The altered activity of complex III may contribute to the high penetrance of Leber's hereditary optic neuropathy in a Chinese family carrying the ND4 G11778A mutation

scientific article published on 01 July 2011

The altered activity of complex III may contribute to the high penetrance of Leber's hereditary optic neuropathy in a Chinese family carrying the ND4 G11778A mutation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.MITO.2011.06.006
P698PubMed publication ID21742061

P2093author name stringMin Liang
Min-Xin Guan
Jia Qu
Yaping Qian
Xiangtian Zhou
P2860cites workIdentification of an X-chromosomal locus and haplotype modulating the phenotype of a mitochondrial DNA disorderQ24538459
Clinical expression of Leber hereditary optic neuropathy is affected by the mitochondrial DNA-haplogroup backgroundQ24678122
Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementationQ29614475
Release of infectious Epstein-Barr virus by transformed marmoset leukocytesQ35093948
P433issue6
P921main subjecthereditary optic neuropathyQ55789244
P304page(s)871-877
P577publication date2011-07-01
P1433published inMitochondrionQ2122381
P1476titleThe altered activity of complex III may contribute to the high penetrance of Leber's hereditary optic neuropathy in a Chinese family carrying the ND4 G11778A mutation
P478volume11

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cites work (P2860)
Q35786077A method for mutagenesis of mouse mtDNA and a resource of mouse mtDNA mutations for modeling human pathological conditions
Q33916058A novel ADOA-associated OPA1 mutation alters the mitochondrial function, membrane potential, ROS production and apoptosis
Q40386722Biochemical Evidence for a Nuclear Modifier Allele (A10S) in TRMU (Methylaminomethyl-2-thiouridylate-methyltransferase) Related to Mitochondrial tRNA Modification in the Phenotypic Manifestation of Deafness-associated 12S rRNA Mutation
Q46515103Biochemical evidence for a mitochondrial genetic modifier in the phenotypic manifestation of Leber's hereditary optic neuropathy-associated mitochondrial DNA mutation.
Q37193896Coronary heart disease is associated with a mutation in mitochondrial tRNA.
Q36089268Leber's hereditary optic neuropathy is associated with the T3866C mutation in mitochondrial ND1 gene in three Han Chinese Families
Q53072695Mitochondrial haplotypes may modulate the phenotypic manifestation of the LHON-associated ND1 G3460A mutation in Chinese families.
Q45738904Mitochondrial tRNA mutations are associated with maternally inherited hypertension in two Han Chinese pedigrees
Q34172317Profiling the mitochondrial proteome of Leber's Hereditary Optic Neuropathy (LHON) in Thailand: down-regulation of bioenergetics and mitochondrial protein quality control pathways in fibroblasts with the 11778G>A mutation

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