First drugs found to inhibit elusive cancer target

scientific article published on 07 November 2011

First drugs found to inhibit elusive cancer target is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/NM1111-1325
P953full work available at URLhttp://www.nature.com/articles/nm1111-1325
http://www.nature.com/articles/nm1111-1325.pdf
https://www.nature.com/articles/nm1111-1325.pdf
P698PubMed publication ID22064391

P2093author name stringMelinda Wenner Moyer
P2860cites workRNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemiaQ29617201
Selective inhibition of BET bromodomainsQ24301009
c-Myc regulates transcriptional pause releaseQ24629119
Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcriptionQ24672881
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemiaQ27674674
BET bromodomain inhibition as a therapeutic strategy to target c-MycQ28247024
Targeting MYC dependence in cancer by inhibiting BET bromodomainsQ29617196
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)1325
P577publication date2011-11-07
P1433published inNature medicineQ1633234
P1476titleFirst drugs found to inhibit elusive cancer target
P478volume17

Reverse relations

cites work (P2860)
Q42380933A fast, open source implementation of adaptive biasing potentials uncovers a ligand design strategy for the chromatin regulator BRD4.
Q46924536Bisphosphonate-Functionalized Hydroxyapatite Nanoparticles for the Delivery of the Bromodomain Inhibitor JQ1 in the Treatment of Osteosarcoma
Q33907067Chromatin-regulating proteins as targets for cancer therapy
Q34100931Histone deacetylase 2 and N-Myc reduce p53 protein phosphorylation at serine 46 by repressing gene transcription of tumor protein 53-induced nuclear protein 1
Q61796439Induction of GNMT by 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranoside through proteasome-independent MYC downregulation in hepatocellular carcinoma
Q92276520Inhibition of super enhancer downregulates the expression of KLF5 in basal-like breast cancers
Q92443585Nanoparticles Loaded with the BET Inhibitor JQ1 Block the Growth of Triple Negative Breast Cancer Cells In Vitro and In Vivo

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