Immunohistochemical staining of hMLH1 and hMSH2 reflects microsatellite instability status in ovarian carcinoma

scientific article published on 25 August 2006

Immunohistochemical staining of hMLH1 and hMSH2 reflects microsatellite instability status in ovarian carcinoma is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1043671835
P356DOI10.1038/MODPATHOL.3800672
P698PubMed publication ID16941012

P2093author name stringJinsong Liu
Rajyalakshmi Luthra
Daniel G Rosen
Kathy Q Cai
P2860cites workGenomic structure of human mismatch repair gene, hMLH1, and its mutation analysis in patients with hereditary non-polyposis colorectal cancer (HNPCC)Q48075190
Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancerQ48084125
Immunohistochemical detection of mismatch repair gene proteins as a useful tool for the identification of colorectal carcinoma with the mutator phenotype.Q53407311
Frameshift mutator mutationsQ57978058
Microsatellite instability, MLH-1 promoter hypermethylation, and frameshift mutations at coding mononucleotide repeat microsatellites in ovarian tumorsQ59123143
Microsatellite instability and alterations in the hMSH2 gene in human ovarian cancerQ70870193
Immunohistochemistry for hMLH1 and hMSH2: a practical test for DNA mismatch repair-deficient tumorsQ73090406
Immunohistochemical pattern of hMSH2/hMLH1 in familial and sporadic colorectal, gastric, endometrial and ovarian carcinomas with instability in microsatellite sequencesQ73526242
Microsatellite instability phenotype of tumors: genotyping or immunohistochemistry? The jury is still outQ77639588
Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumorsQ77639637
Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesisQ22122362
Mutations of two PMS homologues in hereditary nonpolyposis colon cancerQ24318484
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancerQ28256988
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancerQ28257360
Value of pedigree/clinical data, immunohistochemistry and microsatellite instability analyses in reducing the cost of determining hMLH1 and hMSH2 gene mutations in patients with colorectal cancerQ30588580
Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer).Q34557362
Microsatellite instability in ovarian neoplasmsQ36081495
Use of microsatellite instability and immunohistochemistry testing for the identification of individuals at risk for Lynch syndromeQ36246500
Extensive molecular screening for hereditary non-polyposis colorectal cancerQ36641429
Microsatellite instability differences between familial and sporadic ovarian cancersQ38353435
Choice of management strategy for colorectal cancer based on a diagnostic immunohistochemical test for defective mismatch repairQ42134566
Efficient detection of hereditary nonpolyposis colorectal cancer gene carriers by screening for tumor microsatellite instability before germline genetic testing.Q46001047
Microsatellite instability and alteration of the expression of hMLH1 and hMSH2 in ovarian clear cell carcinomaQ47616503
Validation of tissue microarray technology in ovarian carcinomaQ47791732
P433issue11
P921main subjectimmunohistochemistryQ899285
ovarian carcinomaQ18556145
P304page(s)1414-1420
P577publication date2006-08-25
P1433published inModern PathologyQ15724578
P1476titleImmunohistochemical staining of hMLH1 and hMSH2 reflects microsatellite instability status in ovarian carcinoma
P478volume19