[Therapeutic innovation in osteoporosis (antisclerostin antibody and denosumab)]

scientific article published on 01 October 2011

[Therapeutic innovation in osteoporosis (antisclerostin antibody and denosumab)] is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0003-4266(11)70005-1
P698PubMed publication ID22008272

P50authorOlivier ChabreQ72940457
P2093author name stringV Kerlan
M-A Quemerais-Durieu
P2860cites workEffect of denosumab on bone mineral density in women receiving adjuvant aromatase inhibitors for non-metastatic breast cancer: subgroup analyses of a phase 3 studyQ46077710
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Comparison of the effect of denosumab and alendronate on BMD and biochemical markers of bone turnover in postmenopausal women with low bone mass: a randomized, blinded, phase 3 trialQ46393065
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Inhibition of sclerostin by monoclonal antibody enhances bone healing and improves bone density and strength of nonfractured bonesQ84033150
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RANK is essential for osteoclast and lymph node developmentQ24598872
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Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostinQ28261537
Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: a novel mechanism for hormonal control of osteoblastogenesisQ28265821
Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strengthQ28274891
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Sclerostin antibody treatment increases bone formation, bone mass, and bone strength in a rat model of postmenopausal osteoporosisQ28302443
Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in miceQ28312170
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Serum sclerostin levels negatively correlate with parathyroid hormone levels and free estrogen index in postmenopausal womenQ33786865
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Osteoclast precursors, RANKL/RANK, and immunologyQ36324916
The role of the immune system in the pathophysiology of osteoporosisQ36324969
Functional variants within the secreted frizzled-related protein 3 gene are associated with hip osteoarthritis in females.Q36448809
Osteoporosis: now and the futureQ36564425
The many ways of Wnt in cancerQ36701583
Targeting the Wnt/beta-catenin pathway to regulate bone formation in the adult skeletonQ36774955
Activation of beta-catenin signaling in articular chondrocytes leads to osteoarthritis-like phenotype in adult beta-catenin conditional activation mice.Q37092804
Does osteocytic SOST suppression mediate PTH bone anabolism?Q37675392
Treatment of osteoporosis with denosumabQ37710822
Interleukin-1beta and tumor necrosis factor-alpha, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cellsQ40927574
Msx2 promotes cardiovascular calcification by activating paracrine Wnt signalsQ42717983
Effects of denosumab on bone histomorphometry: the FREEDOM and STAND studies.Q43038398
The effect of a single dose of osteoprotegerin in postmenopausal womenQ43520860
Effects of denosumab on bone mineral density and bone turnover in postmenopausal women transitioning from alendronate therapy.Q45931469
P304page(s)S15-22
P577publication date2011-10-01
P1433published inAnnales d'EndocrinologieQ15753551
P1476title[Therapeutic innovation in osteoporosis (antisclerostin antibody and denosumab)]
P478volume72 Suppl 1

Reverse relations

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