The use of Bcl-2 and PTHLH immunohistochemistry in the diagnosis of peripheral chondrosarcoma in a clinicopathological setting

scientific article published on 03 March 2005

The use of Bcl-2 and PTHLH immunohistochemistry in the diagnosis of peripheral chondrosarcoma in a clinicopathological setting is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00428-005-1208-4
P698PubMed publication ID15744499

P50authorJudith BovéeQ56949900
Pancras C.W. HogendoornQ58132916
P2093author name stringPaul H C Eilers
Liesbeth Hameetman
Anne-Marie Cleton-Jansen
Petra Kok
P2860cites workA direct interaction between EXT proteins and glycosyltransferases is defective in hereditary multiple exostosesQ22010746
Cloning of the putative tumour suppressor gene for hereditary multiple exostoses (EXT1)Q24308316
Bcl-2 lies downstream of parathyroid hormone-related peptide in a signaling pathway that regulates chondrocyte maturation during skeletal developmentQ24315654
EXT-mutation analysis and loss of heterozygosity in sporadic and hereditary osteochondromas and secondary chondrosarcomas.Q24540139
The EXT2 multiple exostoses gene defines a family of putative tumour suppressor genesQ28288396
Positional cloning of a gene involved in hereditary multiple exostosesQ28294904
PTH/PTHrP receptor in early development and Indian hedgehog-regulated bone growthQ28506149
Choosing among generalized linear models applied to medical dataQ32124490
Steroid hormone receptor expression and action in boneQ33829036
The estrogen receptor in the growth plate: implications for pubertal growthQ34523779
Paradoxical role of apoptosis in tumor progressionQ35014280
Role of Bcl-2 as a prognostic factor for survival in lung cancer: a systematic review of the literature with meta-analysisQ35167933
Parathyroid hormone-related Peptide expression in cartilaginous tumors.Q38455031
The Bcl-2 gene is differentially regulated by IL-2 and IL-4: role of the transcription factor NF-AT.Q41002850
Expression of estrogen receptor alpha and beta in the epiphyseal plate of the rat.Q52122950
Prognostic factors in chondrosarcoma of bone: a clinicopathologic analysis with emphasis on histologic gradingQ67652553
Steroid regulation of parathyroid hormone-related protein expression and action in the rat uterusQ71935923
Loss of heterozygosity and DNA ploidy point to a diverging genetic mechanism in the origin of peripheral and central chondrosarcomaQ73031248
Up-regulation of PTHrP and Bcl-2 expression characterizes the progression of osteochondroma towards peripheral chondrosarcoma and is a late event in central chondrosarcomaQ73351349
Cartilaginous tumors: fast contrast-enhanced MR imagingQ73441907
Expression of Indian hedgehog, parathyroid hormone-related protein, and their receptors in the postnatal growth plate of the rat: evidence for a locally acting growth restraining feedback loop after birthQ73858590
Co-expression of parathyroid hormone-related protein (PTHrP) and PTH/PTHrP receptor in cartilaginous tumours: a marker for malignancy?Q74091642
Expression of growth factors and their receptors in adamantinoma of long bones and the implication for its histogenesisQ74532030
PTHrP and Bcl-2: essential regulatory molecules in chondrocyte differentiation and chondrogenic tumorsQ74646731
BMP-6 is an autocrine stimulator of chondrocyte differentiationQ77421900
Transforming growth factor beta1 and recruitment of macrophages and mast cells in airways in chronic obstructive pulmonary diseaseQ77660840
Risk factors for local recurrence after breast-conserving therapy for invasive carcinomas: a case-control study of histological factors and alterations in oncogene expressionQ78222760
A new histologic approach to the differentiation of enchondroma and chondrosarcoma of the bones. A clinicopathologic analysis of 51 casesQ93645771
P433issue4
P921main subjectimmunohistochemistryQ899285
P304page(s)430-437
P577publication date2005-03-03
P1433published inVirchows ArchivQ19059548
P1476titleThe use of Bcl-2 and PTHLH immunohistochemistry in the diagnosis of peripheral chondrosarcoma in a clinicopathological setting
P478volume446

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cites work (P2860)
Q84522319Dedifferentiated peripheral chondrosarcomas: regulation of EXT-downstream molecules and differentiation-related genes
Q40451602Dysplasia epiphysealis hemimelica: a case report with novel pathophysiologic aspects
Q36212898Emerging pathways in the development of chondrosarcoma of bone and implications for targeted treatment
Q53070824Genetic alterations in chondrosarcomas - keys to targeted therapies?
Q33273451Markers aiding the diagnosis of chondroid tumors: an immunohistochemical study including osteonectin, bcl-2, cox-2, actin, calponin, D2-40 (podoplanin), mdm-2, CD117 (c-kit), and YKL-40.
Q41623377Mast cells density in fibrotic capsule of enchondroma and well-differentiated chondrosarcoma: a method for histopathologic differentiation.
Q21202906Multiple osteochondromas
Q34162459No haploinsufficiency but loss of heterozygosity for EXT in multiple osteochondromas
Q37185828Src kinases in chondrosarcoma chemoresistance and migration: dasatinib sensitises to doxorubicin in TP53 mutant cells
Q36817838Tissue microarrays analysis in chondrosarcomas: light microscopy, immunohistochemistry and xenograft study