Randomized clinical trial of antibiotic therapy versus appendicectomy as primary treatment of acute appendicitis in unselected patients

scientific article published on 01 May 2009

Randomized clinical trial of antibiotic therapy versus appendicectomy as primary treatment of acute appendicitis in unselected patients is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/BJS.6482
P698PubMed publication ID19358184

P50authorKent LundholmQ46900962
Amir Khorram-ManeshQ48371049
P2093author name stringJ Hansson
U Körner
A Solberg
P433issue5
P304page(s)473-481
P577publication date2009-05-01
P1433published inBritish Journal of SurgeryQ4970212
P1476titleRandomized clinical trial of antibiotic therapy versus appendicectomy as primary treatment of acute appendicitis in unselected patients
P478volume96

Reverse relations

cites work (P2860)
Q36452815A Systematic Review of Patient-reported Outcomes in Randomized Controlled Trials of Unplanned General Surgery
Q33763449A focus on intra-abdominal infections
Q40169177A lower neutrophil to lymphocyte ratio is closely associated with catarrhal appendicitis versus severe appendicitis
Q44630328A model to select patients who may benefit from antibiotic therapy as the first line treatment of acute appendicitis at high probability
Q48233275A prospective non-randomized controlled, multicenter trial comparing Appendectomy and Conservative Treatment for Patients with Uncomplicated Acute Appendicitis (the ACTUAA study).
Q34581199A prospective randomized controlled multicenter trial comparing antibiotic therapy with appendectomy in the treatment of uncomplicated acute appendicitis (APPAC trial).
Q38585100Acute Appendicitis in the Adult Population: Modelled Decision Analysis Supports a Conservative Approach
Q38721573Acute Appendicitis: Still a Surgical Disease? Results from a Propensity Score-Based Outcome Analysis of Conservative Versus Surgical Management from a Prospective Database
Q38007879Acute appendicitis in a developing country.
Q38355290Acute appendicitis in the elderly in the twenty-first century
Q37497021Acute appendicitis in the elderly: risk factors for perforation
Q86846451Acute appendicitis in the twenty-first century: should we modify the management protocol?
Q38605783Acute appendicitis: modern understanding of pathogenesis, diagnosis, and management
Q26774081Acute appendicitis: proposal of a new comprehensive grading system based on clinical, imaging and laparoscopic findings
Q51035217Amoxicillin plus clavulanic acid versus appendicectomy for treatment of acute uncomplicated appendicitis: an open-label, non-inferiority, randomised controlled trial.
Q37205412Analysis of Recurrence Management in Patients Who Underwent Nonsurgical Treatment for Acute Appendicitis
Q90026098Antibiotic therapy for acute uncomplicated appendicitis: a systematic review and meta-analysis
Q82363923Antibiotic therapy versus appendectomy for acute appendicitis: a meta-analysis
Q34527428Antibiotics Versus Appendicectomy for the Treatment of Uncomplicated Acute Appendicitis: An Updated Meta-Analysis of Randomised Controlled Trials
Q94500513Antibiotics alone as an alternative to appendectomy for uncomplicated acute appendicitis in adults: Changes in treatment modalities related to the COVID-19 health crisis
Q26777373Antibiotics alone versus appendectomy to treat uncomplicated acute appendicitis in adults: what do meta-analyses say?
Q50946362Antibiotics as first-line therapy for acute appendicitis: evidence for a change in clinical practice.
Q33926139Antibiotics versus appendectomy in the management of acute appendicitis: a review of the current evidence
Q40410020Antibiotics-First Versus Surgery for Appendicitis: A US Pilot Randomized Controlled Trial Allowing Outpatient Antibiotic Management
Q24235394Appendectomy versus antibiotic treatment for acute appendicitis
Q24240166Appendectomy versus antibiotic treatment for acute appendicitis
Q88323859Appendectomy versus non-operative treatment for acute uncomplicated appendicitis in children: study protocol for a multicentre, open-label, non-inferiority, randomised controlled trial
Q86206578Appendicitis
Q99629714Appendicitis is a Severe Disease in Elderly Patients: A Twenty-Year Audit
Q45814323Appendicitis-the balance between cost effectiveness and safety remains challenging.
Q46096643Appendicitis: is surgery the best option?
Q87369869Appendicolith delays resolution of appendicitis following nonoperative management
Q34258167Association Between Appendectomy and Clostridium difficile Infection
Q53081390Bacterial culture and antibiotic susceptibility in patients with acute appendicitis.
Q52676726CONTRACT Study - CONservative TReatment of Appendicitis in Children (feasibility): study protocol for a randomised controlled Trial.
Q88742434Can Surgery for Appendicitis Be Performed as an Outpatient Procedure?
Q26851801Case-based review: conservative management of appendicitis--are we delaying the inevitable?
