Transcriptional profiling after bile duct ligation identifies PAI-1 as a contributor to cholestatic injury in mice

scientific article published on 01 November 2005

Transcriptional profiling after bile duct ligation identifies PAI-1 as a contributor to cholestatic injury in mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/HEP.20903
P698PubMed publication ID16250054

P50authorRobert HeuckerothQ55098159
P2093author name stringYan Zhang
Hongtao Wang
Bhupinder P S Vohra
P2860cites workPlasminogen deficiency leads to impaired remodeling after a toxic injury to the liverQ24655869
The role of notch signaling in the development of intrahepatic bile ductsQ28296475
Plasminogen activators direct reorganization of the liver lobule after acute injuryQ28359705
Liver regenerationQ29614743
Plasminogen activator inhibitor-1 and the kidneyQ33960082
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Urokinase receptor (CD87) regulates leukocyte recruitment via beta 2 integrins in vivo.Q36401755
Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repairQ37357884
Pioglitazone prevents alcohol-induced fatty liver in rats through up-regulation of c-MetQ38344286
Limited role for CXC chemokines in the pathogenesis of alpha-naphthylisothiocyanate-induced liver injuryQ39736192
Cathepsin B inactivation attenuates hepatic injury and fibrosis during cholestasisQ39785797
Growth control of human biliary epithelial cells by interleukin 6, hepatocyte growth factor, transforming growth factor beta1, and activin A: comparison of a cholangiocarcinoma cell line with primary cultures of non-neoplastic biliary epithelial celQ40871475
Human intrahepatic biliary epithelial cells proliferate in vitro in response to human hepatocyte growth factorQ41020737
The urokinase-type plasminogen activator system in cancer metastasis: A reviewQ41522331
Bile duct ligation in rats induces biliary expression of cytokine-induced neutrophil chemoattractantQ41738693
Effects of human hepatocyte growth factor on the proliferation of human hepatocytes and hepatocellular carcinoma cell linesQ42467371
Angiotensin II increases plasminogen activator inhibitor type 1 and tissue-type plasminogen activator messenger RNA in cultured rat aortic smooth muscle cellsQ42495205
Inducible lung-specific urokinase expression reduces fibrosis and mortality after lung injury in miceQ44176958
Plasminogen activator-plasmin system potentiates the proliferation of hepatocytes in primary cultureQ44216178
Plasminogen directs the pleiotropic effects of uPA in liver injury and repairQ44216615
A single administration of adenoviral-mediated HGF cDNA permits survival of mice from acute hepatic failureQ44221104
Hepatocyte growth factor gene therapy of liver cirrhosis in ratsQ44406096
Inhibition of hypoxia/reoxygenation-induced oxidative stress in HGF-stimulated antiapoptotic signaling: role of PI3-K and Akt kinase upon rac1.Q44427665
Neutrophils aggravate acute liver injury during obstructive cholestasis in bile duct-ligated miceQ44527586
Functional importance of ICAM-1 in the mechanism of neutrophil-induced liver injury in bile duct-ligated miceQ44620832
Critical role of CXC chemokines in endotoxemic liver injury in miceQ44691593
Essential role for neutrophil recruitment to the liver in concanavalin A-induced hepatitisQ44701472
Liver cirrhosis is reverted by urokinase-type plasminogen activator gene therapyQ45873413
Selectin inhibition modulates Akt/MAPK signaling and chemokine expression after liver ischemia-reperfusionQ46375214
Urokinase receptor deficiency accelerates renal fibrosis in obstructive nephropathyQ47960094
PAI-1 deficiency attenuates the fibrogenic response to ureteral obstructionQ57741393
Mechanism of retarded liver regeneration in plasminogen activator-deficient mice: Impaired activation of hepatocyte growth factor after Fas-mediated massive hepatic apoptosisQ58883686
Hepatocyte growth factor promotes cell survival from fas-mediated cell death in hepatocellular carcinoma cells via Akt activation and Fas-death-inducing signaling complex suppressionQ72996740
Increased expression of plasminogen activator and plasminogen activator inhibitor during liver fibrogenesis of rats: role of stellate cellsQ73156216
Rapid activation of protein kinase B/Akt has a key role in antiapoptotic signaling during liver regenerationQ73405090
Angiotensin II induces PAI-1 expression through MAP kinase-dependent, but TGF beta and PI3 kinase-independent pathwayQ73618607
Type 1 plasminogen activator inhibitor deficiency aggravates the course of experimental glomerulonephritis through overactivation of transforming growth factor betaQ73745945
Acute obstructive cholangiopathy in interleukin-6 deficient mice: compensation by leukemia inhibitory factor (LIF) suggests importance of gp-130 signaling in the ductular reactionQ73880869
Anti-Fas induces hepatic chemokines and promotes inflammation by an NF-kappa B-independent, caspase-3-dependent pathwayQ74623251
Plasminogen activator inhibitor type-1 deficiency attenuates murine antigen-induced arthritisQ77749263
Hepatocyte growth factor signaling regulates transactivation of genes belonging to the plasminogen activation system via hypoxia inducible factor-1Q79185010
Plasminogen mediates liver regeneration and angiogenesis after experimental partial hepatectomyQ79249986
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)1099-1108
P577publication date2005-11-01
P1433published inHepatologyQ15724398
P1476titleTranscriptional profiling after bile duct ligation identifies PAI-1 as a contributor to cholestatic injury in mice
P478volume42

Reverse relations

cites work (P2860)
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