P356DOI10.1038/SJ.LEU.2404694
P698PubMed publication ID17443226

P50authorHenrik HasleQ40506155
Jan-Henning KlusmannQ42231158
P2093author name stringCreutzig U
Kaspers GJ
Zwaan CM
Reinhardt D
van den Heuvel-Eibrink MM
Hahlen K
P2860cites workPattern of malignant disorders in individuals with Down's syndrome.Q34571958
JAK2T875N is a novel activating mutation that results in myeloproliferative disease with features of megakaryoblastic leukemia in a murine bone marrow transplantation modelQ35849213
Activating alleles of JAK3 in acute megakaryoblastic leukemiaQ40255542
Mutations in KIT and RAS are frequent events in pediatric core-binding factor acute myeloid leukemiaQ40405651
AML patients with Down syndrome have a high cure rate with AML-BFM therapy with reduced dose intensityQ46513852
An inherited mutation leading to production of only the short isoform of GATA-1 is associated with impaired erythropoiesisQ55670499
JAK3 mutations occur in acute megakaryoblastic leukemia both in Down syndrome children and non-Down syndrome adultsQ79657116
Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1Q81749163
P433issue7
P921main subjectacute megakaryoblastic leukemiaQ4677933
P304page(s)1584-1587
P577publication date2007-04-19
P1433published inLeukemiaQ6534498
P1476titleJanus kinase mutations in the development of acute megakaryoblastic leukemia in children with and without Down's syndrome
P478volume21