Q41906216Change in the Diagnosis of Appendicitis by Using a Computed Tomography Scan and the Necessity for a New Scoring System to Determine the Severity of the Appendicitis
Q36262154Clinically monitored delay-A valid option in cases with doubtful diagnosis of acute appendicitis
Q36324086Comparison of Antibiotic Therapy and Appendectomy for Acute Uncomplicated Appendicitis in Children: A Meta-analysis
Q45073170Comparison of Outcomes of antibiotic Drugs and Appendectomy (CODA) trial: a protocol for the pragmatic randomised study of appendicitis treatment.
Q43185973Conservative or operative management (open or laparoscopic) of acute appendicitis
Q64983601Conservative treatment of acute appendicitis.
Q39422619Contemporary Management of Appendicitis in Children
Q89893036Continued increasing incidence of malignant appendiceal tumors in Canada and the United States: A population-based study
Q92172922Cost analysis of antibiotic therapy versus appendectomy for treatment of uncomplicated acute appendicitis: 5-year results of the APPAC randomized clinical trial
Q47893251Cost-effectiveness of prophylactic appendectomy: a Markov model
Q36104249Delayed Appendectomy Is Safe in Patients With Acute Nonperforated Appendicitis
Q40859420Delayed appendectomy because of diagnostic malpractice: Experiences of the Arbitration Board of the North German Medical Associations
Q37510838Delayed appendectomy versus early appendectomy in the treatment of acute appendicitis: a retrospective study
Q56536946Development of a core outcome set to determine the overall treatment success of acute uncomplicated appendicitis in children: a study protocol
Q36142204Diagnosis and management of acute appendicitis. EAES consensus development conference 2015
Q36619226Diagnostic value of procalcitonin for acute complicated appendicitis
Q48316844Do dietary spices impair the patient-reported outcomes for stapled hemorrhoidopexy? A randomized controlled study
Q92463399Early versus late surgical management for complicated appendicitis in adults: a multicenter propensity score matching study
Q35667182Effectiveness of Proadrenomedullin Enhanced CURB65 Score Algorithm in Patients with Community-Acquired Pneumonia in "Real Life", an Observational Quality Control Survey.
Q50062263Effects of Timing of Appendectomy on the Risks of Perforation and Postoperative Complications of Acute Appendicitis
Q92581570Effects of a Patient Activation Tool on Decision Making Between Surgery and Nonoperative Management for Pediatric Appendicitis: A Randomized Clinical Trial
Q38238253Endoscopic retrograde appendicitis therapy (ERAT) : a multicenter retrospective study in China
Q36010830Evaluation of the appendicitis inflammatory response score for patients with acute appendicitis
Q36626941Evidence for an Antibiotics-First Strategy for Uncomplicated Appendicitis in Adults: A Systematic Review and Gap Analysis
Q43511425Examining a common disease with unknown etiology: trends in epidemiology and surgical management of appendicitis in California, 1995-2009.
Q38736234Fast Track Surgery-Minimizing Side Effects of Surgery
Q33923181Feasibility of a nonoperative management strategy for uncomplicated acute appendicitis in children.
Q90084451Feasibility, acceptance, safety, and effectiveness of antibiotic therapy as alternative treatment approach to appendectomy in uncomplicated acute appendicitis
Q91836808Five-Year Follow-up of Antibiotic Therapy for Uncomplicated Acute Appendicitis in the APPAC Randomized Clinical Trial
Q37121448Fulminant Clostridium difficile infection: An association with prior appendectomy?
Q86865879Impact of routine contrast-enhanced CT on costs and use of hospital resources in patients with acute abdomen. Results of a randomised clinical trial
Q36095817Innovations in Endosurgery-Journey into the Past of the Future: To Ride the SILS Bandwagon or Not?
Q42016084Interval routine appendectomy following conservative treatment of acute appendicitis: Is it really needed
Q52779266Is acute appendicitis still misdiagnosed?
Q44295995Is amoxicillin plus clavulanic acid non-inferior to appendicectomy for the treatment of uncomplicated acute appendicitis?
Q60912299Is early appendectomy in adults diagnosed with acute appendicitis mandatory? A prospective study
Q47660385Laparoscopic appendectomy vs antibiotic therapy for acute appendicitis: a propensity score-matched analysis from a multicenter cohort study
Q35999393Laparoscopic management of intra-abdominal infections: Systematic review of the literature
Q58766596Letter to the Editor. Re: Conservative Management of Acute Appendicitis
Q41261309Long-Term Results Following Antibiotic Treatment of Acute Appendicitis in Adults.
Q34117169Long-term outcomes of patients with nonsurgically managed uncomplicated appendicitis
Q35771666Major abdominal surgery in nursing home residents: a national study
Q84107357Male gender is a risk factor for recurrent appendicitis following nonoperative treatment
Q92026366Medical Treatment: An Emerging Standard in Acute Appendicitis?
