Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, as first-line therapy in patients with metastatic breast cancer previously treated with anthracycline chemotherapy

scientific article published on 02 July 2007

Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, as first-line therapy in patients with metastatic breast cancer previously treated with anthracycline chemotherapy is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1200/JCO.2006.09.7535
P698PubMed publication ID17606972

P50authorLinda T VahdatQ40149511
P2093author name stringFrancesco Cognetti
Jean-Pierre Delord
Pierre Kerbrat
David Lebwohl
Henri Roché
Hervé Curé
Louise Yelle
Craig Bunnell
Louis Mauriac
Ronald Peck
Joseph Sparano
Rana Ezzeddine
P433issue23
P921main subjectphase II clinical trialQ42824440
ixabepiloneQ11711607
metastatic breast cancerQ12859063
P304page(s)3415-3420
P577publication date2007-07-02
P1433published inJournal of Clinical OncologyQ400292
P1476titlePhase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, as first-line therapy in patients with metastatic breast cancer previously treated with anthracycline chemotherapy
P478volume25

Reverse relations

cites work (P2860)
Q43152531A phase II clinical trial of ixabepilone (Ixempra; BMS-247550; NSC 710428), an epothilone B analog, in patients with metastatic renal cell carcinoma
Q37172818A phase II study of sagopilone (ZK 219477; ZK-EPO) in patients with breast cancer and brain metastases
Q33526311A phase II trial of the epothilone B analog ixabepilone (BMS-247550) in patients with metastatic melanoma
Q33387547A phase II trial of trastuzumab plus weekly ixabepilone and carboplatin in patients with HER2-positive metastatic breast cancer: an Eastern Cooperative Oncology Group Trial
Q36892821A randomized, phase II, three-arm study of two schedules of ixabepilone or paclitaxel plus bevacizumab as first-line therapy for metastatic breast cancer.
Q35975007Advancements in the Treatment of Metastatic Breast Cancer (MBC): The Role of Ixabepilone
Q35872691Advances in the management of metastatic breast cancer: options beyond first-line chemotherapy
Q89623255An Easy and Efficient Strategy for the Enhancement of Epothilone Production Mediated by TALE-TF and CRISPR/dcas9 Systems in Sorangium cellulosum
Q33999018Beyond taxanes: a review of novel agents that target mitotic tubulin and microtubules, kinases, and kinesins.
Q26865369Beyond taxanes: the next generation of microtubule-targeting agents
Q24633167Capecitabine monotherapy: review of studies in first-line HER-2-negative metastatic breast cancer
Q36245461Current approaches to the management of Her2-negative metastatic breast cancer
Q90554778Differential Morphological and Biochemical Recovery from Chemotherapy-Induced Peripheral Neuropathy Following Paclitaxel, Ixabepilone, or Eribulin Treatment in Mouse Sciatic Nerves
Q55407807Effects of transcriptional mode on promoter substitution and tandem engineering for the production of epothilones in Myxococcus xanthus.
Q35599745Eribulin mesylate as a microtubule inhibitor for treatment of patients with metastatic breast cancer
Q37067999Eribulin mesylate versus ixabepilone in patients with metastatic breast cancer: a randomized Phase II study comparing the incidence of peripheral neuropathy.
Q38555471Glucocorticoids and Cancer.
Q34611801Ixabepilone (ixempra), a therapeutic option for locally advanced or metastatic breast cancer.
Q37797749Ixabepilone Plus Capecitabine for Breast Cancer Patients With an Early Metastatic Relapse After Adjuvant Chemotherapy: Two Clinical Trials
Q28534786Ixabepilone administered weekly or every three weeks in HER2-negative metastatic breast cancer patients; a randomized non-comparative phase II trial
Q37356274Ixabepilone as monotherapy or in combination for the treatment of advanced breast cancer
Q34788890Ixabepilone as monotherapy or in combination with capecitabine for the treatment of advanced breast cancer
Q34417996Ixabepilone development across the breast cancer continuum: a paradigm shift
Q46173239Ixabepilone, mitoxantrone, and prednisone for metastatic castration-resistant prostate cancer after docetaxel-based therapy: a phase 2 study of the Department Of Defense Prostate Cancer Clinical Trials Consortium
Q34180965Ixabepilone-associated peripheral neuropathy: data from across the phase II and III clinical trials
Q34562783Ixabepilone-induced mitochondria and sensory axon loss in breast cancer patients
Q37290709Ixabepilone: a new chemotherapeutic option for refractory metastatic breast cancer
Q34418413Ixabepilone: a new treatment option for the management of taxane-resistant metastatic breast cancer
Q28298312Ixabepilone: a novel microtubule-stabilizing agent for the treatment of metastatic breast cancer
Q37563451Ixabepilone: in locally advanced or metastatic breast cancer
Q34289839Kinesins and cancer.
Q36714374Locoregional interaction of ixabepilone (ixempra) after breast cancer radiation
Q37403186Management of advanced breast cancer with the epothilone B analog, ixabepilone
Q37996079Medical therapy of endometrial cancer: current status and promising novel treatments.
Q30448951Neurological adverse effects caused by cytotoxic and targeted therapies.
Q37057994New therapeutic options for chemotherapy-resistant metastatic breast cancer: the epothilones.
Q37307168Novel combinations for the treatment of metastatic breast cancer
Q28279384Novel cytotoxic agents: epothilones
Q34611212Novel microtubule-targeting agents - the epothilones.
Q37321909Novel neurosensory testing in cancer patients treated with the epothilone B analog, ixabepilone
Q34636002Novel therapies for metastatic renal cell carcinoma: efforts to expand beyond the VEGF/mTOR signaling paradigm
Q34204598Optimizing ixabepilone treatment schedules in patients with advanced or metastatic breast cancer
Q37730282Phase I clinical, pharmacokinetic, and pharmacodynamic study of KOS-862 (Epothilone D) in patients with advanced solid tumors and lymphoma
Q37104791Phase I trial and pharmacokinetic study of ixabepilone administered daily for 5 days in children and adolescents with refractory solid tumors
Q36988082Phase I trial of ixabepilone administered as three oral doses each separated by 6 hours every 3 weeks in patients with advanced solid tumors
Q30433670Phase II clinical trial of ixabepilone in patients with recurrent or persistent platinum- and taxane-resistant ovarian or primary peritoneal cancer: a gynecologic oncology group study
Q34915389Phase II trial of ixabepilone administered daily for five days in children and young adults with refractory solid tumors: a report from the children's oncology group
Q34274925Present and future evolution of advanced breast cancer therapy
Q35847455Randomized Phase III Trial of Paclitaxel Once Per Week Compared With Nanoparticle Albumin-Bound Nab-Paclitaxel Once Per Week or Ixabepilone With Bevacizumab As First-Line Chemotherapy for Locally Recurrent or Metastatic Breast Cancer: CALGB 40502/NC
Q33990883Randomized phase III trial of ixabepilone plus capecitabine versus capecitabine in patients with metastatic breast cancer previously treated with an anthracycline and a taxane
Q36273796Recent Advances in the Development of Antineoplastic Agents Derived from Natural Products
Q35076330Synergistic activity of ixabepilone plus other anticancer agents: preclinical and clinical evidence
Q37791482The microtubule as a breast cancer target
Q36057858Treatment of Breast Cancer Brain Metastases
Q37707615Treatment options for advanced endometrial carcinoma
Q37207961Treatment options for breast cancer resistant to anthracycline and taxane
Q37350227Update on medication-induced peripheral neuropathy

Search more.