Spreading of prions from the immune to the peripheral nervous system: a potential implication of dendritic cells

scientific article published on 18 March 2010

Spreading of prions from the immune to the peripheral nervous system: a potential implication of dendritic cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00418-010-0687-9
P698PubMed publication ID20238136

P2093author name stringNadine Antoine
Ernst Heinen
Gauthier Dorban
Valérie Defaweux
P2860cites workOral scrapie infection modifies the homeostasis of Peyer’s patches’ dendritic cellsQ57357188
In Vivo Depletion of CD11c+ Cells Impairs Scrapie Agent Neuroinvasion from the IntestineQ64447652
The role of the spleen in the neuroinvasion of scrapie in miceQ69203477
Precise targeting of the pathology of the sialoglycoprotein, PrP, and vacuolar degeneration in mouse scrapieQ69356290
Early accumulation of PrP(Sc) in gut-associated lymphoid and nervous tissues of susceptible sheep from a Romanov flock with natural scrapieQ73209449
Pathogenesis of natural scrapie in sheepQ73530915
Microglia and the pathogenesis of spongiform encephalopathiesQ73605054
A two-step culture method starting with early growth factors permits enhanced production of functional dendritic cells from murine splenocytesQ73815751
Immmunohistochemical study of the blood and lymphatic vasculature and the innervation of mouse gut and gut-associated lymphoid tissueQ79697815
Prion protein activates and fixes complement directly via the classical pathway: implications for the mechanism of scrapie agent propagation in lymphoid tissueQ79871619
Interaction between dendritic cells and nerve fibres in lymphoid organs after oral scrapie exposureQ81154052
Interfaces between dendritic cells, other immune cells, and nerve fibres in mouse Peyer's patches: potential sites for neuroinvasion in prion diseasesQ81624391
Cell biology: The ins and outs of exosomesQ81885283
Mice devoid of PrP are resistant to scrapieQ28249108
Human neuroglobin interacts with flotillin-1, a lipid raft microdomain-associated proteinQ28259514
Intracerebral administration of interleukin-12 (IL-12) and IL-18 modifies the course of mouse scrapieQ33267751
Lipid rafts and clathrin cooperate in the internalization of PrP in epithelial FRT cellsQ33463351
Nanotubular highways for intercellular organelle transportQ34298770
Prions hijack tunnelling nanotubes for intercellular spreadQ34938949
Dendritic cells and oral transmission of prion diseasesQ35737892
Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapieQ36167962
Cells release prions in association with exosomesQ36448448
Prions and their partners in crimeQ36628157
The spread of prions through the body in naturally acquired transmissible spongiform encephalopathiesQ36731460
Temporary depletion of CD11c+ dendritic cells delays lymphoinvasion after intraperitonal scrapie infectionQ36845807
Processing and degradation of exogenous prion protein by CD11c(+) myeloid dendritic cells in vitroQ39686166
Subcellular localization of prion proteins and the 37 kDa/67 kDa laminin receptor fused to fluorescent proteinsQ40002708
The 37-kDa/67-kDa laminin receptor acts as a receptor for infectious prions and is inhibited by polysulfated glycanesQ40245615
Study on the toxic mechanism of prion protein peptide 106-126 in neuronal and non neuronal cellsQ40265130
The scrapie prion protein is present in flotillin-1-positive vesicles in central- but not peripheral-derived neuronal cell linesQ40427322
Scrapie protein degradation by cysteine proteases in CD11c+ dendritic cells and GT1-1 neuronal cellsQ40567838
Increased levels of insulin and insulin-like growth factor-1 hybrid receptors and decreased glycosylation of the insulin receptor alpha- and beta-subunits in scrapie-infected neuroblastoma N2a cellsQ40577873
Retrovirus infection strongly enhances scrapie infectivity release in cell cultureQ41445328
PrPc glycoform heterogeneity as a function of brain region: implications for selective targeting of neurons by prion strainsQ41692340
Processing of the bovine spongiform encephalopathy-specific prion protein by dendritic cellsQ42066262
Early and late pathogenesis of natural scrapie infection in sheepQ43684067
PrP(CWD) in the myenteric plexus, vagosympathetic trunk and endocrine glands of deer with chronic wasting diseaseQ43741429
Distribution of PrP(Sc) in cattle with bovine spongiform encephalopathy slaughtered at abattoirs in JapanQ44065375
Mucosal dendritic cells in immunity and inflammationQ45053078
Anatomical evidence for ileal Peyer's patches innervation by enteric nervous system: a potential route for prion neuroinvasion?Q46720348
Pathologic conformations of prion proteinsQ46894080
Early and rapid engraftment of bone marrow-derived microglia in scrapie.Q48375542
Molecular analysis of bovine spongiform encephalopathy and scrapie strain variationQ48400615
Transportation of prion protein across the intestinal mucosa of scrapie-susceptible and scrapie-resistant sheepQ48598161
PrP-expressing tissue required for transfer of scrapie infectivity from spleen to brainQ48630602
Scrapie pathogenesis: the role of complement C1q in scrapie agent uptake by conventional dendritic cellsQ48802665
Propagation of scrapie in peripheral nerves after footpad infection in normal and neurotoxin exposed hamsters.Q51801226
Migrating intestinal dendritic cells transport PrP(Sc) from the gut.Q53676141
Prion protein expression by mouse dendritic cells is restricted to the nonplasmacytoid subsets and correlates with the maturation state.Q54333660
Enteroglial and neuronal involvement without apparent neuron loss in ileal enteric nervous system plexuses from scrapie-affected sheepQ57083641
Transepithelial prion transport by M cellsQ57083694
Ileal tract and Peyer's patch innervation in scrapie-free versus scrapie-affected ovinesQ57131096
P433issue5
P304page(s)493-504
P577publication date2010-03-18
P1433published inHistochemistry and Cell BiologyQ1524012
P1476titleSpreading of prions from the immune to the peripheral nervous system: a potential implication of dendritic cells
P478volume133

Reverse relations

cites work (P2860)
Q35585058Expression of genes involved in the T cell signalling pathway in circulating immune cells of cattle 24 months following oral challenge with Bovine Amyloidotic Spongiform Encephalopathy (BASE).
Q37833524Histochemistry and cell biology: the annual review 2010.
Q38068103Immunotherapy in prion disease
Q37875484Misfolded protein aggregates: mechanisms, structures and potential for disease transmission
Q37911181Transmission of prions within the gut and towards the central nervous system

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