Polycystic liver disease: new insights into disease pathogenesis

scientific article published on 01 May 2006

Polycystic liver disease: new insights into disease pathogenesis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/HEP.21199
P698PubMed publication ID16628666

P2093author name stringTatyana Masyuk
Nicholas LaRusso
P2860cites workThe gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like proteinQ24292750
Mutations in PRKCSH cause isolated autosomal dominant polycystic liver diseaseQ24531988
Identification of a locus for autosomal dominant polycystic liver disease, on chromosome 19p13.2-13.1Q24538950
Polycystic disease of the liverQ28283470
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cellsQ28505110
Effects of angiogenic factor overexpression by human and rodent cholangiocytes in polycystic liver diseasesQ28576110
Activation of the MEK5/ERK5 cascade is responsible for biliary dysgenesis in a rat model of Caroli's diseaseQ28578050
The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal ciliaQ29615732
The genetics and physiology of polycystic kidney diseaseQ34179146
An incredible decade for the primary cilium: a look at a once-forgotten organelleQ34465976
Polycystic kidney disease: new understanding in the pathogenesisQ34548724
Biliary dysgenesis in the PCK rat, an orthologous model of autosomal recessive polycystic kidney diseaseQ35103361
Molecular genetics of autosomal recessive polycystic kidney diseaseQ35637400
PKHD1, the polycystic kidney and hepatic disease 1 gene, encodes a novel large protein containing multiple immunoglobulin-like plexin-transcription-factor domains and parallel beta-helix 1 repeatsQ35764727
Liver disease in autosomal recessive polycystic kidney diseaseQ36263614
Matrix metalloproteinase activity in human intrahepatic biliary epithelial cell lines from patients with autosomal dominant polycystic kidney diseaseQ41248259
Epidermal growth factor receptor tyrosine kinase inhibition is not protective in PCK ratsQ45116487
Molecular characterization of hepatocystin, the protein that is defective in autosomal dominant polycystic liver disease.Q47368927
Defects in cholangiocyte fibrocystin expression and ciliary structure in the PCK rat.Q52552433
IL-6 induces hepatic inflammation and collagen synthesis in vivo.Q54638501
Interleukin-6 promotes cervical tumor growth by VEGF-dependent angiogenesis via a STAT3 pathwayQ61623437
Autosomal recessive polycystic kidney disease: long-term sonographic findings in patients surviving the neonatal periodQ72156999
Polycystic kidney disease--the ciliary connectionQ73087592
Treatment of polycystic kidney disease with a novel tyrosine kinase inhibitorQ73322106
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectpolycystic liver diseaseQ246002
P304page(s)906-908
P577publication date2006-05-01
P1433published inHepatologyQ15724398
P1476titlePolycystic liver disease: new insights into disease pathogenesis
P478volume43

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cites work (P2860)
Q33987179Activation of Trpv4 reduces the hyperproliferative phenotype of cystic cholangiocytes from an animal model of ARPKD.
Q37719446Case study: polycystic livers in a transgenic mouse line
Q37317821Cholangiociliopathies: genetics, molecular mechanisms and potential therapies
Q36277264Cholangiocyte cilia express TRPV4 and detect changes in luminal tonicity inducing bicarbonate secretion.
Q36953076Cholangiocyte primary cilia in liver health and disease
Q28572123HDAC6 is overexpressed in cystic cholangiocytes and its inhibition reduces cystogenesis
Q33703710Hepato-renal pathology in pkd2ws25/- mice, an animal model of autosomal dominant polycystic kidney disease
Q47125278Increased YAP Activation Is Associated With Hepatic Cyst Epithelial Cell Proliferation in ARPKD/CHF.
Q35185224Inhibition of metalloprotease hyperactivity in cystic cholangiocytes halts the development of polycystic liver diseases
Q30403670Liver masses: a clinical, radiologic, and pathologic perspective.
Q36075880Meningeal tumor: A rare extrahepatic association in patients with polycystic liver disease enrolled for liver transplantation
Q36945198MicroRNA15a modulates expression of the cell-cycle regulator Cdc25A and affects hepatic cystogenesis in a rat model of polycystic kidney disease
Q37431350MicroRNAs in cholangiociliopathies
Q28742454PPAR-gamma agonist ameliorates kidney and liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease
Q42174609Pathobiology of biliary epithelia and cholangiocarcinoma: proceedings of the Henry M. and Lillian Stratton Basic Research Single-Topic Conference
Q33949172Polycystic liver diseases.
Q35678557Proliferation-Independent Initiation of Biliary Cysts in Polycystic Liver Diseases
Q36667245Sirolimus reduces polycystic liver volume in ADPKD patients
Q40867711TGR5 in the Cholangiociliopathies

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