Distinct mechanisms of microRNA sorting into cancer cell-derived extracellular vesicle subtypes

scientific article published on 22 August 2019

Distinct mechanisms of microRNA sorting into cancer cell-derived extracellular vesicle subtypes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.7554/ELIFE.47544
P932PMC publication ID6728143
P698PubMed publication ID31436530

P50authorRandy SchekmanQ740638
Matthew J ShurtleffQ56910159
Alan M. LambowitzQ91233859
Ryan M NottinghamQ92072695
Morayma M Temoche-DiazQ92768504
Jun YaoQ92768510
Raj P FadaduQ92768514
P2093author name stringRandy Schekman
Jun Yao
Alan M Lambowitz
Ryan M Nottingham
Matthew J Shurtleff
Morayma M Temoche-Diaz
Raj P Fadadu
P2860cites workUnidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cellsQ24300024
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Rab27a and Rab27b control different steps of the exosome secretion pathwayQ24336455
La enhances IRES-mediated translation of laminin B1 during malignant epithelial to mesenchymal transitionQ24618219
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Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypesQ27317206
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Fast gapped-read alignment with Bowtie 2Q27860699
The Sequence Alignment/Map format and SAMtoolsQ27860966
MicroRNAs: genomics, biogenesis, mechanism, and functionQ27861070
Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifsQ28119049
The La proteinQ28202309
Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activityQ28255255
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KRAS-dependent sorting of miRNA to exosomesQ28646719
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Extracellular vesicles: exosomes, microvesicles, and friendsQ29618137
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HISAT: a fast spliced aligner with low memory requirementsQ34043398
Implication of RNA-binding protein La in proliferation, migration and invasion of lymph node-metastasized hypopharyngeal SCC cellsQ34053287
Differential phosphorylation and subcellular localization of La RNPs associated with precursor tRNAs and translation-related mRNAs.Q34278899
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MiR-122 inhibits cell proliferation and tumorigenesis of breast cancer by targeting IGF1R.Q34442762
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Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic propertiesQ34993023
Proteomic challenges: sample preparation techniques for microgram-quantity protein analysis from biological samplesQ35139099
Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via membrane-associated transforming growth factor-beta1.Q35193728
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Brain metastatic cancer cells release microRNA-181c-containing extracellular vesicles capable of destructing blood-brain barrierQ35407588
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Assessment of small RNA sorting into different extracellular fractions revealed by high-throughput sequencing of breast cell lines.Q35770652
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Sumoylation in axons triggers retrograde transport of the RNA-binding protein La.Q35921738
De novo sequencing of circulating miRNAs identifies novel markers predicting clinical outcome of locally advanced breast cancerQ35927834
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Cells release subpopulations of exosomes with distinct molecular and biological propertiesQ36638253
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Diverse subpopulations of vesicles secreted by different intracellular mechanisms are present in exosome preparations obtained by differential ultracentrifugationQ37141136
Reversible HuR-microRNA binding controls extracellular export of miR-122 and augments stress response.Q37141392
Y-box protein 1 is required to sort microRNAs into exosomes in cells and in a cell-free reactionQ37306053
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Differential RISC association of endogenous human microRNAs predicts their inhibitory potentialQ37701257
La protein is associated with terminal oligopyrimidine mRNAs in actively translating polysomesQ38352983
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Cellular disposal of miR23b by RAB27-dependent exosome release is linked to acquisition of metastatic propertiesQ38952925
Exosomal tumor microRNA modulates premetastatic organ cellsQ39182484
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.Q39242962
Fetal Bovine Serum RNA Interferes with the Cell Culture derived Extracellular RNAQ39509676
La protein has a positive effect on the translation of TOP mRNAs in vivoQ39542983
Packaging of prions into exosomes is associated with a novel pathway of PrP processing.Q40163902
The RNA-Binding Protein SYNCRIP Is a Component of the Hepatocyte Exosomal Machinery Controlling MicroRNA Sorting.Q40509270
BCR/ABL activates mdm2 mRNA translation via the La antigenQ40666171
Electron microscopic evidence for externalization of the transferrin receptor in vesicular form in sheep reticulocytesQ41479630
The impact of disparate isolation methods for extracellular vesicles on downstream RNA profilingQ41903415
Selective extracellular vesicle exclusion of miR-142-3p by oral cancer cells promotes both internal and extracellular malignant phenotypesQ41911174
Nontemplated nucleotide additions distinguish the small RNA composition in cells from exosomesQ42186566
PDGF enhances IRES-mediated translation of Laminin B1 by cytoplasmic accumulation of La during epithelial to mesenchymal transition.Q42213394
Broad role for YBX1 in defining the small noncoding RNA composition of exosomesQ42778300
COPII-coated membranes function as transport carriers of intracellular procollagen I.Q44943575
Endogenous RNAs modulate microRNA sorting to exosomes and transfer to acceptor cellsQ46058681
Neurodegeneration-associated mutant TREM2 proteins abortively cycle between the ER and ER-Golgi intermediate compartmentQ46166596
Different exosome cargo from plasma/bronchoalveolar lavage in non-small-cell lung cancer.Q46607964
Hypoxic lung cancer-secreted exosomal miR-23a increased angiogenesis and vascular permeability by targeting prolyl hydroxylase and tight junction protein ZO-1.Q47911670
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Cutadapt removes adapter sequences from high-throughput sequencing readsQ55953584
The La Autoantigen Is a Malignancy-Associated Cell Death Target That Is Induced by DNA-Damaging DrugsQ63681774
Purified lupus antigen La recognizes an oligouridylate stretch common to the 3' termini of RNA polymerase III transcriptsQ71000480
The RNA-binding protein La contributes to cell proliferation and CCND1 expressionQ85057853
Electrophoretic mobility shift assays for RNA-protein complexesQ87587531
Reassessment of Exosome CompositionQ92878002
P407language of work or nameEnglishQ1860
P921main subjectextracellular vesicleQ21097485
Multivesicular bodiesQ57979989
Extracellular vesiclesQ58039410
lupus laQ70298451
P577publication date2019-08-22
P1433published ineLifeQ2000008
P1476titleDistinct mechanisms of microRNA sorting into cancer cell-derived extracellular vesicle subtypes
P478volume8

Reverse relations

cites work (P2860)
Q91809247Cancer-Derived Extracellular Vesicle-Associated MicroRNAs in Intercellular Communication: One Cell's Trash Is Another Cell's Treasure
Q90736170Circulating Small Noncoding RNAs Have Specific Expression Patterns in Plasma and Extracellular Vesicles in Myelodysplastic Syndromes and Are Predictive of Patient Outcome
Q97525137Circulating miRNAs as Biomarkers in Aggressive B Cell Lymphomas
Q89762958Extracellular tRNAs and tRNA-derived fragments
Q98898225Identification of protein-protected mRNA fragments and structured excised intron RNAs in human plasma by TGIRT-seq peak calling
Q99565671Internalization of trophoblastic small extracellular vesicles and detection of their miRNA cargo in P-bodies
Q92644011Packaging RNA drugs into extracellular vesicles
Q95840447RNA delivery by extracellular vesicles in mammalian cells and its applications
Q99595135The evolving translational potential of small extracellular vesicles in cancer

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