Towards a better prediction of peak concentration, volume of distribution and half-life after oral drug administration in man, using allometry

scientific article published on 01 May 2011

Towards a better prediction of peak concentration, volume of distribution and half-life after oral drug administration in man, using allometry is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1037792543
P356DOI10.2165/11539250-000000000-00000
P698PubMed publication ID21456631

P2093author name stringJohan W Smit
Ron A H J Gilissen
Claire E Mackie
Luca A Fenu
Stefan S De Buck
Vikash K Sinha
Achiel Van Peer
Marjoleen Nijsen
Eva Hoeben
Wendy Sanderson
Karin Vaarties
Kelly Van Uytsel
P2860cites workPrediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding dataQ30697908
Prediction of hepatic metabolic clearance based on interspecies allometric scaling techniques and in vitro-in vivo correlationsQ33605312
Scaling basic toxicokinetic parameters from rat to man.Q34635619
Prediction of in vivo drug metabolism in the human liver from in vitro metabolism dataQ36857756
The prediction of human pharmacokinetic parameters from preclinical and in vitro metabolism data.Q36886681
Estimating xenobiotic half-lives in humans from rat data: influence of log P.Q36891261
Species similarities and differences in pharmacokinetics.Q41001138
Interspecies scaling: predicting clearance of drugs in humans. Three different approachesQ41189275
Prediction of hepatic clearance from microsomes, hepatocytes, and liver slicesQ41676765
Predicting oral clearance in humans: how close can we get with allometry?Q51898567
A compartmental absorption and transit model for estimating oral drug absorption.Q52204779
Interspecies scaling: predicting volumes, mean residence time and elimination half-life. Some suggestions.Q52240880
Some suggestions for measuring predictive performanceQ52875851
Prediction of human pharmacokinetics using physiologically based modeling: a retrospective analysis of 26 clinically tested drugs.Q53024733
Prediction of the disposition of beta-lactam antibiotics in humans from pharmacokinetic parameters in animalsQ70507453
Allometric pharmacokinetic scaling: towards the prediction of human oral pharmacokineticsQ73933451
Comparison of human duodenum and Caco-2 gene expression profiles for 12,000 gene sequences tags and correlation with permeability of 26 drugsQ78498262
Application of full physiological models for pharmaceutical drug candidate selection and extrapolation of pharmacokinetics to manQ81445372
P433issue5
P921main subjectallometryQ519888
P304page(s)307-318
P577publication date2011-05-01
P1433published inClinical PharmacokineticsQ5133788
P1476titleTowards a better prediction of peak concentration, volume of distribution and half-life after oral drug administration in man, using allometry
P478volume50

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cites work (P2860)
Q30844731First dose in neonates: are juvenile mice, adults and in vitro-in silico data predictive of neonatal pharmacokinetics of fluconazole
Q42680392Interspecies modeling and prediction of human exenatide pharmacokinetics
Q52690032Prediction of Human Pharmacokinetics of Ulixertinib, a Novel ERK1/2 Inhibitor from Mice, Rats, and Dogs Pharmacokinetics.
Q33955715Prediction of human oral plasma concentration-time profiles using preclinical data: comparative evaluation of prediction approaches in early pharmaceutical discovery
Q37216720Whole-exome sequencing identifies novel LEPR mutations in individuals with severe early onset obesity