Q28072721Meta-analysis of antibiotics versus appendicectomy for non-perforated acute appendicitis
Q92621185Meta-analysis of studies comparing conservative treatment with antibiotics and appendectomy for acute appendicitis in the adult
Q35190168Meta-analysis of the therapeutic effects of antibiotic versus appendicectomy for the treatment of acute appendicitis
Q90271813Methods of conservative antibiotic treatment of acute uncomplicated appendicitis: A systematic review
Q41580585Monitoring C-reactive protein levels during medical management of acute appendicitis to predict the need for surgery
Q49990494Most medical practices are not parachutes: a citation analysis of practices felt by biomedical authors to be analogous to parachutes
Q90602807Never put equipoise in appendix! Final results of ASAA (antibiotics vs. surgery for uncomplicated acute appendicitis in adults) randomized controlled trial
Q93072399Nonoperative Management of Uncomplicated Appendicitis Among Privately Insured Patients
Q55006119Nonoperative management of appendiceal phlegmon or abscess in children less than 3 years of age.
Q92894218Operative Versus Nonoperative Management of Appendicitis: A Long-Term Cost Effectiveness Analysis
Q60044411Optimising the antibiotic treatment of uncomplicated acute appendicitis: a protocol for a multicentre randomised clinical trial (APPAC II trial)
Q35665342Outcome reporting in randomised controlled trials and meta-analyses of appendicitis treatments in children: a systematic review.
Q38981342Pediatric appendicitis: state of the art review.
Q36279675Predictive Factors to Distinguish Between Patients With Noncomplicated Appendicitis and Those With Complicated Appendicitis
Q53690200Prospective Observational Study on acute Appendicitis Worldwide (POSAW).
Q47686755Prospective validation of neutrophil-to-lymphocyte ratio as a diagnostic and management adjunct in acute appendicitis
Q89779280Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs Appendectomy for Uncomplicated Acute Appendicitis: A Secondary Analysis of a Randomized Clinical Trial
Q51752198Recurrence of acute appendicitis after non-operative treatment of appendiceal abscess in children: a single-centre experience.
Q24602653Safety and efficacy of antibiotics compared with appendicectomy for treatment of uncomplicated acute appendicitis: meta-analysis of randomised controlled trials
Q55515807Should ambulatory appendectomy become the standard treatment for acute appendicitis?
Q24236071Single incision versus conventional multi-incision appendectomy for suspected appendicitis
Q24235490Single incision versus conventional multi-incision appendicectomy for suspected appendicitis
Q37088896Single-Port Laparoscopic Interval Appendectomy for Perforated Appendicitis With a Periappendiceal Abscess
Q37555197Systematic review of clinical outcomes after prophylactic surgery
Q35319442The NOTA study: non-operative treatment for acute appendicitis: prospective study on the efficacy and safety of antibiotic treatment (amoxicillin and clavulanic acid) in patients with right sided lower abdominal pain
Q37563016The PIRO (predisposition, insult, response, organ dysfunction) model: toward a staging system for acute illness
Q36643706The Systemic Inflammatory Response in Patients with Appendicitis: a Progressive Phenomenon
Q42656074The current management of acute uncomplicated appendicitis: should there be a change in paradigm? A systematic review of the literatures and analysis of treatment performance
Q53110134The role of antibiotic therapy in the management of acute appendicitis.
Q42733596The role of high-mobility group box-1 (HMGB-1) in the management of suspected acute appendicitis: useful diagnostic biomarker or just another blind alley?
Q35889579The role of imaging in acute appendicitis and the need for histopathologic validation
Q35792943The value of hyperbilirubinaemia in the diagnosis of acute appendicitis
Q38370225Time to Appendectomy and Risk of Complicated Appendicitis and Adverse Outcomes in Children
Q93072377Treating the Patient With Appendicitis, Not Just the Appendicitis
Q35988244Uncomplicated acute appendicitis: is there a place for conservative treatment
Q38125614Uncovering malpractice in appendectomies: a review of 234 cases
Q39120360Use of Computed Tomography to Determine Perforation in Patients With Acute Appendicitis.
Q37286010Validity of predictive factors of acute complicated appendicitis
Q92953278WITHDRAWN: Endoscopic intervention for acute appendicitis: retrospective study of 101 cases
Q34541183WSES consensus conference: Guidelines for first-line management of intra-abdominal infections
Q58113253[Antibiotic treatment vs. appendectomy for non-perforated appendicitis in adults]
Q94475209[Antibiotics alone as an alternative to appendectomy for uncomplicated acute appendicitis in adults: changes in treatment modalities related to the COVID-19 health crisis]
Q94450697[Can Uncomplicated Adult Appendicitis Also Be Treated Conservatively?]

Search more.