HPV-18 E2^E4 chimera: 2 new spliced transcripts and proteins induced by keratinocyte differentiation

scientific article published on 27 April 2012

HPV-18 E2^E4 chimera: 2 new spliced transcripts and proteins induced by keratinocyte differentiation is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.VIROL.2012.03.023
P698PubMed publication ID22541938

P50authorFrançoise BachelerieQ57369063
P2093author name stringQian Wang
John Doorbar
Françoise Thierry
Jayantha Gunaratne
Laetitia Carthagena
Chye Ling Tan
Deborah Lai
Ling Shih Quek
Sophie Bellanger
Yue Zhen Xue
P2860cites workHigh-risk but not low-risk HPV E2 proteins bind to the APC activators Cdh1 and Cdc20 and cause genomic instabilityQ40362559
Nucleo-cytoplasmic shuttling of high risk human Papillomavirus E2 proteins induces apoptosis.Q40379237
Normal growth and differentiation in a spontaneously immortalized near-diploid human keratinocyte cell line, NIKS.Q40897907
Establishment of the human papillomavirus type 16 (HPV-16) life cycle in an immortalized human foreskin keratinocyte cell lineQ40926193
Specific interaction between HPV-16 E1-E4 and cytokeratins results in collapse of the epithelial cell intermediate filament networkQ41668848
Detection of novel splicing patterns in a HPV16-containing keratinocyte cell lineQ41723300
The majority of viral-cellular fusion transcripts in cervical carcinomas cotranscribe cellular sequences of known or predicted genesQ42650642
HPV16 E2 is an immediate early marker of viral infection, preceding E7 expression in precursor structures of cervical carcinomaQ44040831
Human papillomavirus type 16 expresses a variety of alternatively spliced mRNAs putatively encoding the E2 proteinQ45128755
The human papillomavirus type 18 (HPV18) replication protein E1 is a transcriptional activator when interacting with HPV18 E2Q74353238
Direct activation of caspase 8 by the proapoptotic E2 protein of HPV18 independent of adaptor proteinsQ81109530
Papillomavirus genome structure, expression, and post-transcriptional regulationQ22255483
The E1E4 protein of human papillomavirus type 16 associates with a putative RNA helicase through sequences in its C terminusQ24515067
Structure of the intact transactivation domain of the human papillomavirus E2 proteinQ27621566
A Functional interaction between the human papillomavirus 16 transcription/replication factor E2 and the DNA damage response protein TopBP1Q28212996
Interaction of the bovine papillomavirus E2 protein with Brd4 tethers the viral DNA to host mitotic chromosomesQ28258520
E1^E4-mediated keratin phosphorylation and ubiquitylation: a mechanism for keratin depletion in HPV16-infected epitheliumQ30495872
Differential control of Notch1 gene transcription by Klf4 and Sp3 transcription factors in normal versus cancer-derived keratinocytesQ33815952
Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristicsQ33962085
Construction of a full transcription map of human papillomavirus type 18 during productive viral infectionQ34193290
Identification of a G(2) arrest domain in the E1 wedge E4 protein of human papillomavirus type 16.Q34347454
E1 empty set E4 protein of human papillomavirus type 16 associates with mitochondriaQ34436669
Analysis of novel human papillomavirus type 16 late mRNAs in differentiated W12 cervical epithelial cellsQ36295157
Functional analysis of the human papillomavirus type 16 E1=E4 protein provides a mechanism for in vivo and in vitro keratin filament reorganization.Q36944507
A novel interaction between the human papillomavirus type 16 E2 and E1--E4 proteins leads to stabilization of E2.Q38350138
The human papillomavirus type 16 E7 oncogene is required for the productive stage of the viral life cycleQ39592146
Stability of the human papillomavirus type 18 E2 protein is regulated by a proteasome degradation pathway through its amino-terminal transactivation domainQ39606345
The human papillomavirus type 18 E2 protein is a cell cycle-dependent target of the SCFSkp2 ubiquitin ligase.Q39787520
P433issue1
P921main subjectkeratinocyteQ1473931
P304page(s)47-56
P577publication date2012-04-27
P1433published inVirologyQ7934867
P1476titleHPV-18 E2^E4 chimera: 2 new spliced transcripts and proteins induced by keratinocyte differentiation
P478volume429

Reverse relations

cites work (P2860)
Q28073341Control of human papillomavirus gene expression by alternative splicing
Q34593811Human papillomavirus type 1 E1^E4 protein is a potent inhibitor of the serine-arginine (SR) protein kinase SRPK1 and inhibits phosphorylation of host SR proteins and of the viral transcription and replication regulator E2
Q42271216The E4 protein; structure, function and patterns of expression
Q36152782The Replicative Consequences of Papillomavirus E2 Protein Binding to the Origin Replication Factor ORC2
Q37198619The papillomavirus E2 proteins
Q28542937The transcription map of human papillomavirus type 18 during genome replication in U2OS cells

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